基于自适应分块的动态场景HDR图像合成算法

通过提出基于梯度上升优化处理的自适应分块算法与基于图像序列梯度域运动检测与去除相结合的方法,自适应调整分块大小及动态区域块的融合权值,最终达到混淆去除的目的.同时,利用Gaussian中心函数窗口滤波,去除在分块融合过程中引入的块边缘不连续性痕迹.实验结果表明,该方法能快速有效地增强多曝光图像融合生成HDRI并去除混淆问题.     

一种新的基于压缩传感理论解决Pan-Sharpening问题的算法

Pan-Sharpening问题是将高分辨率全色图像和低分辨率多光谱图像融合,重构出高分辨率多光谱图像的过程。压缩传感理论解决了相应目标函数的稀疏解问题(求解含有l0范数的极小化问题)。利用压缩传感理论,提出一种新的解决Pan-Sharpening问题的算法:以离散余弦变换矩阵作为字典进行重构。然后针对重构过程中产生的块效应、色彩偏差和洗涤效应等问题进行相应的处理。QuickBird卫星图像的实验结果表明:与经典算法进行对比,该算法在效果上有一定的优势。     

Bioactive IL7-diphtheria fusion toxin secreted by mammalian cells

A number of targeted cytotoxic agents have been developed that selectively kill malignant or otherwise pathological cells. These engineered proteins consist of a potent cytotoxic element connected to a ligand domain that binds to specific molecules on the surface of the target cell. Several of these agents have shown promise in clinical trials and one is currently administered to patients. A significant technical obstacle that has impeded the development of some of these toxins is the difficulty of preparing certain recombinant proteins in properly folded forms. These fusion proteins have generally been produced in bacteria requiring them to be denatured and renatured in vitro. For some proteins this is an efficient process whereas for others it is not. We describe here a system to produce fusion toxins rapidly and efficiently by engineering mammalian cells to secrete them as properly folded molecules which can be purified in native form from cell culture medium. We have used this system to produce highly active preparations of DAB(389)-IL7, a molecule consisting of the catalytic and transmembrane domains of diphtheria toxin fused to interleukin 7. This system is generalizable and can be used to produce and evaluate rapidly fusion toxins incorporating novel or uncharacterized ligands.     

基于无线传感网的智能环境监控系统设计

针对传统环境监控系统存在的缺点,设计了一种新型无线传感器网络的环境监控系统。系统采用分布式融合结构,通过终端节点的多种传感器采集环境信息,终端对信息预处理后实时将信息传输到协调器。协调器融合各终端传感器信息,提取精确信息上传至融合中心,融合中心通过分析数据发布命令给控制中心,控制中心利用单片机驱动电机可以自动或手动控制风机和水泵对环境进行调节和控制。同时,系统还具有自动预警功能。通过验证,该系统稳定、可靠,能广泛应用于不同领域的分布式多点环境监控。     

基于Linux+ARM的多格式视频图像采集系统的设计

设计了基于S3C2440微处理器的视频图像采集系统,详细分析了该系统的启动过程。在一块裸板上搭建起整个视频图像采集系统。结合V4L2技术完成了支持YUV、MJPEG图像格式的USB摄像头和支持RGB图像格式的CMOS摄像头的多格式视频图像采集系统。测试结果表明,该系统可以在LCD显示屏上动态显示多格式摄像头所采集到的视频图像,且视频图像具有清晰度高、流畅性好、稳定性强等特点,具有进一步推广使用的广阔前景。     

Pattern recognition for characterization of pharmaceutical powders

A large part of pharmaceutical manufacturing involves the use of particulate materials. It is well known that both particle size and shape affect the physical characteristics of tablets. An image processing and analysis algorithm based on the invariant image moment technique was developed in this work to determine the particle shape by comparing features (moments) extracted from templates to those extracted from each of the objects in the image. First it determines the particle shape (rectangle, circle, etc.) and then calculates its specific dimensions (diameter, aspect ratio).The statistical validation of the vision system obtained a repeatability of 0.0012 in and 0.5% relative standard deviation and accuracy within 0.1 to 0.9% of the average value considered as true value. Also the pattern recognition technique indicated high precision and accuracy for images containing particles with some level of contact between them. The shape recognition of microcrystalline cellulose (MCC) indicated that particles of equant and acicular shape as defined by USP are predominant. The results suggest that image processing and analysis would be a suitable tool for pharmaceutical process analytical technologies (PAT) and process optimization.     

基于粒子群三次样条优化的图像边缘描述算法

针对手工选点生成的三次样条曲线无法准确地描述图像边缘的问题,以粒子群三次参数样条曲线优化算法为基础对现有的图像边缘算法进行了改进。在图像边缘上取若干点作为样条曲线的型值点,利用粒子群算法对这些型值点进行优化,使得到的样条曲线对图像边缘有很好的贴合。实验表明,该算法不仅能够快速拟合样条曲线,而且优化后的样条曲线形态能较好地贴合图像边缘轮廓。     

多尺度空间特征提取的脊柱图像拼接算法

针对脊柱图像视野有限,提出一种基于优化MSFE的脊柱图像自动拼接算法。设计出一种基于尺度因子变化的高斯卷积模板尺寸自适应调整以及双向配对办法;相似性度量采用城市距离;利用RANSAC算法去除错配,从而确定待拼接图像之间的变换参数,最后利用加权平均对图像融合。对实际取得的多幅脊柱图像拼接结果表明该算法具有很好的实时性和鲁棒性。     

便携心电传感器的心房肥大诊断研究

基于便携式传感器的模式识别在心电(ECG)监护领域具有广泛的应用前景,并且在心律不齐、心肌梗塞、心室肥大等心电的识别算法上都已有大量的研究与应用,但在心房肥大诊断上却未有模式识别相关的研究成果。心房肥大病症的心电数据量不足给研究造成重大障碍,部分分类器无法适应小样本训练下的分类。针对小样本训练进行研究,对比了不同分类方法,显示了基于统计模式识别的支持向量机(SVM)应用于心房肥大的应用潜力。另外,由于不同个体的心房肥大心电存在差异,在实际应用环境中,SVM存在无法良好泛化的问题,存在类别错分的医学风险。针对类别错分情况,采用分类器融合的方法改进分类器,提出了在SVM分类器输出端增加了拒绝域的分类器(SVM-R)的方法。实验结果表明:SVMR有较高的分类准确率与诊断可信度。     

合成煤中钠对煤燃烧及灰特性影响

准东煤中钠含量高，燃用时锅炉会出现严重结渣问题。通过向准东煤为原料制取的超纯煤中添加灰的模型化合物，得到合成煤。并在此基础上利用热重-差示扫描量热分析法（TG/DTG/DSC）、X射线衍射仪（XRD）和灰熔融温度测定分析手段，研究Na₂O含量对煤燃烧特性和灰熔融性的影响。结果表明：钠主要影响合成煤的着火温度（T_i）与焦炭燃烧阶段，钠含量增加使T_i升高，并且Na₂O在灰中质量分数由5%升高至8%后，钠含量增加使焦炭燃烧速率先减小后加快，并能够改善煤粉燃尽特性。钠能够降低灰熔融温度，并在Na₂O质量分数高于5%后，温度下降更加明显。在三元相图中钠对莫来石的助熔作用是造成灰熔融温度降低的重要原因。XRD分析表明Na₂O含量增加，充当骨架作用的石英在钠的助熔作用下与难熔矿物硅钙石、MgO等生成低熔点长石类矿物，这类矿物在高温下有助熔作用，能够降低灰熔融温度。同时还生成助熔性含钠矿物霞石，加剧了灰熔融。