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Macromolecular crystal structure determination can be complicated or brought to a halt by crystal imperfections. These issues motivated us to write up what we affectionately call ‘The Definitive Hitchhiker’s Guide to Pathological Macromolecular Crystals: Lattice Disorders and Modulations’. Perhaps the most challenging imperfections are lattice order–disorder phenomena and positional modulations. Many of these types of crystals have been solved, and progress has been made on the more challenging forms. Diagnostic tools and how to solve many of these problem crystal structures are reviewed. New avenues are provided for approaching the solution of incommensurately modulated crystals. There are a good number of case studies in the literature of lattice order–disorder phenomena and crystallographic modulations that make it timely to write a review. This review concludes with a projected pathway for solving incommensurately modulated crystals, personal views of future directions and needs of the crystallographic community.  相似文献   
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Mineral resources are fundamental to human well being and the development of the European society. Of particular importance are the construction minerals, namely sand and gravel, which are the basis of infrastructure development. More than 3 billion tonnes of sand, gravel (and crushed stone) are produced annually to meet the demands of the European building industry. Mineral extraction in Europe has become more difficult over the years due to increasing concerns for the environment and the lack of appreciation of the importance of the extractive industries for economic development. The challenge for sustainability is to find a balance between securing minerals supply, protecting the environment and achieving social progress.  相似文献   
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Training and continuous education is today for the management of a mineral producing operation more important than ever before. The focus of education today in the field of mineral producing industry has not only to be dedicated versus the needs of the industry but also versus the importance of the ever increasing need of societal acceptance of industrial operations. Therefore it is expected that graduates from mining schools not only have a good knowledge of technical and economical subjects but also a good background for the realisation of environmental and safety targets for the people at work and in the neighbourhood of an operation. A strong request to the education and training at university level is therefore not only to deliver a broad knowledge but also the formation of a basis which allows to obtain authority for functions as “safety expert”, “Mine rescuer”, “waste disposal expert” and others. In the text the contents of the BSc study program “Natural resources” are reviewed and the training and education for a “Natural Resources Manager” together with the required continuous education is discussed.  相似文献   
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The paper reviews the problems encountered with groundwater in surface mining in Scotland. The problems which occur at various stages of the mining process from initial exploration to mine planning and final restoration are referred to. Special consideration is given to mine drainage and pumping methods.  相似文献   
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Journal of Mining Science -  相似文献   
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