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对高校图书馆参考咨询服务的探讨   总被引:2,自引:0,他引:2  
面对现代信息时代的挑战,高校图书馆参考咨询服务进行着深刻的变革,其系统化、网络化、合作化、社会化、高效化是这种变革的集中体现。  相似文献   
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Surface opening cracks are common defects in large civil structures like bridges. They allow penetration of water or other agents that result in loss of durability earlier than expected. Their repair can be conducted by the injection of epoxy material that seals the crack sides keeping out any aggressive substances in addition to the recovery of strength. In order to evaluate crack parameters before impregnation as well as to determine the final repair effectiveness, a combination of Rayleigh and longitudinal waves is applied. Rayleigh waves demonstrate the filling condition of the material into the shallow layer near the surface while tomography using longitudinal waves through the thickness yields information about the area inside the structure. Wave propagation dispersion features are exploited by the proposed tomography at different frequencies, demonstrating that higher frequencies lead to more accurate characterization.  相似文献   
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The addition of superplasticizers is an important approach to prepare high performance cement-based materials. The effect of polynaphthalene series superplasticizer (PNS) and polycarboxylate type superplasticizer (PC) on early-age cracking and volume stability of cement-based materials was investigated by means of multi-channel ellipse ring shrinkage cracking test, free shrinkage and strength test. The general effect of PNS and PC is to increase initial cracking time of mortars, and decrease cracking sensitivity of mortars. As for decreasing cracking sensitivity of mortars, PC > H-UNF (high-thickness-type PNS) > C-UNF (common-thickness-type PNS). To incorporate superplasticizers is apparently to increases free shrinkage of mortars when keeping the constant W/B ratio and the content of cement pastes. As for the effect of controlling volume stability of mortars, PC > C-UNF > H-UNF. Maximum crack width of mortars with PC is lower, but the development rate of maximum crack width of mortars with H-UNF is faster in comparison with control mortars. Flexural and compressive strength of mortars and concretes at 28 days increased with increasing superplasticizer dosages under drying conditions. C-UNF was approximate to H-UNF, but PC was superior to PNS in the aspect of increasing strength of cement-based materials.  相似文献   
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In order to study the influence of depth-thickness ratio on bedding slope stability, whose sliding surface is flexural concave in shape under mining conditions, this paper aims to study the characteristics of deformation and damage of bedding sliding with depth-thickness ratios of 200:1, 150:1, 120:1, 100:1 and 50:1by adopting numerical simulation analysis software combined with laboratory-made ‘‘under the influence of mining variable sliding surface slope similar simulation test bed", and to propose identification methods for slope stability under the influence of mining. The results show that mining activities under the slope reduce slope stability. With a decrease in the mining depth ratio, the influence of mining on the slope increases gradually, and the damage to the slope gradually expands, the stability of the slope gradually reduces, fracture occurs on the slope toe and the central fissure gradually develops to the surface,and reaches slide threshold when the depth-thickness ratio is 50:1.  相似文献   
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Various molecular docking software packages are available for modeling interactions between small molecules and proteins.However,there have been few reports of modeling the interactions between metal ions and metalloproteins.In this study,the AutoDock package was employed to example docking into a di-iron binding protein,bacterioferritin.Each binding site of this protein was tested for docking with iron ions.Blind docking experiments showed that all docking conformations converged into two clusters,one for internal iron binding in sites within the metalloprotein and the other for external iron binding on the protein surface.Local docking experiments showed that there were significant differences between two internal iron binding sites.Docking at one site gave a reasonable root-mean-square deviation(RMSD) distribution with relatively low binding energy.Analysis of the binding mode quality for this site revealed that more than half of the docking conformations were categorized as having good binding geometry,while no good conformations were found for the other site.Further investigations indicated that coordinating water molecules contributed to the stability of binding geometries.This study provides an empirical approach towards the study of molecular docking in metalloproteins.  相似文献   
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Sun  Kaili  Li  Yuan  Zhang  Huyin  Guo  Chi  Yuan  Linfei  Hu  Quan 《The Journal of supercomputing》2022,78(14):16529-16552
The Journal of Supercomputing - In the literature, most previous studies on English implicit inter-sentence relation recognition only focused on semantic interactions, which could not exploit the...  相似文献   
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