Characterization,in vitro bioactivity and biological studies of sol-gel-derived TiO2 substituted 58S bioactive glass

Bioactive glasses (BGs) have been used for bone formation and bone repair processes in recent years. This study investigated the titanium substitution effect on 58S BGs (Ti-BGs) 60SiO₂-(36 − X)CaO-4P₂O₅-XTiO₂ (X = 0, 3, and 5 mol.%) prepared by the sol-gel technique, and the main goal was to find the optimum amount of titanium in Ti-BGs. Synthesized BGs, which were investigated after immersion in simulated body fluid (SBF), were tested by X-ray diffraction (XRD) analysis, Fourier transform infrared spectroscopy (FTIR), and scanning electron microscopy. Moreover alkaline phosphate (ALP) activity, 3-(4,5dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, and antibacterial studies were employed to investigate the biological properties of Ti-BGs. According to the FTIR and XRD test results, hydroxyapatite (HA) formation on Ti-BGs surfaces was confirmed. Meanwhile, the presence of 5 mol.% compared to 3 mol.% increased the HA grain distribution and their size on the Ti-BGs surface. Additionally, MTT and ALP results confirmed that the optimal amount of titanium substitution in BG was 5 mol.%. Since 5 mol.% Ti incorporated BG (BG-5) had the highest biocompatibility level, antibacterial properties, maximum cell proliferation, and ALP activity among the synthesized Ti-BGs, it is presented as the best candidate for further in vivo investigations.     

Berechnung der Wirbelstromdichten und-kräfte in der Umgebung großer supraleitender Spulen für den magnetischen Einschluß bei der Kernfusion

Übersicht Um die Betriebssicherheit großer supraleitender Magnetsysteme für die Kernfusionsforschung zu gewährleisten, muß die im Magnetsystem gespeicherte Energie schnell entladen werden können. Durch die veränderlichen großvolumigen Magnetfelder werden in benachbarten leitfähigen Strukturen durch Induktion hohe Wirbelströme hervorgerufen. Durch sie treten dort elektromagnetische Kräfte. auf, die einzelne Komponenten mechanisch überlasten können. Zur Berechnung dieser Kräfte wurde eine einfache numerischanalytische Methode entwickelt, die im folgenden vorgestellt und mit Finite-Elemente-Verfahren verglichen wird.

---

Calculation of eddy current densities and forces around large superconducting coils for nuclear fusion

Contents The reliable operation of the superconducting magnet systems used for the magnetic confinement in nuclear fusion research requires the ability of a fast discharge of the stored magnetic energy. The corresponding magnetic field variation gives rise to high eddy currents by inductive coupling with surrounding conductive components. The eddy current forces can lead to a mechanical overload of some of these components. A simple numerical-analytical method was developed in order to calculate these forces. This method is presented and compared with the Finite Element Method.

     

Swarm Intelligent Compressive Routing in Wireless Sensor Networks

This article proposes a novel algorithm to improve the lifetime of a wireless sensor network. This algorithm employs swarm intelligence algorithms in conjunction with compressive sensing theory to build up the routing trees and to decrease the communication rate. The main contribution of this article is to extend swarm intelligence algorithms to build a routing tree in such a way that it can be utilized to maximize efficiency, thereby rectifying the delay problem of compressive sensing theory and improving the network lifetime. In addition, our approach offers accurate data recovery from small amounts of compressed data. Simulation results show that our approach can effectively extend the network lifetime of a large‐scale wireless sensor network.     

“How do you know that I don’t understand?” A look at the future of intelligent tutoring systems

Many software systems would significantly improve performance if they could adapt to the emotional state of the user, for example if Intelligent Tutoring Systems (ITSs), ATM’s, ticketing machines could recognise when users were confused, frustrated or angry they could guide the user back to remedial help systems so improving the service. Many researchers now feel strongly that ITSs would be significantly enhanced if computers could adapt to the emotions of students. This idea has spawned the developing field of affective tutoring systems (ATSs): ATSs are ITSs that are able to adapt to the affective state of students. The term “affective tutoring system” can be traced back as far as Rosalind Picard’s book Affective Computing in 1997.This paper presents research leading to the development of Easy with Eve, an ATS for primary school mathematics. The system utilises a network of computer systems, mainly embedded devices to detect student emotion and other significant bio-signals. It will then adapt to students and displays emotion via a lifelike agent called Eve. Eve’s tutoring adaptations are guided by a case-based method for adapting to student states; this method uses data that was generated by an observational study of human tutors. This paper presents the observational study, the case-based method, the ATS itself and its implementation on a distributed computer systems for real-time performance, and finally the implications of the findings for Human Computer Interaction in general and e-learning in particular. Web-based applications of the technology developed in this research are discussed throughout the paper.     

Learning science via animated movies: Its effect on students’ thinking and motivation

Some researchers claim that animations may hinder students’ meaningful learning or evoke misunderstandings. In order to examine these assertions, our study investigated the effect of animated movies on students’ learning outcomes and motivation to learn. Applying the quantitative methodology, two pre- and post-questionnaires were administered: Science thinking skills and Motivation to learn science. Students’ overall achievement in science was examined by their report card scores. The research population (N = 1335) was divided into experimental (N = 926) and control (N = 409) groups from 11 elementary schools. Findings indicated that the use of animated movies promoted students’ explanation ability and their understanding of scientific concepts. Findings also indicated that students who studied science with the use of animated movies developed higher motivation to learn science, in terms of: self-efficacy, interest and enjoyment, connection to daily life, and importance to their future, compared to the control students. Following the definition of multimedia, the students who study with the use of animated movies, applied all three learning styles: visual, auditory and kinesthetic. The use of multimedia and the fact that the students were engaged in exploring new concepts, that were relevant to their daily life experiences, can explain the positive results.     

Accelerating Boyer–Moore searches on binary texts

The Boyer and Moore (BM) pattern matching algorithm is considered as one of the best, but its performance is reduced on binary data. Yet, searching in binary texts has important applications, such as compressed matching. The paper shows how, by means of some pre-computed tables, one may implement the BM algorithm also for the binary case without referring to bits, and processing only entire blocks such as bytes or words, thereby significantly reducing the number of comparisons. Empirical comparisons show that the new variant performs better than regular binary BM and even than BDM.     

Adaptive ROC-based ensembles of HMMs applied to anomaly detection

Hidden Markov models (HMMs) have been successfully applied in many intrusion detection applications, including anomaly detection from sequences of operating system calls. In practice, anomaly detection systems (ADSs) based on HMMs typically generate false alarms because they are designed using limited amount of representative training data. Since new data may become available over time, an important feature of an ADS is the ability to accommodate newly acquired data incrementally, after it has originally been trained and deployed for operations. In this paper, a system based on the receiver operating characteristic (ROC) is proposed to efficiently adapt ensembles of HMMs (EoHMMs) in response to new data, according to a learn-and-combine approach. When a new block of training data becomes available, a pool of base HMMs is generated from the data using a different number of HMM states and random initializations. The responses from the newly trained HMMs are then combined to those of the previously trained HMMs in ROC space using a novel incremental Boolean combination (incrBC) technique. Finally, specialized algorithms for model management allow to select a diversified EoHMM from the pool, and adapt Boolean fusion functions and thresholds for improved performance, while it prunes redundant base HMMs. The proposed system is capable of changing the desired operating point during operations, and this point can be adjusted to changes in prior probabilities and costs of errors. Computer simulations conducted on synthetic and real-world host-based intrusion detection data indicate that the proposed system can achieve a significantly higher level of performance than when parameters of a single best HMM are estimated, at each learning stage, using reference batch and incremental learning techniques. It also outperforms the learn-and-combine approaches using static fusion functions (e.g., majority voting). Over time, the proposed ensemble selection algorithms form compact EoHMMs, while maintaining or improving system accuracy. Pruning allows to limit the pool size from increasing indefinitely, thereby reducing the storage space for accommodating HMMs parameters without negatively affecting the overall EoHMM performance. Although applied for HMM-based ADSs, the proposed approach is general and can be employed for a wide range of classifiers and detection applications.