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11.
针对电梯运行过程中存在爬行距离的问题,提出了基于RBF(Radial Basis Function)神经网络的爬行距离预测模型.将预测的爬行距离增加到电梯速度曲线的匀速段,实现减小或消除爬行距离的目的,从而实现电梯的零速停靠.从电梯运行现场采集大量的原始数据,建立RBF神经网络预测模型,与BP(Back Propagation)预测方法进行仿真比较,结果表明RBF神经网络具有更好的预测效果.给出了应用零速停靠RBF预测算法前后电梯运行的速度曲线,爬行距离减小或消除,电梯的运行时间变短,实现了节能. 相似文献
12.
The hydrophobic-polar (HP) lattice model is an important simplified model for studying protein folding. In this paper, we present an improved ACO algorithm for the protein structure prediction. In the algorithm, the "lone"ethod is applied to deal with the infeasible structures, and the "oint mutation and reconstruction"ethod is applied in local search phase. The empirical results show that the presented method is feasible and effective to solve the problem of protein structure prediction, and notable improvements in CPU time are obtained. 相似文献
13.
由于空泡及滑行力的存在,使得超空泡航行体的建模及控制问题变得非常复杂,在其模型简化过程中会产生一定的建模误差,采用鲁棒极点配置算法进行超空泡航行体控制可以有效克服这一缺点.对超空泡航行体所受的流体动力、尤其是滑行力的动态特性进行了分析整理;建立了超空泡航行体纵平面内的动力学模型;最后利用鲁棒极点配置算法设计了控制器.仿真结果表明,该控制系统具有较强的鲁棒性及稳定性.对各控制变量的控制效果进行了对比分析,分析结果表明空化器比尾舵具有更好的控制效果. 相似文献
14.
A study of structural determinants in the interleukin-1 fold 总被引:1,自引:0,他引:1
Swindells Mark B.; Thornton Janet M. 《Protein engineering, design & selection : PEDS》1993,6(7):711-715
The structures of interleukin-1ß, basic fibroblastgrowth factor and Erythrina trypsin inhibitor have been analysedin order to determine whether the hydrophobic core remains conserved,even when the structures have extremely low sequence similarities.We find that there are significant differences in the way eachprotein achieves a satisfactory arrangement of core residuesand that positions which contribute to the core of one structureare not guaranteed to contribute to the integrity of another.Furthermore, the side-chain packing arrangements of these coreresidues vary significantly between the three structures. Duringthis analysis the side-chain rotamers for three independentlydetermined interleukin-1ß structures were also compared.It was found that although buried residues are generally inagreement the remaining residues frequently occupy differentrotamers in the three structures. This suggests that althoughmeaningful studies are possible for buried side-chains the resultsobtained from equivalent analyses of accessible residues shouldbe treated with caution. These results are discussed with specificreference to the optimization of side-chain packing in proteinsof known structure. 相似文献
15.
Zvelebil Marketa J.J.M.; Wolf C.Roland; Sternberg Michael J.E. 《Protein engineering, design & selection : PEDS》1991,4(3):271-282
A three-dimensional structure for human cytochrome P450IA1 waspredicted based on the crystal coordinates of cytochrome P450camfrom Pseudomonas putida. As there was only 15% residue identitybetween the two enzymes, additional information was used toestablish an accurate sequence alignment that is a prerequisitefor model building. Twelve representative eukaryotic sequenceswere aligned and a net prediction of secondary structure wasmatched against the known -helices and ß-sheets ofP450cam. The cam secondary structure provided a fixed main-chainframework onto which loops of appropriate length from the humanP450IA1 structure were added. The model-built structure of thehuman cytochrome conformed to the requirements for the segregationof polar and nonpolar residues between the core and the surface.The first 44 residues of human cytochrome P450 could not bebuilt into the model and sequence analysis suggested that residues126 formed a single membrane-spanning segment. Examinationof the sequences of cytochrome P450s from distinct gene familiessuggested specific residues that could account for the differencesin substrate specificity. A major substrate for P450IA1, 3-methyl-cholanthrene,was fitted into the proposed active site and this planar aromaticmolecule could be accommodated into the available cavity. Residuesthat are likely to interact with the haem were identified. Thesequence similarity between 59 eukaryotic enzymes was representedas a dendrogram that in general clustered according to genefamily. Until a crystallographic structure is available, thismodel-building study identifies potential residues in cytochromeP450s important in the function of these enzymes and these residuesare candidates for site-directed mutagenesis. 相似文献
16.
Zhou Weixian Department of Aeronautical Manufacturing Engineering Northwestern Polytechnical University Xi′an 《中国有色金属学会会刊》1997,(1)
DEPENDENCEOFPREDICTIONMODELOFFORMINGLIMITSTRAINSONFORMINGMETHODANDMECHANICALPROPERTIESOFSHEETMETALS①ZhouWeixianDepartmentofAe... 相似文献
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AVS-M是我国拥有自主知识产权的数字音视频编码系列标准的移动视频标准.AVS-M采用率失真优化(RDO)技术进行帧间模式的选择,增加编码过程中宏块进行模式选择的计算复杂度.本文提出一种快速的帧间模式选择算法.该算法首先对SKIP模式提前判决,再采用二分搜索法对帧间模式的选择,对于宏块层的模式划分采用MAD(平均绝对差... 相似文献