制备超细镍粉的研究进展

介绍了制备超细镍粉的主要方法，并对这些方法的制备过程、优缺点以及目前用这些方法制备的超细镍粉的情况进行了介绍．最后指出了存在的问题和未来的发展方向．     

液质联用技术分析精氨酸双糖苷对麦芽糖酶的抑制活性

Maltulosyl arginine is the initial maillard reaction product of maltose and arginine, which may have anti-diabetic activity. In this study, LC/MS was combined with ultrafiltration as a new method to investigate its inhibitory activity on maltase. The quantitative data was got from a triple quadrupole instrument in multiple reaction monitoring (MRM) mode. The experimental results proved that maltulosyl arginine is an effective maltase inhibitor and can be used for the treatment of diabetes and obesity.     

三聚氰胺的基质辅助激光解吸/电离飞行时间质谱分析

Oxidized carbon nanotubes are tested as the matrix for analysis of the melamine by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS). Traditional MALDI matrix are not suit for analysis of the low molecular compounds due to the interference associated to the matrix clusters. Oxidized carbon nanotubes can transfer energy to the analyte under the laser irradiation, which makes analyte well ionized or desorbed. Moreover, the interference of the intrinsic matrix ions can be eliminated. Melamine as the a toxic additive which had been added in the milk powder, then it is necessary to establish a new method for detection of the melamine rapid and sensitive.     

电感耦合等离子体质谱质量分馏效应产生机理研究

Mass discrimination mostly is an obstacle to accurate determination of inductively coupled plasma mass spectrometry (ICP-MS). It is the prevailing notion that mass bias in ICP-MS results from space-charge effects of high density ions form the behind of skimmer cone to the before of slot where a fraction of lighter isotopes fail to enter the mass analyzer. Neodymium isotopes was analyzed by a Nu Plasma multi-collector inductively coupled plasma mass spectrometer (MC-ICP-MS) to investigate the mass discrimination, respectively changing two crucial analytical parameters: the nebulizer flow and the x-coordinate of inductively coupled plasma, measuring the variety of the Ar40Ar40 molecular ions intensity and the exponential factor of mass discrimination. The curves indicate the presence of the secondly mechanism that lead to the heavier isotope depletion. It is maybe the plasma centrifuge effects, a concept proposed firstly by Qing-zhu Yin and Cin-Ty Lee. The two contrary mechanisms act on the ions and in theory the points should be exist where the two forces are equilibrium and the measurement results are the expectation values.     

金属离子与钙调蛋白相互作用的基质辅助激光解吸电离飞行时间质谱研究

Calmodulin is a ubiquitous calcium-binding protein in eukaryote cells and engages in various important biological pathways. In the present study, binding interactions between several metal ions and calmodulin were investigated by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). The results revealed that the specific binding of metal ions with the protein could be detected using MALDI-TOF MS.     

不同加工方法对人参皂苷转化的影响

Five different processed methods for ginseng were used to transferred ginsenosides with large molecule mass into low polar ginsenosides. The contents of low polar ginsenosides in these ginseng products were determined by ESI-MS. The results show that the high pressure steaming method make for increasing the concent of low polar ginsenosides, while soakage in vinegar is not good comparing with it.     

ESI-MS法研究白芍炮制前后化学成分的变化

ESI-MS analytical method was employed to study extracts of unprocessed and processed Radix Paeoniae alba. The results of the experiments prove that different processed methods is making a certain different influence on the contents of chemical components in Radix Paeoniae alba. This method is simple and accurate. It can be used for analyse of Traditional Chinese Medicine(TCM).     

利用高速逆流色谱和电喷雾质谱研究西洋参中皂苷

High-speed counter-current chromatography(HSCCC) and electrospray ionisation mass spectrometry (ESI-MS) were developed for the analysis the ginsenosides in plant, which were extracted from the root of Panax quinquefolium L.. ESI-MS experiment was carried out to aid the identification of three ginsenosides obtained in HSCCC by comparing the molecular weights and fragment ions of the molecular ion with that of the standard. It is a simple and quick analysis technology.     

醒酒玉米低聚肽的分离制备及其氨基酸序列分析

以脱淀粉玉米蛋白粉为原料,用Alcalase 2.4L在优化酶解条件下制得玉米低聚肽产品COP。通过体外醒酒活性及动物试验表明:COP具有较高体内外醒酒活性,同时发现COP的剂量与小鼠血醇含量的降低呈明显的剂量—效应关系。经凝胶过滤色谱和反相色谱分离分级及醒酒活性筛选,得到醒酒活性较强的玉米低聚肽级分COPⅢ-17。该级分通过超高效液相色谱—四级杆—飞行时间串联质谱联用分析,得到其氨基酸序列为:P-Y-L-P-L-L-P-S。     

600MW超临界锅炉调试重点环节控制分析

针对600MW超临界锅炉特点，分析介绍了机组调试过程中的重点环节，并提出各环节控制方法，为以后同类机组调试及运行提供了宝贵经验。