Hierarchical classification of protein function with ensembles of rules and particle swarm optimisation

This paper focuses on hierarchical classification problems where the classes to be predicted are organized in the form of a tree. The standard top-down divide and conquer approach for hierarchical classification consists of building a hierarchy of classifiers where a classifier is built for each internal (non-leaf) node in the class tree. Each classifier discriminates only between its child classes. After the tree of classifiers is built, the system uses them to classify test examples one class level at a time, so that when the example is assigned a class at a given level, only the child classes need to be considered at the next level. This approach has the drawback that, if a test example is misclassified at a certain class level, it will be misclassified at deeper levels too. In this paper we propose hierarchical classification methods to mitigate this drawback. More precisely, we propose a method called hierarchical ensemble of hierarchical rule sets (HEHRS), where different ensembles are built at different levels in the class tree and each ensemble consists of different rule sets built from training examples at different levels of the class tree. We also use a particle swarm optimisation (PSO) algorithm to optimise the rule weights used by HEHRS to combine the predictions of different rules into a class to be assigned to a given test example. In addition, we propose a variant of a method to mitigate the aforementioned drawback of top-down classification. These three types of methods are compared against the standard top-down hierarchical classification method in six challenging bioinformatics datasets, involving the prediction of protein function. Overall HEHRS with the rule weights optimised by the PSO algorithm obtains the best predictive accuracy out of the four types of hierarchical classification method.     

A new adaptive backstepping Coulomb friction compensator for servo control systems

A new Coulomb friction compensator is proposed for servo control systems in this paper. The novelty of the new approach lies in its capability of assigning the eigenvalues of the resulting closed loop system while attacking the problem. First, based on the standard backstepping methodology, an implicit Lyapunov function, with part of the components being only symbolically constructed at the very beginning, is utilized. To increase the robustness of the system against disturbance and model inaccuracy, an integral term is employed in the design. Using part of the variable gradient method, we are able to turn the implicit Lyapunov function into an explicit one, which is positive definite, and whose time‐derivative is negative definite. Second, it will be shown that the resulting closed loop error system is a switched linear system with two possible active modes that share the same set of eigenvalues, which is at our disposal. Unlike the common adaptive control design methods, such as the Control Lyapunov Function approach, in which the gains are typically positive but otherwise arbitrary, and are hence difficult to choose and have a lack of connection with the system's performance, our new scheme imposes two further constraints on the gains. It turns out that we can then match these gains with the coefficients of the desired characteristic equation of the closed loop system. In this respect, the gains are linked to the system's overall performance, which is a new and very appealing feature for such a scheme. Finally, a procedure of constructing a common Lyapunov function is provided to prove exponential stability of the aforementioned switched linear system. In addition, using the invariance principle, we will show the convergence of the estimated Coulomb friction coefficient to its real value. Numerical simulations are given to validate the effectiveness of the design and its robustness against friction time‐variations. Compared to existing results, the proposed scheme is much simpler, hence, much more advantageous computationally. Copyright © 2009 John Wiley and Sons Asia Pte Ltd and Chinese Automatic Control Society     

建筑美学

把建筑定义为美学带有主观随意性,局限性,除了形式美,建筑还具有实用,经济,技术等价值。本文分别从建筑的形式美,使用功能,先进技术、环境特色等方面具体阐述建筑美学,对大多数人关心的建筑美学做一个冷静而深入的思考,探究这样一种美从何而来。     

固态功率组件热耦合效应研究

文中基于热叠加原理研究了固态功率组件中多个离散分布的集中热源的热耦合效应,并证明强迫对流下应用热叠加原理计算的温度场与整场系统数值模拟的结果相当吻合,用它来进行热耦合效应的分析研究是有效的.     

Surface Control and Electrical Tuning of MXene Electrode for Flexible Self-Powered Human–Machine Interaction

MXene materials emerge as promising candidates for energy harvesting and storage application. In this study, the effect of the surface chemistry on the work function of MXenes, which determines the performance of MXene-based triboelectric nanogenerator (TENG), is elucidated. First-principles calculations reveal that the surface functional group greatly influences MXene work function:  OH termination reduces the work function with respect to that of bare surface, while  F and  Cl increase it. Then, work functions are experimentally determined by Kelvin probe force microscopy. The MXene prepared by gentle etching at 40 °C for 48 h (GE_40/48) has the largest work function. Furthermore, an electron-cloud potential-well model is established to explain the mechanism of electron emission-dominated charge transfer and assemble a triboelectric device to verify experimentally its conclusions. It is found that GE_40/48 has the best performance with a 281 V open-circuit voltage, 9.7 µA short-current current, and storing 1.019 µC of charge, which is consistent with the model. Last, a patterned TENG is demonstrated for self-powered human–machine interaction application. This finding enhances the understanding of the inherent mechanism between the surface structure and the output performance of MXene-based TENG, which can be applied to other TENG based on 2D materials.     

Optimization of correlated multi-response quality engineering by the upside-down normal loss function

Most of the published literature on robust design is basically concerned with a single response. However, the reality is that common industrial problems usually involve several quality characteristics, which are often correlated. Traditional approaches to multidimensional quality do not offer much information on how much better or worse a process is when finding optimal settings. Köksoy and Fan [Engineering Optimization 44 (8): 935–945] pointed out that the upside-down normal loss function provides a more reasonable risk assessment to the losses of being off-target in product engineering research. However, they only consider the single-response case. This article generalizes their idea to more than one response under possible correlations and co-movement effects of responses on the process loss. The response surface methodology has been adapted, estimating the expected multivariate upside-down normal loss function of a multidimensional system to find the optimal control factor settings of a given problem. The procedure and its merits are illustrated through an example.     

Topological derivative-based technique for imaging thin inhomogeneities with few incident directions

Many non-iterative imaging algorithms require a large number of incident directions. Topological derivative-based imaging techniques can alleviate this problem, but lacks a theoretical background and a definite means of selecting the optimal incident directions. In this paper, we rigorously analyse the mathematical structure of a topological derivative imaging function, confirm why a small number of incident directions is sufficient, and explore the optimal configuration of these directions. To this end, we represent the topological derivative-based imaging function as an infinite series of Bessel functions of integer order of the first kind. Our analysis is supported by the results of numerical simulations.     

Inference for Weibull distribution under generalized order statistics

Based on generalized order statistics from Weibull distribution the approach of Bayesian and non-Bayesian estimation are discussed. We present a simple and efficient simulational algorithm for generating a generalized order statistics sample from any continuous distribution. Specializations to Bayesian and non-Bayesian estimators, some lifetime parameters and confidence intervals of progressive II censoring and record values are obtained and compared with the existing results. Two examples are given to illustrate the proposed estimators and the simulation algorithm.     

Integrating customer's preferences in the QFD planning process using a combined benchmarking and imprecise goal programming model

Quality function deployment (QFD) is a customer-oriented design tool for developing new or improved products to achieve higher customer satisfaction by integrating various functions of an organization. The engineering characteristics (ECs) affecting the product performances are designed to match the customer attributes (CAs). However, from the viewpoint of the QFD team, product design processes are performed in imprecise environments, and more than one factor must be taken into account in determining the target levels of ECs, especially the limited resources and increased market competition. This paper presents an imprecise goal programming (GP) approach to determine the optimum target levels of ECs in QFD for maximizing customer satisfaction under resource limitation and considerations of market competition. Based on benchmarking data of CAs, the concept of satisfaction functions is utilized to formulate explicitly the customer's preferences and to integrate the competitive analysis of target market into the modelling and solution process. In addition, the relationships linking CAs and ECs and the ECs to each other are integrated by functional relationships. The proposed approach will be illustrated through a car door design example.     

The structure of canalizing functions

The structure of a canalizing function is discussed. Using a new matrix product, namely semitensor product, the logical function is expressed in its matrix form. From its matrix expression, a criterion is obtained to test whether a logical function is a canalizing function. Then a formula is obtained to calculate the number of canalizing functions. Moreover, an algorithm is presented to generate canalizing functions. Finally, some results obtained are extended to seminested canalizing functions.