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111.
CPL: Detecting Protein Complexes by Propagating Labels on Protein-Protein Interaction Network
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Proteins usually bind together to form complexes, which play an important role in cellular activities. Many graph clustering methods have been proposed to identify protein complexes by finding dense regions in protein-protein interaction networks. We present a novel framework (CPL) that detects protein complexes by propagating labels through interactions in a network, in which labels denote complex identifiers. With proper propagation in CPL, proteins in the same complex will be assigned with the same labels. CPL does not make any strong assumptions about the topological structures of the complexes, as in previous methods. Tile CPL algorithm is tested on several publicly available yeast protein-protein interaction networks and compared with several state-of-the-art methods. The results suggest that CPL performs better than the existing methods. An analysis of the functional homogeneity based on a gene ontology analysis shows that the detected complexes of CPL are highly biologically relevant. 相似文献
112.
113.
赣江下游尾闾综合整治工程物理模型建于室外,且模拟河流多级分叉,对整个模型测控系统运行的可靠性以及室外的防雷性能提出了更高的要求。在分析现场情况的基础上,提出了一套较为先进的模型量测控制系统总体设计方案,控制系统由平水塔供水系统、流量控制系统、水位与流速测量系统、尾门控制系统、防雷接地系统、地形测量系统等量测子系统组成。简要介绍了各测量子系统工作原理,设计方案及实际应用情况,系统应用现代网络技术及高性能自动化测量仪器,可实现模型试验中各种参数的实时采集、控制和数据处理。试验结果表明,该测控系统可满足模型试验的测控需求。 相似文献
114.
岩石在荷载作用下产生宏观破坏,其破裂面细观形态变化可以直接地反映出结构破坏特征。目前,常采用扫描电镜法、透镜法和CT扫描技术对岩石细观结构进行表征。运用CT扫描技术对典型脆性岩样单轴压缩破坏后破裂面及全断面进行扫描,获取全断面的细观形态,分析和总结了典型脆性岩样破坏细观裂纹扩展的发展规律:每一条独立裂纹都以一恒定曲率半径系数K随层位向试样内部扩展,直至裂纹曲率半径趋近于无穷。此时若无其他因素影响,其曲率半径则不会再随层位继续扩展;并通过分析定义出岩石脆性破坏状态时裂纹的聚集域和非聚集域,同时根据能量守恒定律得出了衍生裂纹及新次生裂纹产生的判据。 相似文献
115.
The alignment of information systems with the business goals of an organisation, although a topic of great importance, is not always properly valued or taken into consideration. In general, managers have different opinions to chief information officers (CIOs) in relation to IS, especially with regard to their importance and value to the business and also in terms of investment needs. Here, we discuss and study new approaches to methods and tools for assessing the relative importance of each information system to business, focusing on the financial sector including banks and insurance companies. We suggest the introduction of new key indicators for better decision support and to identify investment priorities, and present results regarding the relative importance of each process to support the business strategy. The primary goal for the inherent research project is to analyse the main problems and difficulties encountered by IS and IT managers, featuring different players and how they relate. The main contributions of this work are the CRUDi framework as a tool to improve alignment between business and IS strategies and the CRUDi survey and its results qualifying the financial sector's opinion regarding the relative importance of processes and investments. 相似文献
116.
B. P. Aduev É. D. Aluker A. G. Krechetov A. Yu. Mitrofanov 《Combustion, Explosion, and Shock Waves》2003,39(6):701-703
The velocity of the chain explosivedecomposition reaction in silver azide whiskes has been measured (1500 m/sec). The measured velocity is identified as the propagation velocity of the diffusion front of holes generated in the course of explosive decomposition. 相似文献
117.
118.
A numerical modeling study of the propagation of a laminar flat homogeneous gas flame has shown that in a hydrogen-air flame,
a rapid increase in the concentration of OH radicals begins in the range of low temperatures and the concentration profile
has two maxima. The first maximum in the low-temperature region of the front is related to the diffusion of H atoms, formation
of HO2 radicals, and the quadratic branching reaction H + HO2 → OH + OH. The second maximum in the OH concentration profile is due to the classical high-temperature branching reactions
H + O2 → OH + O and O + H2 → OH + H.
__________
Translated from Fizika Goreniya i Vzryva, Vol. 43, No. 2, pp. 3–9, March–April, 2007. 相似文献
119.
In this study, we analyze data from surveys conducted in 2006 and 2010, tracking changes in awareness, engagement and attitudes surrounding emerging digital cultural forms over this 5‐year period. Our analysis, based on results from thousands of adults around the globe, shows that not only have remixes, mashups and other forms of “configurable culture” become mainstream phenomena, but also that the attitudes surrounding their cultural legitimacy are shifting. While copyright industries still promote a binary theft/permission framework, many people acknowledge the validity of some appropriation, and are actively negotiating the law's limitations. Yet, those most engaged in challenging dominant copyright narratives and exploring these emergent forms are those who hold the reins of cultural power: the young, educated and wealthy. 相似文献
120.