An environmental flow method applied in small and medium-sized mountainous rivers

In small and medium-sized mountainous rivers, there are usually hydropower stations in upper reaches as well as widened and heightened river sections in downstream reaches that are close to settlements. The environmental flow (EF) ensures river connectivity and the survival of aquatic organisms. The Tennant and wetted perimeter methods were used to calculate the minimum EF, and the R2CROSS criteria were used to evaluate the rationality of hydraulic parameters. The result shows that downstream areas with large cross-sections may suffer from shallow water depths, insufficient wetted perimeters, and poor overall connectivity of the water bodies, even under the standard EF discharges. A novel method was proposed to ensure EF and sustain suitable hydraulic conditions. The minimum EF calculated by the Tennant method is adopted as the design flow, and a small trapezoidal trough channel is excavated on the wide riverbed of an artificial river section. The width and depth of the small channel are calculated with Manning's equation. As a study case, this method was applied in the Fenglingang River in Zhejiang Province of China. A trapezoidal groove with a depth of 0.74 m and a bottom width of 0.52 m was excavated in the center of Fenglingang River to sustain EF and maintain river connectivity. This small channel not only prevents the river from cutoff, but also enables the water depth and wetted perimeter to meet the demand of aquatic organisms.     

Automatic Channel Detection Using DNN on 2D Seismic Data

Geologists interpret seismic data to understand subsurface properties and subsequently to locate underground hydrocarbon resources. Channels are among the most important geological features interpreters analyze to locate petroleum reservoirs. However, manual channel picking is both time consuming and tedious. Moreover, similar to any other process dependent on human intervention, manual channel picking is error prone and inconsistent. To address these issues, automatic channel detection is both necessary and important for efficient and accurate seismic interpretation. Modern systems make use of real-time image processing techniques for different tasks. Automatic channel detection is a combination of different mathematical methods in digital image processing that can identify streaks within the images called channels that are important to the oil companies. In this paper, we propose an innovative automatic channel detection algorithm based on machine learning techniques. The new algorithm can identify channels in seismic data/images fully automatically and tremendously increases the efficiency and accuracy of the interpretation process. The algorithm uses deep neural network to train the classifier with both the channel and non-channel patches. We provide a field data example to demonstrate the performance of the new algorithm. The training phase gave a maximum accuracy of 84.6% for the classifier and it performed even better in the testing phase, giving a maximum accuracy of 90%.     

放电故障紫外检测系统及其状态识别方法

紫外成像检测技术是一种检测高压设备故障的新方法;在此技术上研究设计了一种放电故障紫外检测系统,该系统能对实时采集的紫外图像进行相关的技术处理,同时可对故障点进行准确定位;根据数据建立了设备状态模型并提出一种基于人工神经网络的状态识别方法,应用MATLAB工具进行神经网络的设计和模拟,仿真结果达到预期效果;该系统可以准确地诊断设备的故障和运行状况,有较好运用前景和理论意义。     

Optimal tracking performance of MIMO discrete‐time systems with communication constraints

The optimal tracking problem for multiple‐input multiple‐output linear‐time‐invariant discrete‐time systems with communication constraints in the feedback path is studied in this paper. The tracking performance is measured by the energy of the error signal between the output of the plant and the reference signal. The objective is to obtain an optimal tracking performance, attainable by all possible stabilizing compensators. It is shown that the optimal tracking performance consists of two parts, one depends on the nonminimum phase zeros and zero direction of the given plant, as well as the reference input signal direction, and the other depends on the nonminimum phase zeros, unstable poles, and pole direction of the given plant, as well as the bandwidth and additive white Gaussian noise of the communication channel. It is also shown that, if the constraint of the communication channel does not exist, the optimal tracking performance reduces to the existing tracking performance of the control system without communication constraints. A typical example is given to illustrate the theoretical results. Copyright © 2011 John Wiley & Sons, Ltd.     

基于单幅图像景深和大气散射模型的去雾方法

为恢复雾天图像对比度和颜色,更好地提取图像中的信息,根据海上开阔海域的特点,利用3维到2维透视投影模型,推导了海上图像任意像素点景深的计算公式,并结合暗原色先验知识,有效解决基准景深点的选取和天空亮度的选取问题,最后基于相对景深模型和大气散射模型,对单幅雾天图像进行清晰化处理。通过大量雾天降质图像的实验验证,该算法的去雾效果优于基于暗原色先验统计方法的效果。     

Annexin 1 Is a Component of eATP-Induced Cytosolic Calcium Elevation in Arabidopsis thaliana Roots

Extracellular ATP (eATP) has long been established in animals as an important signalling molecule but this is less understood in plants. The identification of Arabidopsis thaliana DORN1 (Does Not Respond to Nucleotides) as the first plant eATP receptor has shown that it is fundamental to the elevation of cytosolic free Ca²⁺ ([Ca²⁺]_cyt) as a possible second messenger. eATP causes other downstream responses such as increase in reactive oxygen species (ROS) and nitric oxide, plus changes in gene expression. The plasma membrane Ca²⁺ influx channels involved in eATP-induced [Ca²⁺]_cyt increase remain unknown at the genetic level. Arabidopsis thaliana Annexin 1 has been found to mediate ROS-activated Ca²⁺ influx in root epidermis, consistent with its operating as a transport pathway. In this study, the loss of function Annexin 1 mutant was found to have impaired [Ca²⁺]_cyt elevation in roots in response to eATP or eADP. Additionally, this annexin was implicated in modulating eATP-induced intracellular ROS accumulation in roots as well as expression of eATP-responsive genes.     

Refining Genotypes and Phenotypes in KCNA2-Related Neurological Disorders

Pathogenic variants in KCNA2, encoding for the voltage-gated potassium channel K_v1.2, have been identified as the cause for an evolving spectrum of neurological disorders. Affected individuals show early-onset developmental and epileptic encephalopathy, intellectual disability, and movement disorders resulting from cerebellar dysfunction. In addition, individuals with a milder course of epilepsy, complicated hereditary spastic paraplegia, and episodic ataxia have been reported. By analyzing phenotypic, functional, and genetic data from published reports and novel cases, we refine and further delineate phenotypic as well as functional subgroups of KCNA2-associated disorders. Carriers of variants, leading to complex and mixed channel dysfunction that are associated with a gain- and loss-of-potassium conductance, more often show early developmental abnormalities and an earlier onset of epilepsy compared to individuals with variants resulting in loss- or gain-of-function. We describe seven additional individuals harboring three known and the novel KCNA2 variants p.(Pro407Ala) and p.(Tyr417Cys). The location of variants reported here highlights the importance of the proline(405)–valine(406)–proline(407) (PVP) motif in transmembrane domain S6 as a mutational hotspot. A novel case of self-limited infantile seizures suggests a continuous clinical spectrum of KCNA2-related disorders. Our study provides further insights into the clinical spectrum, genotype–phenotype correlation, variability, and predicted functional impact of KCNA2 variants.     

Permissive Modulation of Sphingosine-1-Phosphate-Enhanced Intracellular Calcium on BKCa Channel of Chromaffin Cells

Sphingosine-1-phosphate (S1P), is a signaling sphingolipid which acts as a bioactive lipid mediator. We assessed whether S1P had multiplex effects in regulating the large-conductance Ca²⁺-activated K⁺ channel (BK_Ca) in catecholamine-secreting chromaffin cells. Using multiple patch-clamp modes, Ca²⁺ imaging, and computational modeling, we evaluated the effects of S1P on the Ca²⁺-activated K⁺ currents (I_K(Ca)) in bovine adrenal chromaffin cells and in a pheochromocytoma cell line (PC12). In outside-out patches, the open probability of BK_Ca channel was reduced with a mean-closed time increment, but without a conductance change in response to a low-concentration S1P (1 µM). The intracellular Ca²⁺ concentration (Ca_i) was elevated in response to a high-dose (10 µM) but not low-dose of S1P. The single-channel activity of BK_Ca was also enhanced by S1P (10 µM) in the cell-attached recording of chromaffin cells. In the whole-cell voltage-clamp, a low-dose S1P (1 µM) suppressed I_K(Ca), whereas a high-dose S1P (10 µM) produced a biphasic response in the amplitude of I_K(Ca), i.e., an initial decrease followed by a sustained increase. The S1P-induced I_K(Ca) enhancement was abolished by BAPTA. Current-clamp studies showed that S1P (1 µM) increased the action potential (AP) firing. Simulation data revealed that the decreased BK_Ca conductance leads to increased AP firings in a modeling chromaffin cell. Over a similar dosage range, S1P (1 µM) inhibited I_K(Ca) and the permissive role of S1P on the BK_Ca activity was also effectively observed in the PC12 cell system. The S1P-mediated I_K(Ca) stimulation may result from the elevated Ca_i, whereas the inhibition of BK_Ca activity by S1P appears to be direct. By the differentiated tailoring BK_Ca channel function, S1P can modulate stimulus-secretion coupling in chromaffin cells.     

Regulation of Neutrophil Functions by Hv1/VSOP Voltage-Gated Proton Channels

The voltage-gated proton channel, Hv1, also termed VSOP, was discovered in 2006. It has long been suggested that proton transport through voltage-gated proton channels regulate reactive oxygen species (ROS) production in phagocytes by counteracting the charge imbalance caused by the activation of NADPH oxidase. Discovery of Hv1/VSOP not only confirmed this process in phagocytes, but also led to the elucidation of novel functions in phagocytes. The compensation of charge by Hv1/VSOP sustains ROS production and is also crucial for promoting Ca²⁺ influx at the plasma membrane. In addition, proton extrusion into neutrophil phagosomes by Hv1/VSOP is necessary to maintain neutral phagosomal pH for the effective killing of bacteria. Contrary to the function of Hv1/VSOP as a positive regulator for ROS generation, it has been revealed that Hv1/VSOP also acts to inhibit ROS production in neutrophils. Hv1/VSOP inhibits hypochlorous acid production by regulating degranulation, leading to reduced inflammation upon fungal infection, and suppresses the activation of extracellular signal-regulated kinase (ERK) signaling by inhibiting ROS production. Thus, Hv1/VSOP is a two-way player regulating ROS production. Here, we review the functions of Hv1/VSOP in neutrophils and discuss future perspectives.     

基于动态模式分解的移动用户信道容量预测算法

在多输入多输出环境下,为了能够连续预测出移动用户的信道容量并以此合理地分配用户资源,提出了一种基于动态模式分解（DMD）的信道容量预测方法及其优化方法：基于经验模态分解的选择性归一化动态模式分解（ESN-DMD）.仿真结果表明,DMD算法只适用于预测低移速低复杂度的用户信号,ESN-DMD算法可以预测不同移速的用户信道容量.