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1.
Aluminum has been reported to inhibit long-term potentiation (LTP) following in vivo administration and decrease glutamate release following in vitro exposure. Because glutamate release is critical for synaptic transmission and the development and maintenance of LTP in the hippocampus, we examined the effects of aluminum chloride (AlCl3) on depolarization-induced glutamate release and LTP in rat hippocampal slices. The effects of AlCl3 on [14C]glutamate release were examined by incubation of slices in depolarizing (56 mM)K+ buffer solution in the absence or presence of 2 mM CaCl2. After 15 min depolarization, AlCl3 (100-1000 microM) did not significantly affect Ca(2+)-dependent [14C]glutamate release from slices, whereas a known Ca2+ channel blocker (100 microM CdCl2) decreased Ca(2+)-dependent [14C]glutamate release by approximately 50%. In contrast to a previous report, acute exposure to AlCl3 was without effect on depolarization-dependent glutamate release. LTP of the population spike (PS) in CA1 of hippocampus was induced by the delivery of stimulus trains to the stratum radiatum. LTP of the PS was observed in both control slices and slices bathed in solution containing 100 microM AlCl3. Neither the magnitude nor longevity (measured up to 1 h posttrain) of LTP distinguished control from aluminum-exposed slices. The lack of sensitivity in rat to the encephalopathic changes induced by aluminum, or methodological differences in exposure conditions may account for the lack of effect of aluminum on in vitro LTP in rat hippocampus. 相似文献
2.
Zaffar Mubariz Garg Sourav Milford Michael Kooij Julian Flynn David McDonald-Maier Klaus Ehsan Shoaib 《International Journal of Computer Vision》2021,129(7):2136-2174
International Journal of Computer Vision - Visual place recognition (VPR) is the process of recognising a previously visited place using visual information, often under varying appearance... 相似文献
3.
Meraj Talha Rauf Hafiz Tayyab Zahoor Saliha Hassan Arslan Lali M. IkramUllah Ali Liaqat Bukhari Syed Ahmad Chan Shoaib Umar 《Neural computing & applications》2021,33(17):10737-10750
Neural Computing and Applications - Lung cancer is a deadly disease if not diagnosed in its early stages. However, early detection of lung cancer is a challenging task due to the shape and size of... 相似文献
4.
A multilayer background modeling technique is presented for video surveillance. Rather than simply classifying all features in a scene as either dynamically moving foreground or long-lasting, stationary background, a temporal model is used to place each scene object in time relative to each other. Foreground objects that become stationary are registered as layers on top of the background layer. In this process of layer formation, the algorithm deals with ”fake objects” created by moved background, and noise created by dynamic background and moving foreground objects. Objects that leave the scene are removed based on the occlusion reasoning among layers. The technique allows us to understand and visualize a scene with multiple objects entering, leaving, and occluding each other at different points in time. This scene understanding leads to a richer representation of temporal scene events than traditional foreground/background segmentation. The technique builds on a low-cost background modeling technique that makes it suitable for embedded, real-time platforms. 相似文献
5.
中国加入WTO后,中国洗涤用品行业面临着新的机遇与挑战,中国洗涤用品市场将面临更加激烈的竞争。由于环保的呼声越来越高,中国已开始在部分地区禁磷。中国洗涤用品工业将如何发展,其前景如何,专家的看法又如何,就这些问题本刊专访了有关人士。 相似文献
6.
Limited bandwidth resources lead to a number of challenges especially for eHealth applications, which are communicated over IP and wireless networks. These multimedia services include high-resolution videos and have very large file sizes that require a high level of compression to overcome this limitation. Therefore, there is an acute demand for the research community to provide an efficient multimedia framework to encode medical videos with high quality specifically under the conditions of an error-prone environment. Both an affordable delivery framework and effective coding techniques are extremely desirable for the delivery of high-quality eHealth video applications for transmission over heterogeneous networks and devices. In this paper, we propose and demonstrate a multimedia framework to support eHealth applications, which has an improved coding scheme that uses an SVC-scalable extension of MPEC-4 AVC/H.264. Simulation results show that the proposed scheme achieves a significant improvement in terms of the PSNR-Y gain and reduces the picture quality degradation caused by artifacts and distortions, compared to the existing scheme. 相似文献
7.
Raja Muhammad Asif Zahoor Naz Hira Shoaib Muhammad Mehmood Ammara 《Neural computing & applications》2022,34(7):5771-5790
Neural Computing and Applications - In the present study, a novel application of backpropagated neurocomputing heuristics (BNCH) is presented for epidemic virus model that portrays the Stuxnet... 相似文献
8.
Adnan Abid Naveed Hussain Kamran Abid Farooq Ahmad Muhammad Shoaib Farooq Uzma Farooq Sher Afzal Khan Yaser Daanial Khan Muhammad Azhar Naeem Nabeel Sabir 《Neural computing & applications》2016,27(5):1207-1229
The quantity of information placed on the web has been greater than before and is increasing rapidly day by day. Searching through the huge amount of data and finding the most relevant and useful result set involves searching, ranking, and presenting the results. Most of the users probe into the top few results and neglect the rest. In order to increase user’s satisfaction, the presented result set should not only be relevant to the search topic, but should also present a variety of perspectives, that is, the results should be different from one another. The effectiveness of web search and the satisfaction of users can be enhanced through providing various results of a search query in a certain order of relevance and concern. The technique used to avoid presenting similar, though relevant, results to the user is known as a diversification of search results. This article presents a survey of the approaches used for search result diversification. To this end, this article not only provides a technical survey of existing diversification techniques, but also presents a taxonomy of diversification algorithms with respect to the types of search queries. 相似文献
9.
Software Quality Journal - 相似文献
10.
Arwa Ishaq A. Khayyat Seema Zargar Tanveer A. Wani Muneeb U. Rehman Azmat Ali Khan 《International journal of molecular sciences》2022,23(10)
Atrazine (ATR) is a herbicide globally used to eliminate undesired weeds. Herbicide usage leads to various adverse effects on human health and the environment. The primary source of herbicides in humans is the food laced with the herbicides. The ATR binding to trypsin (TYP) was investigated in this study to explore its binding potential and toxicity. In vitro interaction of ATR with TYP was studied using multi-spectroscopic methods, molecular docking, and enzyme kinetics to explore the mechanism of binding for the TYP-ATR system. The TYP-ATR complex revealed binding constants (103 M−1), suggesting a moderate binding. The free energy for the TYP-ATR complexes was negative, suggesting a spontaneous interaction. Thermodynamic parameters enthalpy (ΔH) and entropy (ΔS) obtained positive values for the TYP-ATR system suggesting hydrophobic interactions in the binding process. Micro-environmental and conformational changes in TYP molecules were induced on interaction with ATR. Reduced catalytic activity of TYP was observed after interaction with ATR owing to the changes in the secondary structure of the TYP. 相似文献