Crack Stability and Its Effect on Fracture Toughness of Hot-Pressed Silicon Nitride Beam Specimens

The effect of stable crack extension on fracture toughness test results was determined using single-edge precracked beam specimens. Crack growth stability was examined theoretically for bars loaded in three-point bending under displacement control. The calculations took into account the stiffness of both the specimen and the loading system. The results indicated that the stiffness of the testing system played a major role in crack growth stability. Accordingly, a test system and specimen dimensions were selected which would result in unstable or stable crack extension during the fracture toughness test, depending on the exact test conditions. Hot-pressed silicon nitride bend bars (NC132) were prepared with precracks of different lengths, resulting in specimens with different stiffnesses. The specimens with the shorter precracks and thus higher stiffness broke without stable crack extension, while those with longer cracks, and lower stiffness, broke after some stable crack extension. The fracture toughness values from the unstable tests were 10% higher than those from the stable tests. This difference, albeit small, is systematic and is not considered to be due to material or specimen-to-specimen variation. It is concluded that instability due to the stiffness of test system and specimen must be minimized to ensure some stable crack extension in a fracture toughness test of brittle materials in order to avoid inflated fracture toughness values.     

Visual tracking using convolutional features with sparse coding

Artificial Intelligence Review - Visual object tracking has become one of the most active research topics in computer vision, and it has been applied in several commercial...     

Mental imagery classification using one-dimensional convolutional neural network for target selection in single-channel BCI-controlled mobile robot

Neural Computing and Applications - This paper introduces the use of the one-dimensional convolutional neural network (1D-CNN) for end-to-end EEG decoding with application towards a BCI system with...     

Differential Action of Connexin Hemichannel and Pannexin Channel Therapeutics for Potential Treatment of Retinal Diseases

Dysregulation of retinal function in the early stages of light-induced retinal degeneration involves pannexins and connexins. These two types of proteins may contribute to channels that release ATP, leading to activation of the inflammasome pathway, spread of inflammation and retinal dysfunction. However, the effect of pannexin channel block alone or block of both pannexin channels and connexin hemichannels in parallel on retinal activity in vivo is unknown. In this study, the pannexin channel blocker probenecid and the connexin hemichannel blocker tonabersat were used in the light-damaged rat retina. Retinal function was evaluated using electroretinography (ERG), retinal structure was analyzed using optical coherence tomography (OCT) imaging and the tissue response to light-induced injury was assessed immunohistochemically with antibodies against glial fibrillary acidic protein (GFAP), Ionized calcium binding adaptor molecule 1 (Iba-1) and Connexin43 (Cx43). Probenecid did not further enhance the therapeutic effect of connexin hemichannel block in this model, but on its own improved activity of certain inner retina neurons. The therapeutic benefit of blocking connexin hemichannels was further evaluated by comparing these data against results from our previously published studies that also used the light-damaged rat retina model. The analysis showed that treatment with tonabersat alone was better than probenecid alone at restoring retinal function in the light-damaged retina model. The results assist in the interpretation of the differential action of connexin hemichannel and pannexin channel therapeutics for potential treatment of retinal diseases.     

Effects of Solvent Exchange Period and Heat Treatment on Physical and Chemical Properties of Rice Husk Derived Silica Aerogels

In this study, hydrophobic silica aerogels were synthesized from rice husk ash-derived sodium silicate through sol-gel processing, solvent exchange, surface modification and ambient pressure drying. By volume, 10% of trimethylchlorosilane (TMCS) in 90% of n-hexane was used as a hydrophobic solution in the surface modification process. The physical and chemical properties of silica aerogels were characterized by density and porosity measurements, scanning electron microscopy (SEM), Fourier transforms infrared (FTIR) spectroscopy, Brunauer–Emmett–Teller theory (BET) and dynamic scanning calorimetry (DSC). The hydrogels prepared were in the form of 2.5 ± 0.5 mm beads and then converted into alcogels through solvent exchange with ethanol for repetition of 3, 6 and 9 days. It is found that the optimal quality of silica aerogels with the BET surface area as high as 668.82 m²/g was obtained from the alcogels of the solvent exchange period of 9 days. Depending on the size of the gel’s block, a longer solvent exchange period will ensure adequate removal of pore water. Post heat treatment on silica aerogels obtained from the 9 days of solvent exchange at 200, 300 and 400 °C for 2 h results in slight decreased of aerogel’s density from 0.048 g/cm³ to 0.039 g/cm³ and the hydrophobicity of the aerogels is decreased above 380 °C as confirmed by DSC analysis.

     

Silphinene Sesquiterpenes as Model Insect Antifeedants

Silphinene sesquiterpenes are established chrysomelid antifeedants. In this work, nine silphinene analogs, 11-acetoxy-5-angeloyloxysilphinen-3-one (1), 11-acetoxy-5-tigloyloxysilphinen-3-one (2), 11-acetoxy-5-iso- butyryloxysilphinen-3-one (3), 11-hydroxy-5-angeloyloxysilphinen-3-one (4), 11,5-dihydroxysilphinen-3-one (5), 11,5-diacetoxysilphinen-3-one (6), 5,11-diisobutyryloxysilphinen-3-one (7), silphinen-3,5,11-trione (8), and O-methyl-5-epicantabrenolic acid methyl ester (10), and a presilphiperfolane sesquiterpene (9) were tested against several divergent insect species, including the lepidopteran Spodoptera littoralis, the chrysomelid Leptinotarsa decemlineata, and five aphid species, and their antifeedant effects were compared with those of picrotoxinin, a GABA-antagonist, and thymol, an allosteric modulator for insect GABA receptors. All insects tested responded to at least one silphinene analog and/or GABA antagonist. Compound 3 and thymol were effective antifeedants against all species tested except S. littoralis, with varying potencies according to their feeding ecologies. The toxicity of these compounds was species-dependent and did not correlate with their antifeedant effect.     

Incorporation and distribution of saturated and unsaturated fatty acids into nuclear lipids of hepatic cells

Liver nuclear incorporation of stearic (18∶0), linoleic (18∶2n−6), and arachidonic (20∶4n−6) acids was studied by incubation in vitro of the [1-¹⁴C] fatty acids with nuclei, with or without the cytosol fraction at different times. The [1-¹⁴C] fatty acids were incorporated into the nuclei as free fatty acids in the following order: 18∶0>20∶4n−6≫18∶2n−6, and esterified into nuclear lipids by an acyl-CoA pathway. All [1-¹⁴C] fatty acids were esterified mainly to phospholipids and triacylglycerols and in a minor proportion to diacylglycerols. Only [1-¹⁴C] 18∶2n−6-CoA was incorporated into cholesterol esters. The incorporation was not modified by cytosol addition. The incorporation of 20∶4n−6 into nuclear phosphatidylcholine (PC) pools was also studied by incubation of liver nuclei in vitro with [1-¹⁴C]20∶4n−6-CoA, and nuclear labeled PC molecular species were determined. From the 15 PC nuclear molecular species determined, five were labeled with [1-¹⁴C]20∶4n−6-CoA: 18∶0–20∶4, 16∶0–20∶4, 18∶1–20∶4, 18∶2–20∶4, and 20∶4–20∶4. The highest specific radioactivity was found in 20∶4–20∶4 PC, which is a minor species. In conclusion, liver cell nuclei possess the necessary enzymes to incorporate exogenous saturated and unsaturated fatty acids into lipids by an acyl-CoA pathway, showing specificity for each fatty acid. Liver cell nuclei also utilize exogenous 20∶4n−6-CoA to synthesize the major molecular species of PC with 20∶4n−6 at the sn-2 position. However, the most actively synthesized is 20∶4–20∶4 PC, which is a quantitatively minor component. The labeling pattern of 20∶4–20∶4 PC would indicate that this molecular species is synthesized mainly by the de novo pathway.     

Effect of kinesthetic and tactile haptic feedback on the quality of experience of edutainment applications

Haptic technologies and applications have received enormous attention in the last decade. The incorporation of haptic modality into multimedia applications adds excitement and enjoyment to an application. It also adds a more natural feel to multimedia applications, that otherwise would be limited to vision and audition, by engaging as well the user’s sense of touch, giving a more intrinsic feel essential for ambient intelligent applications. However, the improvement of an application’s Quality of Experience (QoE) by the addition of haptic feedback is still not completely understood. The research presented in this paper focuses on the effect of haptic feedback and what it potentially adds to the experience of the user as opposed to the traditional visual and auditory feedback. In essence, it investigates certain issues regarding stylus-based haptic education applications and haptic-enhanced entertainment videos. To this end, we used two haptic applications: the haptic handwriting learning tool to experiment with force feedback haptic interaction and the tactile YouTube application for tactile haptic feedback. In both applications, our analysis shows that the addition of haptic feedback will increase the QoE in the absence of fatigue or discomfort for this category of applications. This implies that the incorporation of haptic modality (both force feedback as well as tactile feedback) has positively contributed to the overall QoE for the users.     

The Price of Anarchy in Network Creation Games Is (Mostly) Constant

We study the price of anarchy and the structure of equilibria in network creation games. A network creation game is played by n players {1,2,…,n}, each identified with a vertex of a graph (network), where the strategy of player i, i=1,…,n, is to build some edges adjacent to i. The cost of building an edge is α>0, a fixed parameter of the game. The goal of every player is to minimize its creation cost plus its usage cost. The creation cost of player i is α times the number of built edges. In the SumGame variant, the usage cost of player i is the sum of distances from i to every node of the resulting graph. In the MaxGame variant, the usage cost is the eccentricity of i in the resulting graph of the game. In this paper we improve previously known bounds on the price of anarchy of the game (of both variants) for various ranges of α, and give new insights into the structure of equilibria for various values of α. The two main results of the paper show that for α>273?n all equilibria in SumGame are trees and thus the price of anarchy is constant, and that for α>129 all equilibria in MaxGame are trees and the price of anarchy is constant. For SumGame this answers (almost completely) one of the fundamental open problems in the field—is price of anarchy of the network creation game constant for all values of α?—in an affirmative way, up to a tiny range of α.