In situ measurements of human cough aerosol hygroscopicity

The airborne dynamics of respiratory droplets, and the transmission routes of pathogens embedded within them, are governed primarily by the diameter of the particles. These particles are composed of the fluid which lines the respiratory tract, and is primarily mucins and salts, which will interact with the atmosphere and evaporate to reach an equilibrium diameter. Measuring organic volume fraction (OVF) of cough aerosol has proved challenging due to large variability and low material volume produced after coughing. Here, the diametric hygroscopic growth factors (GF) of the cough aerosol produced by healthy participants were measured in situ using a rotating aerosol suspension chamber and a humidification tandem differential mobility analyser. Using hygroscopicity models, it was estimated that the average OVF in the evaporated cough aerosol was 0.88 ± 0.07 and the average GF at 90% relative humidity (RH) was 1.31 ± 0.03. To reach equilibrium in dry air the droplets will reduce in diameter by a factor of approximately 2.8 with an evaporation factor of 0.36 ± 0.05. Hysteresis was observed in cough aerosol at RH = ∼35% and RH = ∼65% for efflorescence and deliquescence, respectively, and may depend on the OVF. The same behaviour and GF were observed in nebulized bovine bronchoalveolar lavage fluid.     

Mechanics of plain-woven fabrics for inflated structures

Pressurized fabric tubes, pressure-stabilized beams (known as air beams) and air-inflated structures are considered to be valuable technologies for lightweight, rapidly deployable structures. Design optimization of an inflated structure depends on a thorough understanding of woven fabric mechanics. In this paper the bending response of woven pressure-stabilized beams have been experimentally tested and analytically investigated. Additionally, the micromechanical effects of interacting tows have been studied through finite element models containing contact surfaces and nonlinear slip/stick conditions. Local unit cell models consisting of pairs of woven tows were created to characterize the effective constitutive relations. The material properties from the unit cell models were then used for the global continuum model subjected to 4-point flexure. An experimental set-up was designed and manufactured for testing of Vectran and PEN air beams. The air beam mid-span deflections were measured as functions of inflation pressure and bending load. Plots of the elastic and shear moduli with respect to the pressure and coefficient of friction have been generated. It was determined that the effective elastic and shear moduli were functions of inflation pressure, the material used and the geometry of the weave. It was shown that pneumatic or pressurized tube structures differ fundamentally from conventional metal structures.     

The effect of skull-pin insertion on cerebrospinal fluid pressure and cerebral perfusion pressure: influence of sufentanil and fentanyl

Directed delivery and distribution of anaesthetics (novocaine, lidocaine, trimecaine) immobilized on finely dispersed iron powders under the influence of an external magnetic field in body tissues of test animals have been studied. The data of emission spectral analysis relating to concentration of iron in soft and bone tissues of animals influenced by constant and alternating magnetic field on front and reverse sides over a period from 0 to 180 min are given.     

Analytical Modeling of Short-Channel Fully-Depleted Triple Work Function Metal Gate (TWFMG) SOI MESFET

Silicon - In this paper, a new structure: triple work function metal gate SOI MESFET, intended for integration into the deep-submicron CMOS technology, is proposed. The gate of the device consists...     

Experimental determination of gas holdup and volumetric mass transfer coefficient in a jet bubbling reactor

The hydrodynamics and mass transfer characteristics of a lab-scale jet bubbling reactor(JBR) including the gas holdup, volumetric mass transfer coefficient and specific interfacial area were assessed experimentally investigating the influence of temperature, p H and superficial gas velocity. The reactor diameter and height were 11 and 30 cm,respectively. It was equipped with a single sparger, operating at atmospheric pressure, 20 and 40℃, and two p H values of 3 and 6. The height of the liquid was 23 cm, while the superficial gas velocity changed within 0.010–0.040 m·s~(-1) range. Experiments were conducted with pure oxygen as the gas phase and saturated lime solution as the liquid phase. The liquid-side volumetric mass transfer coefficient was determined under unsteady-state oxygen absorption in a saturated lime solution. The gas holdup was calculated based on the liquid height change, while the specific interfacial area was obtained by a physical method based on the bubble size distribution(BSD) in different superficial gas velocities. The results indicated that at the same temperature but different p H, the gas holdup variation was negligible, while the liquid-side volumetric mass transfer coefficient at the p H value of 6 was higher than that at the p H = 3. At a constant p H but different temperatures, the gas holdup and the liquid-side volumetric mass transfer coefficients at 40℃ were higher than that of the same at 20℃. A reasonable and appropriate estimation of the liquid-side volumetric mass transfer coefficient(kla) in a pilot-scale JBR was provided which can be applied to the design and scale-up of JBRs.     

Real-time embedded emotional controller

Recent studies show that emotion is a mechanism for fast decision-making in human and other animals. Mathematical models have been developed for describing emotion in mammals. These models, similar to other bioinspired models, must be implemented in embedded platforms for industrial and real applications. In this paper, brain emotional learning based intelligent controller, which is based on mammalian middle brain, is designed and implemented on field-programmable gate arrays, and this emotional controller is applied for controlling of laboratorial overhead traveling crane in model-free and embedded manner. The main features of this controller are leaning capability, providing a model-free control algorithm, robustness and the ability to respond swiftly. By designing appropriate stress signals, a designer can implement a proper trade among control objectives.     

Reliability-based robust Pareto design of linear state feedback controllers using a multi-objective uniform-diversity genetic algorithm (MUGA)

In this paper, fuzzy threshold values, instead of crisp threshold values, have been used for optimal reliability-based multi-objective Pareto design of robust state feedback controllers for a single inverted pendulum having parameters with probabilistic uncertainties. The objective functions that have been considered are, namely, the normalized summation of rising time and overshoot of cart (S_RO–C) and the normalized summation of rising time and overshoot of pendulum (S_RO–P) in the deterministic approach. Accordingly, the probabilities of failure of those objective functions are also considered in the reliability-based design optimization (RBDO) approach. A new multi-objective uniform-diversity genetic algorithm (MUGA) is presented and used for Pareto optimum design of linear state feedback controllers for single inverted pendulum problem. In this way, Pareto front of optimum controllers is first obtained for the nominal deterministic single inverted pendulum using the conflicting objective functions in time domain. Such Pareto front is then obtained for single inverted pendulum having probabilistic uncertainties in its parameters using the statistical moments of those objective functions through a Monte Carlo simulation (MCS) approach. It is shown that multi-objective reliability-based Pareto optimization of the robust state feedback controllers using MUGA with fuzzy threshold values includes those that may be obtained by various crisp threshold values of probability of failures and, thus, remove the difficulty of selecting suitable crisp values. Besides, the multi-objective Pareto optimization of such robust feedback controllers using MUGA unveils some very important and informative trade-offs among those objective functions. Consequently, some optimum robust state feedback controllers can be compromisingly chosen from the Pareto frontiers.     

A memetic algorithm for minimizing the total weighted completion time on a single machine under step-deterioration

In this paper, we consider minimizing total weighted completion time criteria on a single machine. Jobs processing times are step function of its starting time and all jobs have a common due date. First, we present some new lemmas and dominance properties for this NP-hard problem, and then a memetic algorithm using these properties is developed. We compare the solutions of the memetic algorithm with optimal solutions obtained from complete enumeration. The results show that the average percentage error of the proposed algorithm from optimal solutions is about 2% and as the variance of processing time increase, the percentage errors decrease.