Ice/metal interfaces: fracture energy and fractography

Results are presented of the fracture tests of ice/metal interfaces in an attempt to utilize fracture mechanics to characterize the failure of ice/solid adhesion. The four-point bending delamination specimen was used to measure the fracture energy of ice/aluminium and ice/steel joints at — 15 °C. The interfacial fracture energy was found to be dependent on ice type and formation procedure of the ice/metal composites. Crack growth was in a manner of asymmetrical bursting, and both cohesive and adhesive failure mechanisms were observed. Although the fracture of ice/metal interfaces was brittle in nature, the evidence of dislocation slip in ice crystals, as revealed by etching and replicating, suggests that microplastic deformations occur in the ice component.     

Sleep-induced breathing instability. University of Wisconsin-Madison Sleep and respiration Research Group

We present a view of the neuromechanical regulation of breathing and causes of breathing instability during sleep. First, we would expect transient increases in upper airway resistance to be a major cause of transient hypopnea. This occurs in sleep because a hypotonic upper airway is more susceptible to narrowing and because the immediate excitatory increase in respiratory motor output in response to increased loads is absent in non-REM sleep. Secondly, sleep predisposes to an increased occurrence of ventilatory "overshoots", in part because abruptly changing sleep states cause transient changes in upper airway resistance and in the gain of the respiratory controller. Following these ventilatory overshoots, breathing stability will be maintained if excitatory short-term potentiation is the prevailing influence. On the other hand, apnea and hypopnea will occur if inhibitory mechanisms dominate following the ventilatory overshoot. These inhibitory mechanisms include: a) hypocapnia-if transient, will inhibit carotid chemoreceptors and cause hypopnea, but if prolonged will inhibit medullary chemoreceptors and cause apnea; b) a persistent inhibitory effect from lung stretch; c) baroreceptor stimulation, from a transient rise in systemic blood pressure immediately following termination of apnea or hypopnea may partially suppress the accompanying hyperpnea; d) depression of central respiratory motor output via prolonged brain hypoxia. Once apneas are initiated, reinitiation of inspiration is delayed even though excitatory stimuli have risen well above their apneic thresholds, and these prolonged apneas are commonly accompanied by tonic EMG activation of expiratory muscles of the chest wall and upper airway.     

Cross-sectional investigation of task demands and musculoskeletal discomfort among restaurant wait staff

A cross-sectional study of task demands and musculoskeletal discomfort among a sample of 100 wait staff in ten casual dining restaurants was conducted. In addition to answering a questionnaire about musculoskeletal discomfort and symptoms experienced in the past 12 months and attributed to work, subjects were asked about various aspects of their jobs, such as shift length, number of shifts per week and safety training. The managers of the restaurants were also interviewed to gather basic information on factors such as work hours, alternative duty availability and safety practices. When asked to rank the three most important causes of injuries, the responses of both managers and wait staff were congruent with Bureau of Labor Statistics (USA) data for 1999 on the nature of injuries and attributed exposures, with slips and falls, musculoskeletal disorders and acute injuries (e.g. burns, cuts) highlighted. Of the 100 subjects, 42% reported experiencing musculoskeletal symptoms in the past year, with the lower back area (18%) and shoulder (11%) with the most frequent symptoms reported in the responses. Although many of the materials handling tasks were not excessive, the heavier tray lifts and carries are a cause for concern. There are also slip and fall issues that influence the risks of these tasks. Future research needs, including addressing the mismatch between more common materials handling assessment tools and the nature of food serving tasks, are discussed.     

On the evolution of task-based analysis of manual materials handling, and its applicability in contemporary ergonomics

The industrial revolution significantly changed the way work was organized and analyzed by the introduction and widespread implementation of the division of labor philosophy. This philosophy has continued to dominate work design, and has evolved beyond the factory to include many facets of service industries, and even professional occupations. The analysis of manual work, particularly materials handling tasks, remains an active domain of ergonomics research and practice. Many of the task-analytic tools used for workplace analysis are rooted in the philosophy of dividing work into elements, analyzing the individual elements, and synthesizing the results into conclusions about the entire job, including the risk of contracting musculoskeletal disorders (MSDs). The authors discuss the notion that the nature of modern work, which is characterized by multiple tasks in a complex time pattern, and the complex nature of MSDs, which are influenced by biomechanical as well as psychological, political, and economic factors, may limit the effectiveness of classical task analytic techniques in preventing MSDs.     

In situ Sea Ice Experiments in McMurdo Sound: Cyclic Loading, Fracture, and Acoustic Emissions

The breakup of first-year sea ice plays an important role in the dynamics and thermodynamics of polar ice covers. A recent research program has studied the in situ mechanical properties of the annual ice in Antarctica to support the development of physically based models of the breakup process. As part of this effort, two field trips were conducted to McMurdo Sound, and the present paper describes the experimental work and presents selected results. The in situ experiments investigated the constitutive and fracture behavior of edge-notched, square plate specimens of first-year ice and involved a detailed characterization of the physical properties and thermal state of the ice. Acoustic emissions, which are generated by microcracking, were monitored in the crack tip vicinity and provide insight regarding the size of the process zone. The paper describes the physical properties and microstructure of the sheet, the cyclic-loading response, and the acoustic emissions activity from an extensive series of experiments conducted on one of the in situ specimens. Varying the cyclic-loading frequency and amplitude provided a means to examine rate effects on the anelastic and viscous components of strain and the extent of microcracking near the crack tip. The viscous deformation rate estimated from the experiments exhibited an increasing power-law exponent with values between one and three. Acoustic emissions monitoring indicated that microcracking occurred in a process zone near the crack tip, and the size of the process zone increased with decreasing cyclic loading frequency. Practical aspects of the experiments are considered, and the results are put into context with the overall modeling goals of the project.     

On the role of power in the design of materials handling tasks

The safety and productivity of workers engaged in materials handling has been a topic of interest to industrial engineers and ergonomists for some time. One of the fundamental questions that has generated considerable research is that of how to define and measure material handling capacity. The potential role of human muscle power and the resultant capacity to exert power on an external load as a measure of materials handling capacity is explored. Aside from applied literature in the exercise and sports science disciplines supporting this notion, a more theoretical basis is provided by the muscle physiology and morphology literature. The further empirical investigation of power as a means of defining materials handling capacity is supported.     

Evaluation of the ability of power to predict low frequency lifting capacity

An experiment was conducted to examine the role that maximal lifting power has in predicting maximum acceptable weight of lift (MAWL) for a frequency of one lift per 8 h. The secondary aim of the study was to compare the ability of power to predict MAWL to previously used measures of capacity including two measures of isometric strength, five measures of isokinetic strength, and isoinertial capacity on an incremental lifting test. Twenty-five male subjects volunteered to participate in the experiment. The isometric tests involved maximum voluntary contractions for composite lifting strength at vertical heights of 15 and 75 cm. Peak isokinetic strength was measured at velocities of 0.1, 0.2, 0.4, 0.6 and 0.8 m s-1 using a modified CYBEX II isokinetic dynamometer. Isoinertial lifting capacity was measured on the X-factor incremental lifting machine and peak power was measured on the incremental lifting machine by having subjects lift a 25 kg load as quickly as possible. The results indicate that peak isoinertial power is significantly correlated with MAWL, and this correlation was higher than any of the correlations between the other predictor variables and MAWL. The relationships between the isokinetic strength measures and MAWL were stronger than the relationships between the isometric measures and MAWL. Overall, the results suggest that tests used to predict MAWL should be dynamic rather than static.     

Thrombopoietin and its receptor, c-mpl, are constitutively expressed by mouse liver endothelial cells: evidence of thrombopoietin as a growth factor for liver endothelial cells

Present data suggest that the primary site of thrombopoietin (TPO) mRNA is the liver. Previously, we reported that specific murine liver endothelial cells (LEC-1) located in the hepatic sinusoids support in vitro megakaryocytopoiesis from murine hematopoietic stem cells suggesting that these cells may be a source of TPO. We report here that TPO and its receptor, c-mpl, are coexpressed on cloned LEC-1. Enzyme-linked immunosorbent assay (ELISA), biological assay, and flow cytometry studies confirmed the expression of both TPO and its receptor, respectively, at the protein level. TPO activity was enhanced in supernatants from LEC-1 treated with tumor necrosis factor (TNF)-alpha and gamma-interferon (INF). Our results show that TPO through its receptor stimulated the growth of LEC-1 in vitro. These observations establish LEC-1 as a novel source of TPO in the liver. To our knowledge, this is the first report that liver endothelial cells express both TPO and its receptor, c-mpl, and our findings indicate that this cytokine constitutes a growth factor for liver endothelial cells in vitro.     

Micropatterning of Electrospun Polyurethane Fibers Through Control of Surface Topography

A novel technique was developed to control the deposition of electrospun polyurethane fibers using a silicone collector substrate patterned with soft lithography. This method can be used to control selective fiber deposition with broad pattern dimensions (50–500 µm) over a large area. The combination of ease of use, low cost, tunability, and generation of relatively large fiber mats available with this technique is expected to advance our ability to mimic the orientation and anisotropic properties of native tissues to generate improved tissue engineering scaffolds.