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目的:探讨富硒沼泽红假单胞菌G3 菌(简称富硒G3 菌)与牛初乳复配对小鼠免疫功能的影响。方法:将富G3 菌与牛初乳复配形成富硒牛初乳,用环磷酰胺构建小鼠免疫低下模型,对免疫低下小鼠灌胃富硒G3 菌、牛初乳和富硒牛初乳,50d 后测定各组小鼠脏器指数、白细胞数、T 淋巴细胞阳性率、血清SOD 酶活性、全血GSH-Px活性,同时计算平均每日进食饲料质量与体质量增加量的比值。结果:富硒G3 菌、牛初乳、富硒牛初乳均能提高免疫低下小鼠对饲料的利用率,能提高免疫低下小鼠SOD、GSH-Px 活性、白细胞数和T 淋巴细胞阳性率,其中富硒牛初乳高剂量组效果最为明显,说明富硒牛初乳高剂量组能显著增强小鼠的免疫功能。 相似文献
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The voting system studied consists of n voting units each either providing a binary decision (0 or 1) or abstaining from voting. The system output is 1 if the cumulative weight of all 1-opting units is at least a pre-specified fraction τ of the cumulative weight of all non-abstaining units. Otherwise, the system output is 0.In this paper, we study the effect of limited availability of the voting units on the entire voting system reliability. Two different types of systems are considered. In the system of type 1, the absence of unit output (unit unavailability) is interpreted by the system as abstention from voting. In the system of type 2, the unavailable state of the voting unit and its abstention from voting can be distinguished and the system parameters can be adjusted to optimize its performance for each combination of available units.There are two ways to improve reliability of weighted voting system consisting of units with the given output probability distribution: optimization of system parameters (weights of units and threshold factor value) and units availability enhancement (for example, by choosing proper maintenance policy). This paper shows a method of incorporating information about units' availability into a procedure for determining the optimal system parameters. It also presents a method for determining indices that measure importance of voting units availability for both types of systems. These indices indicate voting units for which efforts of availability enhancement are the most beneficial from the entire system reliability improvement point of view.The approach is based on using a universal generating function technique and optimization procedure presented in [5]. Examples are presented. 相似文献
97.
Ki Su Kim Hyemin Kim Yunji Park Won Ho Kong Seung Woo Lee Sheldon J. J. Kwok Sei Kwang Hahn Seok Hyun Yun 《Advanced functional materials》2016,26(15):2512-2522
Vaccines are commonly administered by injection using needles. Although transdermal microneedles are less invasive promising alternatives, needle‐free topical vaccination without involving physical damage to the natural skin barrier is still sought after as it can further reduce needle‐induced anxiety and is simple to administer. However, this long‐standing goal has been elusive since the intact skin is impermeable to most macromolecules. Here, we show an efficient, noninvasive transdermal vaccination by employing two key innovations: the use of hyaluronan (HA) as vaccine carriers and non‐ablative laser adjuvants. Conjugates of a model vaccine ovalbumin (OVA) and HA—HA–OVA conjugates—induced more effective maturation of dendritic cells in vitro, compared to OVA. Following topical administration in the skin, HA–OVA conjugates penetrated into the epidermis and dermis in murine and porcine skins, as revealed by intravital microscopy and fluorescence assay. Topical administration of HA‐OVA conjugates significantly elevated both humoral and mucosal antibodies, with peak levels at four weeks. An OVA challenge at week eight elicited strong immune‐recall responses. With pretreatment of the skin using non‐ablative fractional laser beams as adjuvant, strong immunization was achieved with much reduced doses of HA–OVA (1 mg kg–1 OVA). Our results demonstrate the potential of the noninvasive patch‐type transdermal vaccination platform. 相似文献
98.
Hyun Soo Kim 《Computer aided design》2009,41(1):47-591
This paper presents n-dimensional feature recognition of triangular meshes that can handle both geometric properties and additional attributes such as color information of a physical object. Our method is based on a tensor voting technique for classifying features and integrates a clustering and region growing methodology for segmenting a mesh into sub-patches. We classify a feature into a corner, a sharp edge and a face. Then, finally we detect features via region merging and cleaning processes. Our feature detection shows good performance with efficiency for various dimensional models. 相似文献
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S. Appavu alias Balamurugan Ramasamy Rajaram 《Expert systems with applications》2009,36(10):12113-12119
This paper deals with some improvements to rule induction algorithms in order to resolve the tie that appear in special cases during the rule generation procedure for specific training data sets. These improvements are demonstrated by experimental results on various data sets. The tie occurs in decision tree induction algorithm when the class prediction at a leaf node cannot be determined by majority voting. When there is a conflict in the leaf node, we need to find the source and the solution to the problem. In this paper, we propose to calculate the Influence factor for each attribute and an update procedure to the decision tree has been suggested to deal with the problem and provide subsequent rectification steps. 相似文献
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在多通道余度系统的研究和应用中,同步问题是整个余度系统正确运行的基本保证。基于多交叉通道模型和同步时间的静态分配策略,提出动态时间容错方法。针对该方法,设计基于时间容错的动态表决控制算法,实现多通道系统中的动态同步。给出动态同步表决控制逻辑,用于控制表决时间并监测表决数据。理论分析和实验结果表明,时间容错的动态表决控制算法扩展了任务处理的时间窗口,与静态同步算法相比,可有效降低通道故障率,提高对瞬时干扰的抵御能力以及余度系统的可靠性。 相似文献