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排序方式: 共有172条查询结果,搜索用时 15 毫秒
1.
Hossein Karshenas Roberto Santana Concha Bielza Pedro Larrañaga 《Applied Soft Computing》2013,13(5):2412-2432
Regularization is a well-known technique in statistics for model estimation which is used to improve the generalization ability of the estimated model. Some of the regularization methods can also be used for variable selection that is especially useful in high-dimensional problems. This paper studies the use of regularized model learning in estimation of distribution algorithms (EDAs) for continuous optimization based on Gaussian distributions. We introduce two approaches to the regularized model estimation and analyze their effect on the accuracy and computational complexity of model learning in EDAs. We then apply the proposed algorithms to a number of continuous optimization functions and compare their results with other Gaussian distribution-based EDAs. The results show that the optimization performance of the proposed RegEDAs is less affected by the increase in the problem size than other EDAs, and they are able to obtain significantly better optimization values for many of the functions in high-dimensional settings. 相似文献
2.
The main purpose of a gene interaction network is to map the relationships of the genes that are out of sight when a genomic study is tackled. DNA microarrays allow the measure of gene expression of thousands of genes at the same time. These data constitute the numeric seed for the induction of the gene networks. In this paper, we propose a new approach to build gene networks by means of Bayesian classifiers, variable selection and bootstrap resampling. The interactions induced by the Bayesian classifiers are based both on the expression levels and on the phenotype information of the supervised variable. Feature selection and bootstrap resampling add reliability and robustness to the overall process removing the false positive findings. The consensus among all the induced models produces a hierarchy of dependences and, thus, of variables. Biologists can define the depth level of the model hierarchy so the set of interactions and genes involved can vary from a sparse to a dense set. Experimental results show how these networks perform well on classification tasks. The biological validation matches previous biological findings and opens new hypothesis for future studies. 相似文献
3.
Aitor Almeida Pablo Orduña Eduardo Castillejo Diego López-de-Ipiña Marcos Sacristán 《Personal and Ubiquitous Computing》2011,15(4):419-429
As the dependence on mobile devices increases, the need for supporting a wider range of users and devices becomes crucial.
Elders and people with disabilities adopt new technologies reluctantly, a tendency caused by the lack of adaptation of these
technologies to their needs. To address this challenge, this paper describes a framework, Imhotep, whose aim is to aid developers
in the accessible application creation process, making the creation of user-centered applications easier and faster. Our framework
allows to easily adapt the applications to the constraints imposed by the user capabilities (sensorial, cognitive, and physical
capabilities) and device capabilities by providing a repository that will manage the compilation and deployment of applications
that include a set of preprocessor directives in the source code. These directives are enhanced with concepts that are automatically
adjusted to the current trends of mobile devices by using a Fuzzy Knowledge-Eliciting Reasoner. Our final goal is to increase
the number of applications targeted to elders and people with disabilities providing tools that facilitate their development.
The paper also describes the evaluation of both the accuracy of the fuzzy terms generated for mobile devices and the usability
of the proposed platform. 相似文献
4.
Genetic Algorithms for the Travelling Salesman Problem: A Review of Representations and Operators 总被引:8,自引:0,他引:8
P. Larrañaga C.M.H. Kuijpers R.H. Murga I. Inza S. Dizdarevic 《Artificial Intelligence Review》1999,13(2):129-170
This paper is the result of a literature study carried out by the authors. It is a review of the different attempts made to solve the Travelling Salesman Problem with Genetic Algorithms. We present crossover and mutation operators, developed to tackle the Travelling Salesman Problem with Genetic Algorithms with different representations such as: binary representation, path representation, adjacency representation, ordinal representation and matrix representation. Likewise, we show the experimental results obtained with different standard examples using combination of crossover and mutation operators in relation with path representation. 相似文献
5.
6.
Jon Luzuriaga Yurena Polo Oier Pastor-Alonso Beatriz Pardo-Rodríguez Aitor Larraaga Fernando Unda Jose-Ramon Sarasua Jose Ramon Pineda Gaskon Ibarretxe 《International journal of molecular sciences》2021,22(7)
Human dental pulp stem cells (hDPSCs) are some of the most promising stem cell types for regenerative therapies given their ability to grow in the absence of serum and their realistic possibility to be used in autologous grafts. In this review, we describe the particular advantages of hDPSCs for neuroregenerative cell therapies. We thoroughly discuss the knowledge about their embryonic origin and characteristics of their postnatal niche, as well as the current status of cell culture protocols to maximize their multilineage differentiation potential, highlighting some common issues when assessing neuronal differentiation fates of hDPSCs. We also review the recent progress on neuroprotective and immunomodulatory capacity of hDPSCs and their secreted extracellular vesicles, as well as their combination with scaffold materials to improve their functional integration on the injured central nervous system (CNS) and peripheral nervous system (PNS). Finally, we offer some perspectives on the current and possible future applications of hDPSCs in neuroregenerative cell therapies. 相似文献
7.
8.
Aitor Del Coso Umberto Spagnolini Christian Ibars 《Selected Areas in Communications, IEEE Journal on》2007,25(2):402-414
The large number of network nodes and the energy constraints make Wireless Sensor Networks (WSN) one of the most important application fields for Cooperative Diversity. Node cooperation increases the spatial diversity of wireless channels and, thus, reduces the transmitted power. In this paper, we propose a multi-hop WSN with nodes grouped in cooperative clusters that exploits transmit and receive cooperation among cluster nodes. Multi-hop transmission is carried out by concatenating single cluster-to-cluster hops, where every cluster-to-cluster link is defined as a cooperative distributed multiple-input-multiple-output (MIMO) channel. Transmit diversity is exploited through a time-division, decoder-and-forward, relaying scheme based upon two time slots: the Intracluster Slot, used for data sharing within the cluster, and the Intercluster Slot, used for transmission between clusters. At the receiver side, a distributed reception protocol is devised based upon a Selection Diversity algorithm. The proposed multi-hop cooperative WSN is optimally designed for minimum end-to-end outage probability by deriving the optimum time and power allocated on the intracluster and intercluster slots of every single hop, given a per-link energy constraint. A simplified suboptimum resource allocation is also proposed, which performs close to the optimal policy. Results show that the proposed scheme achieves diversity equal to the equivalent MIMO system and significantly reduces energy consumption with respect to. the non-cooperative channel 相似文献
9.
Aitor Mata M. Dolores Mu?oz Emilio Corchado Juan M. Corchado 《Journal of Mathematical Imaging and Vision》2012,42(2-3):212-224
A novel hybrid forecasting Case-Based Reasoning (CBR) system is presented in this interdisciplinary study in which an isotropic buffer operator is applied for case-based creation. Commonly used as an image analysis technique by commercial Geographic Information Systems (GIS), the buffer operator in this particular system calculates the area of an oil slick for prediction and visualization tasks. The use of the buffer operator improves the quality of the data used by the system and in consequence the quality of the results obtained. The system generates predictions by using historical data on oil-slick formation following a spill. 相似文献
10.