基于Modbus现场总线的综采工作面大型设备监测监控系统

简要介绍了Modbus通讯协议,重点阐述了综采工作面大型设备实现远程监测监控功能的软硬件技术方案。在HT6L1-400Z/1140智能型组合电器的基础上采用Modbus现场总线,编制了通讯程序,实现了综采工作面大型设备的远程监测监控。     

采煤机位置监测装置的原理与应用

介绍了采煤机位置监测装置的主要功能、组成、工作原理以及应用。     

分布式监测诊断系统总体设计思想的研究

研究了分布式监测诊断系统的基本理论框架,提出了分布式监测诊断系统的定义、层次结构和各层的功能定义,并分析了分布式监测诊断系统与生产控制系统的关系。     

Development and Use of a Kinetical and Real-Time Monitoring System to Analyze the Replication of Hepatitis C Virus

In microbiological research, it is important to understand the time course of each step in a pathogen’s lifecycle and changes in the host cell environment induced by infection. This study is the first to develop a real-time monitoring system that kinetically detects luminescence reporter activity over time without sampling cells or culture supernatants for analyzing the virus replication. Subgenomic replicon experiments with hepatitis C virus (HCV) showed that transient translation and genome replication can be detected separately, with the first peak of translation observed at 3–4 h and replication beginning around 20 h after viral RNA introduction into cells. From the bioluminescence data set measured every 30 min (48 measurements per day), the initial rates of translation and replication were calculated, and their capacity levels were expressed as the sums of the measured signals in each process, which correspond to the areas on the kinetics graphs. The comparison of various HuH-7-derived cell lines showed that the bioluminescence profile differs among cell lines, suggesting that both translation and replication capacities potentially influence differences in HCV susceptibility. The effects of RNA mutations within the 5′ UTR of the replicon on viral translation and replication were further analyzed in the system developed, confirming that mutations to the miR-122 binding sites primarily reduce replication activity rather than translation. The newly developed real-time monitoring system should be applied to the studies of various viruses and contribute to the analysis of transitions and progression of each process of their life cycle.     

高速轧机润滑油品含水率实时检测系统的设计与应用

本文简要介绍了高速轧机润滑油品含水率实时检测系统的设计内容与应用情况,本系统使用效果明显,在国内本专业领域处于领先地位。     

电容器故障监测系统的应用研究

基于近年并联电容器装置频繁出现故障的现象和特点,研制出一套电容器故障监测系统,分别提取并联电容器装置的电流和电压实时信号,利用Labview虚拟仪器程序进行软件开发实现在线监测,对获取的电流电压信号进行谐波、合闸涌流、暂态过电压等方面进行分析和研究,并应用于现场测量,给出了一起电容器内部击穿故障的监测实例。     

IFIX在卷烟厂自动化生产物流监控系统中的应用

介绍了iFIX工控组态软件在卷烟厂的自动化生产物流监控系统中的应用。详细论述了生产物流监控系统的结构、组态过程、软硬件配置及软件设计等。可见iFIX在大型复杂生产物流分布式控制系统中的应用是可行的,保障了生产过程的连续运行,同时降低了生产制造成本。     

125 MN挤压机挤压中心在线监测系统设计

125 MN挤压机挤压中心检测目前采用人工测量计算法,工作量大且精度低.本文在分析常见光电位置检测方法的基础上,结合激光技术和图像处理技术,设计了一种新的挤压中心在线监测系统.阐述了该监测系统的原理和实施方案,建立了中心偏移量和偏转角度计算的几何模型,推导了计算公式,进行了模拟试验并做了误差分析.系统可同时对穿孔横梁、穿孔动梁、固定横梁、活动横梁和挤压容室进行在线监测,监测距离达35 m.     

架空输电线路环境荷载响应与设计理论的研究

我国地域广阔, 气候跨区域变化较大, 地形地貌复杂多变, 各地区风、雨以及导线覆冰的分布规律千差万别。由于目前环境荷载因素对输电塔线结构的严重破坏频繁发生, 造成了巨大的经济损失。因此, 有必要建立输电塔线结构环境荷载响应分析理论和进行设计优化, 提高其结构设计的规范水准, 并加强灾害监测控制。这对减轻环境荷载造成的输电塔线结构的灾害具有不可估量的作用。     

Improving the Management of Endometrial Cancer Patients through the Use of Liquid Biopsy Analyses: A Case Report

Endometrial cancer (EC) is the 4th most common neoplasm of the female genital tract, with 15–20% of patients being of high risk of recurrence which leads to a significant decrease in patient survival. Current therapeutic options for patients with EC are poor, being the combined therapy of carboplatin and paclitaxel the standard of care, with limited efficacy. Therefore, new therapeutic options and better monitoring tools are needed to improve the management of the disease. In the current case report, we showcase the value of liquid biopsy analyses in a microsatellite instability EC patient with initially good prognosis that however underwent rapid progression disease within 6 months post-surgery; through the study of plasma cfDNA/ctDNA dynamics to assess the tumour evolution during treatment, as well as the study of the uterine aspirate as a valuable sample that captures the intra-tumour heterogeneity that allows a comprehensive genomic profiling of the disease to identify potential therapeutic options. Furthermore, preclinical models were generated at the time of tumour progression to assess the efficacy of the identified targeted therapies.