全文获取类型
收费全文 | 75篇 |
免费 | 3篇 |
专业分类
电工技术 | 1篇 |
化学工业 | 40篇 |
金属工艺 | 1篇 |
能源动力 | 1篇 |
轻工业 | 15篇 |
一般工业技术 | 1篇 |
冶金工业 | 17篇 |
自动化技术 | 2篇 |
出版年
2024年 | 1篇 |
2018年 | 2篇 |
2015年 | 1篇 |
2013年 | 3篇 |
2010年 | 1篇 |
2009年 | 3篇 |
2008年 | 3篇 |
2007年 | 1篇 |
2006年 | 1篇 |
2005年 | 1篇 |
2003年 | 3篇 |
2002年 | 2篇 |
2001年 | 2篇 |
1999年 | 2篇 |
1998年 | 11篇 |
1997年 | 7篇 |
1996年 | 4篇 |
1995年 | 2篇 |
1994年 | 4篇 |
1993年 | 3篇 |
1992年 | 1篇 |
1991年 | 4篇 |
1990年 | 3篇 |
1989年 | 4篇 |
1987年 | 2篇 |
1985年 | 1篇 |
1984年 | 1篇 |
1980年 | 1篇 |
1979年 | 1篇 |
1976年 | 3篇 |
排序方式: 共有78条查询结果,搜索用时 15 毫秒
1.
LC Rump E Schwertfeger U Schaible G Fraedrich P Schollmeyer 《Canadian Metallurgical Quarterly》1994,74(3):434-440
BACKGROUND: Cultures of epidermal cells are commonly used to study skin biology and differentiation. Recently a method to culture nail matrix cells has been established. OBJECTIVE: We report the biologic characteristics of nail matrix cells in vitro compared with those of epidermal keratinocytes. METHODS: Human nail matrix cells were isolated and cultured in defined medium. Electron-microscopic examination, growth rate, integrin expression and keratin synthesis pattern were evaluated. In addition, the cells were cultured in serum-containing medium. RESULTS: Nail matrix cells appear to be larger than human epidermal keratinocytes and, at the ultrastructural level, they contain a higher euchromatin/heterochromatin ratio and a lower nucleus/cytoplasm ratio and have a higher growth rate. The synthesis of "hard" keratins was detected at all calcium concentrations. Immunofluorescence analyses showed the expression of alpha 2, alpha 3, and alpha 6 integrin subunits. When cultured in serum-containing medium, nail matrix cells produced an outgrowth of epithelium and a spontaneous migration phenomenon associated with a tendency to stratify in a semilunar area that resembles the architecture of the nail matrix. The pluristratified epithelium showed characteristic markers of nail differentiation. CONCLUSION: Culture of nail matrix cells may represent a useful model to study the biologic properties of nail structure, alterations in some nail diseases and the effects of drugs. 相似文献
2.
计算流体力学模拟可检测拉幅干燥机内的气体流动过程,并对喷嘴指板后端和通风机上端潜在的问题区域进行检测。蒸发过程的模拟表明,织物表面温度与水分的分布不均匀。然而,由于缺乏设备对实验模拟数据进行认征,故无法判断其可靠性。 相似文献
3.
KP Maier H Talke G Hoppe-Seyler J Fr?hlich P Schollmeyer G Sch?nbach KP Erhart W Gerok 《Canadian Metallurgical Quarterly》1976,54(21):1021-1025
Enzymes of the Krebs-Henseleit urea-cycle were localized by means of differential centrifugation and fractional tissue extraction in rat liver and in human liver. Argininosuccinatlyase (ASAL) and Argininosuccinatsynthetase (ASAS) represent enzymes of the soluble cytoplasmic fraction. Ornithine-ketoacid-transaminase(OKT), carbamyl-phosphate-synthetase (CPS) and ornithine-carbamyl-transferase (OCT) are localized in the mitochondrial and nuclei fractions of the liver cell. Most of the arginase activity is bound to subcellular structures (probably to nuclei). A small portion of arginase-activity was found in the soluble cytoplasmatic fraction. The enzymes of the Krebs-Henseleit urea-cycle are equally distributed in rat liver and in human liver. Differences in the subcellular localisation of (mitochondrial) enzymes in human liver could be attributed to mitochondrial breakage during tissue preparation and do not represent in-vivo conditions. 相似文献
4.
It is shown in this paper, that during laser treatment of polymeric materials the occurrence of discolouring layers of laser crack deposits onto the substrate can be avoided without preventing the formation of a laser-induced microstructuring of the surface. Using water, alcohols, ethers or aqueous surfactant solutions as impregnating media during laser treatment a high degree of whiteness of fabrics can be maintained. 相似文献
5.
无机-有机混聚物涂层产业用纺织品 总被引:2,自引:0,他引:2
无机-有机混聚物具有改进和创建表面性能的巨大潜力。使用溶胶-凝胶技术可以生产多种涂层材料,并且可以把不同的性能综合利用。考虑到许多产业用织物有在恶劣气候条件下使用的要求,这些混聚物可以提高纺织材料的竞争力。这些涂层可以有效地防护聚酰胺纤维和玻璃纤维材料在酸碱环境下的水解。对玻璃纤维织物,这种防护还可以起到提高耐磨性的效果。在另外一些研究中,本文作者叙述了制备疏油、疏水、着色、光致变色涂层或透明涂层的可能性,其中使用溶胶-凝胶技术制备的透明涂层具有很高的紫外吸收性能。 相似文献
6.
A Kr?mer-Guth T Quaschning H Pavenst?dt J Galle M Nauck MW Baumstark P Schollmeyer W M?rz C Wanner 《Canadian Metallurgical Quarterly》1997,12(7):1336-1343
BACKGROUND: Recent studies suggest that dyslipidaemia accelerates the progression of diabetic nephropathy, but the various pathomechanisms underlying such abnormalities are not completely delineated. METHODS: We isolated, radiolabelled, and characterized very-low-density lipoproteins (VLDL) and low-density lipoproteins (LDL) from eight diabetic patients with moderate impairment of renal function and dyslipidaemia and studied their interaction with LDL receptors in human glomerular epithelial cells. RESULTS: While diabetic VLDL showed no compositional changes, LDL particles contained a higher proportion of triglycerides at the expense of cholesterol in comparison with healthy controls. Despite differences in composition, both VLDL and LDL from patients exhibited reduced receptor affinity and cellular uptake capacity by glomerular epithelial cells. Since LDL composition was altered intracellular cholesterol homeostasis was investigated. Due to reduced cholesterol content and lower uptake capacity, diabetic LDL were less effective in suppressing intracellular sterol synthesis and in activating acylcholesterol acyltransferase than LDL from controls. Electrophoretic mobility of apoB from diabetic patients was enhanced as compared to controls, most probably due to the higher degree of glycation (17 + 1.7 versus 11 + 1%, P < 0.05) but not to oxidation (TBARS 0.5 + 0.2 versus 0.2 + 0.1 mumol/1). Oxidized LDL was not taken up in significant amounts, indicating no scavenger receptor activity in glomerular epithelial cells. CONCLUSION: The receptor-specific uptake of diabetic VLDL and LDL by glomerular epithelial cells is impaired. Compositional changes of the LDL particle and glycation of the protein moiety may contribute to altered glomerular uptake. However, glycation of the protein moiety may be superior to compositional changes. Because glomerular structures like mesangial matrix and endothelial cells are known for preferential binding of modified lipoproteins, further studies are required to elucidate their potential role in the progression of diabetic glomerulosclerosis. 相似文献
7.
Thomas Bahners Uwe Schlosser Eckhard Schollmeyer 《Solar Energy Materials & Solar Cells》2008,92(12):1661-1667
Concepts of technical fibers following models for the polar bear hair to be used for textile solar collectors are discussed. The approach to coat fibers with a thin layer into which fluorescent dyestuff was dispersed was studied experimentally. Modified fibers made of different polymers were characterized with respect to optical properties relevant for the bionic model. In the case of poly(methylmethacrylate) fibers, the envisaged effect could be achieved to high efficiency. The optical performance could be enhanced by ultrasonic dispersion of the dyestuff in the coating matrix. The effect is less significant in semi-crystalline fibers such as poly(ethylene terephthalate), which is attributed to diffuse scattering. 相似文献
8.
K Sch?fer RR Schumann S St?teknuel P Schollmeyer GJ Dobos 《Canadian Metallurgical Quarterly》1998,13(4):969-974
BACKGROUND: Bacterial peritonitis is a frequent complication during treatment of end-stage renal failure by continuous ambulatory peritoneal dialysis. Local host defence mechanisms including the secretion of proinflammatory cytokines by peritoneal macrophages are of particular importance in the pathogenesis of infectious complications. LPS-binding protein (LBP) and soluble CD14 (sCD14) are serum factors known to regulate the endotoxin-induced cellular immune response. However, it is still unknown whether LBP and sCD14 are also present in the peritoneal effluent of CAPD patients. METHODS: Using specific immunoassays, we examined the concentration of LBP, sCD14 and the proinflammatory cytokines TNF-alpha, IL-1beta and IL-6 in the dialysis effluents of 31 patients with CAPD-associated peritonitis. Twenty patients without peritonitis served as controls. Intraperitoneal LPS concentrations were determined using the limulus amebocyte lysate assay. RESULTS: Bacterial lipopolysaccharide could be detected in 42% of the infected dialysis effluents. In comparison to controls (0.2 +/- 0.05 microg/ml), LBP was significantly elevated in both gram-negative/LPS-positive (1.03 +/- 0.3 microg/ml) and gram-positive infections (0.5 +/- 0.14 microg/ml) (P<0.05). No significant differences were detected concerning the intraperitoneal sCD14 levels in the three patient groups. Levels of TNF-alpha, IL-1beta and IL-6 were significantly increased in the effluents of patients with bacterial peritonitis compared to noninfected controls. Moreover the respective cytokine concentrations were significantly higher in the gram-negative/LPS-positive compared to the gram-positive bacterial infections (P<0.01). CONCLUSION: Our data demonstrate that LBP is significantly elevated in the dialysis effluents of patients with CAPD-associated peritonitis caused by both gram-negative and gram-positive bacteria and might be used as a marker of intraperitoneal infection. Moreover, our findings support the concept that LBP enhances the effects of LPS on cytokine production by peritoneal macrophages. The function of LBP in gram-positive infection remains to be further elucidated. 相似文献
9.
10.