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排序方式: 共有131条查询结果,搜索用时 31 毫秒
1.
Roberto Amadini Maurizio Gabbrielli Jacopo Mauro 《Annals of Mathematics and Artificial Intelligence》2016,76(1-2):229-246
Within the Constraint Satisfaction Problems (CSP) context, a methodology that has proven to be particularly performant consists of using a portfolio of different constraint solvers. Nevertheless, comparatively few studies and investigations have been done in the world of Constraint Optimization Problems (COP). In this work, we provide a generalization to COP as well as an empirical evaluation of different state of the art existing CSP portfolio approaches properly adapted to deal with COP. The results obtained by measuring several evaluation metrics confirm the effectiveness of portfolios even in the optimization field, and could give rise to some interesting future research. 相似文献
2.
This paper focuses on the problem of grasp stability and grasp quality analysis. An elegant way to evaluate the stability of a grasp is to model its wrench space. However, classical grasp quality measures suffer from several disadvantages, the main drawback being that they are not task related. Indeed, constructive approaches for approximating the wrench space including also task information have been rarely considered. This work presents an effective method for task-oriented grasp quality evaluation based on a novel grasp quality measure. We address the general case of multifingered grasps with point contacts with friction.The proposed approach is based on the concept of programming by demonstration and interactive teaching, wherein an expert user provides in a teaching phase a set of exemplar grasps appropriate for the task. Following this phase, a representation of task-related grasps is built. During task planning and execution, a grasp could be either submitted interactively for evaluation by a non-expert user or synthesized by an automatic planning system. Grasp quality is then assessed based on the proposed measure, which takes into account grasp stability along with its suitability for the task. To enable real-time evaluation of grasps, a fast algorithm for computing an approximation of the quality measure is also proposed. Finally, a local grasp optimization technique is described which can amend uncertainties arising in supplied grasps by non-expert users or assist in planning more valuable grasps in the neighborhood of candidate ones.The paper reports experiments performed in virtual reality with both an anthropomorphic virtual hand and a three-fingered robot hand. These experiments suggest the effectiveness and task relevance of the proposed grasp quality measure. 相似文献
3.
Enrico Mario Alessandro Fassi Mariangela Garofalo Jacopo Sgrignani Michele Dei Cas Matteo Mori Gabriella Roda Andrea Cavalli Giovanni Grazioso 《International journal of molecular sciences》2022,23(9)
(1) Background: Disfunctions in autophagy machinery have been identified in various conditions, including neurodegenerative diseases, cancer, and inflammation. Among mammalian autophagy proteins, the Atg8 family member GABARAP has been shown to be greatly involved in the autophagy process of prostate cancer cells, supporting the idea that GABARAP inhibitors could be valuable tools to fight the progression of tumors. (2) Methods: In this paper, starting from the X-ray crystal structure of GABARAP in a complex with an AnkirinB-LIR domain, we identify two new peptides by applying in silico drug design techniques. The two ligands are synthesized, biophysically assayed, and biologically evaluated to ascertain their potential anticancer profile. (3) Results: Two cyclic peptides (WC8 and WC10) displayed promising biological activity, high conformational stability (due to the presence of disulfide bridges), and Kd values in the low micromolar range. The anticancer assays, performed on PC-3 cells, proved that both peptides exhibit antiproliferative effects comparable to those of peptide K1, a known GABARAP inhibitor. (4) Conclusions: WC8 and WC10 can be considered new GABARAP inhibitors to be employed as pharmacological tools or even templates for the rational design of new small molecules. 相似文献
4.
Blasting in geological bodies is an industrial process acting in an environment characterized by high uncertainties (natural joints,faults,voids,abrupt structural changes),which are transposed into the... 相似文献
5.
Papichaya Chaisakul Mohamed-Said Rouifed Jacopo Frigerio Daniel Chrastina Jean-René Coudevylle 《Science and Technology of Advanced Materials》2014,15(1)
Electro-absorption from GeSi heterostructures is receiving growing attention as a high performance optical modulator for short distance optical interconnects. Ge incorporation with Si allows strong modulation mechanism using the Franz–Keldysh effect and the quantum-confined Stark effect from bulk and quantum well structures at telecommunication wavelengths. In this review, we discuss the current state of knowledge and the on-going challenges concerning the development of high performance GeSi electro-absorption modulators. We also provide feasible future prospects concerning this research topic. 相似文献
6.
Giovanni Pulci Jacopo Tirillò Francesco Marra Fabrizio Sarasini Alessandra Bellucci Teodoro Valente Cecilia Bartuli 《Metallurgical and Materials Transactions A》2014,45(3):1401-1408
Thermal sprayed MCrAlY coatings are widely used as a bond coat in thermal barrier systems to protect the substrate from corrosion and high temperature oxidation and to improve the compatibility between the ceramic top coat and metallic substrate. In this paper, the high temperature oxidation resistance of MCrAlY coatings with modified compositions was evaluated; in particular, the effect of the addition of reactive and refractory elements (Ta, Re, Si, and Hf) was investigated. MCrAlY coatings were obtained by high velocity oxygen fuel spray and vacuum plasma spray techniques; samples were exposed to air at 1423 K (1150 °C) and the oxidation kinetics were evaluated by measuring the thickness of the thermally grown oxide (TGO) scale at several exposure times. Experimental data confirmed that the oxidation resistance of MCrAlY coatings is strictly related to the amount of the reactive and refractory elements in the starting powders and that a thorough understanding of the microstructural modifications taking place during oxidation is essential for controlling TGO growth and thermal barriers’ durability. 相似文献
7.
Corrado Costa Paolo Menesatti Jacopo Aguzzi Stefano D’Andrea Francesca Antonucci Valentina Rimatori Federico Pallottino Marco Mattoccia 《Food and Bioprocess Technology》2010,3(1):43-48
The actual Italian production of clams is chiefly sustained by the native Tapes decussatus and the fortuitously imported Tapes philippinarum. Both species are commercialized as “Vongola verace”, but the commercial value of T. philippinarum is lower. The discrimination of species by sight is usually difficult and it cannot be done by observation based on shell
morphology but only when animals open their valves hence displaying the two siphons. In this study, we propose a new, noninvasive
method to discriminate individuals of both species based on the analysis of the external shape of their shells. Accordingly,
in sympatric populations at two sites of the Po river outlet, we have chosen individuals (63 for T. decussatus and 57 for T. philippinarum) of comparable commercial size for which a certain genetic discrimination was previously done. Pictures of the left side
valve were taken for all specimens. Their profiles were analyzed with the elliptic Fourier analysis. The mean outline for
each species was graphically extracted. The coefficients of the harmonic equations were analyzed by multivariate classification
(partial least squares discriminant analysis [PLSDA]). Results showed a high percentage of correct classification of individuals
of both species (96.6%). Contour analysis reflected the overall shell shape and thus identified morphological aspects that
were difficult to recognize and quantify in sight. The high percentage of correct classifications obtained by combining the
analysis of elliptic Fourier harmonics with PLSDA demonstrated the feasibility of this method to discriminate species with
a high level of resemblance. 相似文献
8.
Arcidiacono C Diolaiti E Tordi M Ragazzoni R Farinato J Vernet E Marchetti E 《Applied optics》2004,43(22):4288-4302
The Layer-Oriented Simulation Tool (LOST) is a numerical simulation code developed for analysis of the performance of multiconjugate adaptive optics modules following a layer-oriented approach. The LOST code computes the atmospheric layers in terms of phase screens and then propagates the phase delays introduced in the natural guide stars' wave fronts by using geometrical optics approximations. These wave fronts are combined in an optical or numerical way, including the effects of wave-front sensors on measurements in terms of phase noise. The LOST code is described, and two applications to layer-oriented modules are briefly presented. We have focus on the Multiconjugate adaptive optics demonstrator to be mounted upon the Very Large Telescope and on the Near-IR-Visible Adaptive Interferometer for Astronomy (NIRVANA) interferometric system to be installed on the combined focus of the Large Binocular Telescope. 相似文献
9.
10.
Raffaele Grasso Marco Cococcioni Baptiste Mourre John Osler Jacopo Chiggiato 《Expert systems with applications》2013,40(10):3886-3899
A decision support system for the optimal deployment of drifting acoustic sensor networks for cooperative track detection in underwater surveillance applications is proposed and tested on a simulated scenario. The system integrates sea water current forecasts, sensor range models and simple drifting buoy kinematic models to predict sensor positions and temporal network performance. A multi-objective genetic optimization algorithm is used for searching a set of Pareto optimal deployment solutions (i.e. the initial position of drifting sonobuoys of the network) by simultaneously optimizing two quality of service metrics: the temporal mean of the network area coverage and the tracking coverage. The solutions found after optimization, which represent different efficient tradeoffs between the two metrics, can be conveniently evaluated by the mission planner in order to choose the solution with the desired compromise between the two conflicting objectives. Sensitivity analysis through the Unscented Transform is also performed in order to test the robustness of the solutions with respect to network parameters and environmental uncertainty. Results on a simulated scenario making use of real probabilistic sea water current forecasts are provided showing the effectiveness of the proposed approach. Future work is envisioned to make the tool fully operational and ready to use in real scenarios. 相似文献