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1.
Duan  Yongrui  Ge  Yao  Feng  Yixuan 《Electronic Commerce Research》2022,22(2):539-559
Electronic Commerce Research - We consider a platform providing free content for users and earning profit from the sale of advertising. The platform can collect and analyze personal data to...  相似文献   
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Small interfering RNA (siRNA) can effectively silence target genes through Argonate 2 (Ago2)-induced RNA interference (RNAi). It is very important to control siRNA activity in both spatial and temporal modes. Among different masking strategies, photocaging can be used to regulate gene expression through light irradiation with spatiotemporal and dose-dependent resolution. Many different caging strategies and caging groups have been reported for light-activated siRNA gene silencing. Herein, we describe a novel caging strategy that increases the blocking effect of RISC complex formation/process through host/guest (including ligand/receptor) interactions, thereby enhancing the inhibition of caged siRNA activity until light activation. This strategy can be used as a general approach to design caged siRNAs for the photomodulation of gene silencing of exogenous and endogenous genes.  相似文献   
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Mitigating gibbsite particle cracking and breakage during industrial alumina production can increase the quality of smelter grade alumina product by reducing the ultrafine particle content. Therefore, it is essential to investigate the particle cracking during static calcination and the breakage of calcined gibbsite particles under external force. In this work, we investigated the impact of the calcination ramping rate and the crystallite size on gibbsite particle cracking during static calcination. A slow ramping rate and a large pristine crystallite size tend to increase particle cracking. Apart from the study of particle cracking behaviour, we also investigated the breakage of calcined gibbsite particle under external force. Cracks on the particle surface can initiate breakage within the crystallite and along the grain boundary under external force. The breakage within crystallite occurs as the cleavage of the crystallite, while the breakage along the grain boundary leads to the shedding of a whole crystallite. We further explored the factors influencing the strength of calcined gibbsite particles. With increasing calcination temperature, the strength of particle increases when gibbsite converts to boehmite, and then decreases when boehmite converts into amorphous alumina. Particles containing smaller crystallites and calcined with fast ramping rates exhibit higher resistance to breakage.  相似文献   
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Polyethylene oxide (PEO)-polypropylene oxide (PPO)-polyethylene oxide block copolymer having different molecular weights are used as precursors of carbon materials to prepare Hollow -Derivatives carbon material as an electrocatalyst through block copolymer self-assembly. The composition and microstructure of the prepared catalysts are shown by Raman spectroscopy, X-ray diffraction (XRD), Test of nitrogen adsorption and desorption curves, High resolution transmission electron microscopy (HR-TEM) and scanning electron microscopy (HR-SEM). Oxygen was passed into alkaline electrolyte solution until the solution reached saturation state. With molecular weight increasing, the obtained sample gradually changed from block to hollow and spherical. When the molecular weight was 12600 g mol?1, the evenly hollow carbon nanocages was acquired (C-12600). In O2 saturated alkaline electrolyte (0.1 M KOH solution), C-12600's limited current density,half-wave potential and initial potential are 5.23 mA cm?2@0.4 V, 0.72 V and 0.81 V, respectively. And most important is that half-wave potential and onset potential have barely change after 2000 cycles of cyclic voltammetry. As a result, the porous carbon materials exhibited excellent electrocatalytic activity while maintaining high stability in alkaline KOH solution.  相似文献   
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胡章芳  张力  黄丽嘉  罗元 《计算机应用》2019,39(8):2480-2483
针对目前运动想象脑电(EEG)信号识别率较低的问题,考虑到脑电信号蕴含着丰富的时频信息,提出一种基于时频域的卷积神经网络(CNN)运动想象脑电信号识别方法。首先,利用短时傅里叶变换(STFT)对脑电信号的相关频带进行预处理,并将多个电极的时频图组合构造出一种二维时频图;然后,针对二维时频图的时频特性,通过一维卷积的方法设计了一种新颖的CNN结构;最后,通过支持向量机(SVM)对CNN提取的特征进行分类。基于BCI数据集的实验结果表明,所提方法的平均识别率为86.5%,优于其他传统运动想象脑电信号识别方法;同时将该方法应用在智能轮椅上,验证了其有效性。  相似文献   
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International Journal of Information Security - Data integrity is a critical security issue in cloud storage. The data integrity checking schemes by a third-party auditor (TPA) have attracted a lot...  相似文献   
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