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1.
Angelika Varga Zoltn Mszr Mikls Sivad Tímea Bcskai Bence Vgh va Kkai Istvn Nagy Pter Szücs 《International journal of molecular sciences》2021,22(5)
The phosphorylation of serine 10 in histone 3 (p-S10H3) has recently been demonstrated to participate in spinal nociceptive processing. However, superficial dorsal horn (SDH) neurons involved in p-S10H3-mediated nociception have not been fully characterized. In the present work, we combined immunohistochemistry, in situ hybridization with the retrograde labeling of projection neurons to reveal the subset of dorsal horn neurons presenting an elevated level of p-S10H3 in response to noxious heat (60 °C), causing burn injury. Projection neurons only represented a small percentage (5%) of p-S10H3-positive cells, while the greater part of them belonged to excitatory SDH interneurons. The combined immunolabeling of p-S10H3 with markers of already established interneuronal classes of the SDH revealed that the largest subset of neurons with burn injury-induced p-S10H3 expression was dynorphin immunopositive in mice. Furthermore, the majority of p-S10H3-expressing dynorphinergic neurons proved to be excitatory, as they lacked Pax-2 and showed Lmx1b-immunopositivity. Thus, we showed that neurochemically heterogeneous SDH neurons exhibit the upregulation of p-S10H3 shortly after noxious heat-induced burn injury and consequential tissue damage, and that a dedicated subset of excitatory dynorphinergic neurons is likely a key player in the development of central sensitization via the p-S10H3 mediated pathway. 相似文献
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The article established the regularities of change of the physicomechanical characteristics and strength of glass textolites in single and repeated thermal loading. It shows that under multiple loading the intense loss of strength of the investigated materials is due to increased porosity on account of the large number of microcracks appearing in the structure. A correlation is obtained between the elastic and strength characteristics and porosity in dependence on the temperature of multiple heating which in the first approximation is described by a polynomial of second degree with respect to temperature, multiplied by the reciprocal of porosity.Translated from Problemy Prochnosti, No. 6, pp. 53–58, June, 1991. 相似文献
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Ér. V. Kal’yanov 《Technical Physics Letters》2007,33(6):451-453
A new simple model of a system with chaotic dynamics, based on the equations of bistable systems, is considered. The possibility of converting harmonic signals into chaotic oscillations, which represent intermittent irregular and switching quasi-regular motions, is demonstrated by numerical methods. The mechanism of chaotization is analyzed using the results of numerical calculations. 相似文献
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By measuring electroluminescence (EL) in barium titanate crystals exposed to a pulsed electric field in combination with a
magnetic field, we have studied the dependence of a shift in the temperature of maximum EL on the magnetic field strength
and on the mutual orientation of the electric and magnetic fields. The possible mechanisms of the observed effects are discussed. 相似文献
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G. T. Vigant A. B. Énglin N. N. Zakharova I. V. Klimyuk 《Chemistry and Technology of Fuels and Oils》1991,27(5):244-248
Translated from Khimiya i Tekhnologiya Topliv i Masel, No. 5, 11–13, May, 1991. 相似文献
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The properties of glasses of the lithium-aluminoborosilicate system were investigated, namely, the density, spreadability, thermal expansion, and nature of crystallized phases at various temperatures. A crystal-optical analysis was conducted. The glasses were used to prepare abrasive compositions. Their strength properties were studied as a function of the composition of the glass binder and the regime of heat treatment.Translated from Steklo i Keramika, No. 3, pp. 27–30, March, 1996. 相似文献