Anisotropy in Shape and Ligand‐Conjugation of Hybrid Nanoparticulates Manipulates the Mode of Bio–Nano Interaction and Its Outcome

In an attempt to manipulate the biological features of nanomaterials via both anisotropic shape and ligand modification, four types of nanoparticulates with good morphological stability are designed and engineered, including hybrid nanospheres, nanodiscs, and nanodiscs with edge modification or plane modification of octa‐arginine (R8) sequence. It is found that the R8 modification anisotropy can trigger huge differences in the endocytosis, intracellular trafficking, and even tissue penetration of nanoparticulates. From plane modification to edge modification of R8, the maximum increase in cell uptake is up to 17‐fold, which is much more significant than shape anisotropy alone. On the other hand, six types of different cell lines are investigated to simulate biological microenvironment. It is demonstrated that the maximum difference in cell uptake among six cell lines is 12‐fold. Three main driving forces are found to contribute to such bio–nano interactions. Based on the findings of this study, it seems possible to manipulate the biointeraction mode of nanomaterials and its output by regulating their anisotropy in both shape and ligand modification.     

模块化机器人双臂协调操作的实验研究

提出了利用optotrak3020三维测量系统获得精确位置信息来进行双臂机器人协调操作的方法。通过对双臂协调操作的运动约束进行分析,确定双臂协调运动的约束条件,同时将三维测量系统获得的空间三维坐标信息反馈到控制计算机,调整机器人末端的位置和姿态,以装配螺栓为例从运动学角度完成协调操作的实验。实验证明,利用optotrak3020三维测量系统获得精确位置信息对双臂机器人进行协调操作是有效的。     

基于细胞神经网络图像识别的刀具监控方法的研究

针对传统的刀具磨损状态监测方法与磨损程度无严格对应关系的缺点,提出一种新方法——采用普通的CCD摄像机拍摄刀尖形状的图像,经细胞神经网络图像处理后与正常的图像进行比较,判断刀具是否产生磨损。该系统可用于实现自动化精密加工过程中的实时在线工件形状监控和刀具诊断,仿真证明了理论算法的有效性。     

以磁场为控制场的量子比特系统量子态的最优制备

针对以磁场为控制场的电子自旋量子比特系统,结合量子门实现量子态幺正演化的量子态调控机制,提出了一种量子比特系统任意量子态的最优制备策略。建立了该量子比特系统及其控制场的模型,借助李群李代数,由经典最优控制的思想来获得最优控制,从而实现了电子自旋量子系统任意量子态的最优制备。理论分析与仿真实验显示了该策略的优越性。     

基于介质上电润湿的液滴产生器的研究

根据介质上电润湿的基本原理,对用于数字微流控系统的"三明治"结构器件中影响液滴输运和产生的因素进行了理论分析,并研制出了一种新型液滴产生器原型:液体被夹在上下两个电极板之间;下极板采用硅作为衬底、LPCVD掺杂多晶硅微电极阵列上热氧化生长的的SiO2薄膜作为介质层;上极板采用ITO透明导电玻璃板作为地电极;另外,在上下极板的表面都均匀旋转涂覆了一层30 nm厚的Teflon薄膜为表面疏水层.实验结果表明,在空气气氛中,该器件在10 Hz 70 V的脉冲电压下成功地实现了从蓄水池中对去离子水滴的分发.     

纤维横截面切片技术改进

针对纤维切片器在长期检测中普遍存在的制作纤维横截面切片成功率低、工作效率低、安全性较差等问题,对使用操作方法进行了改进和完善,并简单比较了切片照片的处理方法。     

Student perceptions of model-based estimating

The use of building information modeling (BIM) is well established in architecture, engineering and construction. However, previous studies note a lack of BIM expertise in academia, leading to slow adoption and limited knowledge on which to base BIM-related content. To improve course development, it is important to understand students’ perceptions of BIM-related subject matter. This study exposed estimating students (n = 214) to a model-based quantity takeoff (QTO) tutorial using Revit. Students’ perceptions of a Revit-based BIM’s usefulness for easily providing reliable and accurate material quantities were measured using a pre-test, tutorial and post-test design. Results revealed significant differences in students’ mean levels of agreement that an accurate QTO is completed for an estimator with the click of a button when a design team generated BIM model is available. Results also revealed significant differences in students’ level of agreement that a Revit-based BIM makes performing QTO by hand obsolete. This study provides educators’ insight into students’ perceptions of BIM use in QTO. Understanding student perceptions is paramount for construction management educators when designing a course and attempting to convey the value of foundational estimating skills while acknowledging the existence of more technologically advance estimating methods. Limitations and opportunities for further research are discussed.     

PowerBuilder中基于Blob类型数据的图像处理方法

以PowerBuilder8.0为工具,基于Blob类型的数据。得到一种图像处理方法,可以在应用软件开发中添加对声音、图像等特殊大文本对象的支持。     

旁路全程自动在中压缸启动汽轮机组中的实现

描述了中压缸启动机组的旁路全程控制的方法,指明了控制过程中的关键点,并结合某电厂600 MW机组中压缸启动的控制过程,介绍了实现旁路全程自动的具体操作方法。