多孔β-TCP陶瓷药物载体的制备与体外释药速率的研究

本文用注浆成形的方法制备了以β-TCP为主晶相的多孔药物载体，体外测定了利福平的释药速率。实验结果表明，利福平在模拟体液中能够达到稳定的释放，可以作为骨结核手术后的辅助治疗。多孔β-TCP药物载体有望成为一种理想的药物缓释载体。     

多孔β-TCP陶瓷药物载体结构与性能的影响因素

本分析了影响多孔β-TCP陶瓷药物载体结构与性能的因素，确定了制备多孔β-TCP陶瓷药物载体的技术路线和工艺参数。     

β-磷酸三钙陶瓷的制备及应用

由于β-磷酸三钙陶瓷(β—TCP)具有良好的生物降解性、生物相容性和生物无毒性等优点,因而受到广大研究者的重视,目前已广泛应用于骨缺损修复、骨替代等方面。本文综述了近年来β—TCP陶瓷的制备工艺及其在骨科方面的应用。     

烟气脱硫系统运行参数对脱硫效率的数值模拟

采用数值模拟的方法分析了液滴初始粒径、烟气出入塔温度、烟气入塔速度、SO2入塔浓度和脱硫剂浓度等影响脱硫效率的敏感参数,建立了合理的数学模型,分析了上述参数在反应塔内的变化及其对脱硫效率的影响规律,确定了合理的参数调控体系。     

Preparation of nano-TiO2 by liquid hydrolysis and characterization of its antibacterial activity

The nano-TiO2 particles were prepared by liquid hydrolysis method and characterized using XRD. Its antibacterial activity against two representative bacterial, Escherichia coli and Staphylococcus aureus, was also studied. The experimental results showed that the nano-TiO2 calcinated at 600-700 ℃ contained the obvious anatase phase and exerted excellent antibacterial activity. The feature of antibacterial activity of nanoTiO2 was non-strains specificity and exerted best antibacterial activity at concentration of 0.8 g/L.     

微观分析在混凝土质量评价中的应用

建立了混凝土质量评价的模型和方法，计算出了粗、细骨料及水泥浆体在混凝土中所占的比例，并对水泥浆体的致密程度，孔结构及水化产物各类和形态进行了描述，为水泥混凝土的质量评价提供了科学依据。     

影响多孔β-TCP陶瓷释药速率的因素

本文通过改变粘结剂、成孔剂的含量和烧成温度,制得不同微观结构的多孔β-TCP陶瓷载体．以利福平为模型药物,测定不同载体的释药速率;取相同的载体,分别载长春新碱和利福平,比较不同药物对释药速率的影响。实验结果表明：载体的显气孔率越大,释药速率越大;药物的溶解性对释药速率也有影响。     

Effects of β-TCP Ceramics on Intracellular Ca~(2+) Concentration,Mineralization of Osteoblast and Protein Structure

β-TCP, as one of calcium phosphates ceramics, exerts perfect biocompatibility and osteoconductivity, and is clinically used as a bone graft substitute for decades. Consequently, the effects of β-TCP ceramics on intracellular Ca2+ concentration, mineralization of osteoblast and BSA protein structure were studied. Results showed that β-TCP could increase the intracelluar Ca2+ concentration and mineralization of osteoblast, indicating that β-TCP ceramics could take part in the organic metabolism and the degrad...     

Effects of β-TCP ceramics on osteoblast cellular proliferating, mineralization and osteocalcin expression

After co-cultrured osteoblast with β-TCP ceramics, the cellular proliferating, mineralization and osteocalcin expression were studied. MTT assay showed that β-TCP ceramics had no affect on cellular proliferating. Laser scanning confocal detection showed that β-TCP ceramics could increase the mineralization level of osteoblast. Furthermore, RT-PCR showed that β-TCP could increase the expression level of osteocalcin. Those results indicate β-TCP ceramics had perfect biocompatibility and increased the mineralization of osteoblast to accelerate osteogenesis by means of affecting the expression of genes involving in osteogeneticprocess.     

纳米氧化钛的凝胶网格制备及光催化性能研究

以氨水、三氯化钛为原料,明胶为反应介质,采用凝胶网格沉淀法制备锐钛矿型二氧化钛纳米粒子,并用XRD、SEM对产品进行了表征,探讨了部分反应条件对产品粒径的影响。实验确定最佳制备条件为:明胶含量为14%、Ti3+浓度为0.6 mol/L、NH3.H2O浓度为0.8 mol/L,所得产物粒度均匀、大小可控、不易团聚。采用光催化降解实验讨论了催化剂用量、光源、脱色时间等因素对直接耐晒翠蓝染料降解率的影响。TiO2投加量为8 g/L、高压汞灯光照1 h时,直接耐晒翠蓝脱色率可达84.17%。