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Kenneth Train 《Energy》1985,10(12):1243-1253
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DS Berman R Hachamovitch H Kiat I Cohen JA Cabico FP Wang JD Friedman G Germano K Van Train GA Diamond 《Canadian Metallurgical Quarterly》1995,26(3):639-647
OBJECTIVES: This study assessed the incremental prognostic implications of normal and equivocal exercise technetium-99m (Tc-99m) sestamibi single-photon emission computed tomography (SPECT) and sought to determine its incremental prognostic value, impact on patient management and cost implications. BACKGROUND: The prognostic implications of Tc-99m sestamibi SPECT are not well defined, and risk stratification using this test has not been explored. METHODS: We studied 1,702 patients referred for exercise Tc-99m sestamibi SPECT who were followed up for a mean (+/- SD) of 20 +/- 5 months. Patients with previous percutaneous transluminal coronary angioplasty or coronary artery bypass surgery were excluded. The SPECT studies were assessed using semiquantitative visual analysis. Cardiac death and myocardial infarction were considered "hard" events, and coronary angioplasty and bypass surgery > 60 days after testing were considered "soft" events. RESULTS: Of the 1,702 patients studied, 1,131 had normal or equivocal scan results. A total of 10 events occurred in this group (1 cardiac death and 1 myocardial infarction [0.2% hard events]; 4 coronary angioplasty and 4 bypass surgery procedures [0.7% soft events]). The rates of hard events and referral to catheterization after SPECT were similarly low in patients with a low (< 0.15), intermediate (0.15 to 0.85) and high (> 0.85) post-exercise treadmill test (ETT) likelihood of coronary artery disease. With respect to scan type, patients with normal, probably normal or equivocal scan results had similarly low hard event rates. In the 571 patients with abnormal scan results, there were 43 hard events (7.5%) and 42 soft events (7.4%) (p < 0.001 vs. 1,131 patients with normal scan results for both). When the complete spectrum of scan responses was considered, SPECT provided incremental prognostic value in all patient subgroups analyzed. However, the nuclear scan was cost-effective only in patients with interpretable exercise ECG responses and an intermediate to high post-ETT likelihood of coronary artery disease and in those with uninterpretable exercise ECG responses and an intermediate to high pre-ETT likelihood of coronary artery disease. CONCLUSIONS: Normal or equivocal exercise Tc-99m sestamibi study results are associated with a benign prognosis, even in patients with a high likelihood of coronary artery disease. Although incremental prognostic value is added by nuclear testing in all patient subgroups, a testing strategy incorporating nuclear testing proved to be cost-effective only in the groups with an intermediate to high likelihood of coronary artery disease before scanning. 相似文献
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J. Schwaibold H. Schade W. Kundrat K. Raible und G. Train 《Zeitschrift für Lebensmitteluntersuchung und -Forschung A》1955,100(1):79-80
Ohne Zusammenfassung 相似文献
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B Benari H Kiat J Erel M Hyun FP Wang C Williams JD Friedman G Germano KF Van Train D Berman 《Canadian Metallurgical Quarterly》1995,2(6):478-484
Bacterial antibodies were studied in acute, intermediate and convalescent phase sera (mean duration from first to last sample 36 days) of 121 children hospitalized for acute lower respiratory tract infection. Antibody responses were observed in 45% of all cases and in 29% of the 21 children < 1 year old. A total of 15 responses to Streptococcus pneumoniae (pneumolysin), 20 to Haemophilus influenzae, 9 to Moraxella catarrhalis, 3 to chlamydiae and 8 to Mycoplasma pneumoniae were found. In 79 patients with 4 consecutive samples available, 52% of the 31 responses were measurable within 5 days from admission. Overall the responses were not associated with upper respiratory tract bacterial findings or acute otitis media. Significantly more responses were found in the 121 children with acute lower respiratory tract infection than in healthy controls (P < 0.007). We conclude that bacterial antibody assays provide a useful tool in the study of the etiology of acute lower respiratory tract infection in young children, even if the interval between paired serum samples is short. 相似文献
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M. Rohrlich und G. Train 《Zeitschrift für Lebensmitteluntersuchung und -Forschung A》1954,99(5):346-351
Zusammenfassung Aus Haferschälkleie ist ein bitterschmeckendes Glucosid isoliert worden, das keine Saponineigenschaften hat. Sein Aglykon besitzt Steoridstruktur. Die Zuckerkomponente ist aus Rhamnose und Glucose im Verhältnis 1:2 zusammengesetzt.Die Arbeit wurde durch eine Sachbeihilfe der Deutschen Forschungsgemeinschaft in dankenswerter Weise geföert. 相似文献
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在250CONFORM连续挤压机上用雾化铝粉为原料较系统地试验研究了各种工艺参数对挤压制品性能及组织的影响。 相似文献
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The characteristics of the propagation process for the electroinitiated emulsion polymerisation of vinyl acetate are described when current is varied by a factor of 36 and emulsifier concentration by 128. The order with respect to current is 0.8, whilst with emulsifier concentration, two definite ranges are observed with exponents 0.26 and 1.12 at low and high concentrations respectively. A similar two range effect is observed using particle size measurements. Behaviour at low emulsifier concentration is similar to that described previously for vinyl acetate, involving particle formation mainly by precipitation from solution. At high emulsifier concentrations micelle formation appears to be of increased importance. 相似文献