全文获取类型
收费全文 | 1202篇 |
免费 | 82篇 |
专业分类
电工技术 | 8篇 |
化学工业 | 531篇 |
金属工艺 | 10篇 |
机械仪表 | 25篇 |
建筑科学 | 30篇 |
能源动力 | 30篇 |
轻工业 | 278篇 |
水利工程 | 9篇 |
石油天然气 | 6篇 |
无线电 | 33篇 |
一般工业技术 | 149篇 |
冶金工业 | 26篇 |
原子能技术 | 3篇 |
自动化技术 | 146篇 |
出版年
2024年 | 4篇 |
2023年 | 22篇 |
2022年 | 126篇 |
2021年 | 135篇 |
2020年 | 54篇 |
2019年 | 42篇 |
2018年 | 40篇 |
2017年 | 50篇 |
2016年 | 38篇 |
2015年 | 29篇 |
2014年 | 55篇 |
2013年 | 65篇 |
2012年 | 78篇 |
2011年 | 98篇 |
2010年 | 62篇 |
2009年 | 79篇 |
2008年 | 62篇 |
2007年 | 52篇 |
2006年 | 39篇 |
2005年 | 25篇 |
2004年 | 26篇 |
2003年 | 20篇 |
2002年 | 23篇 |
2001年 | 7篇 |
2000年 | 8篇 |
1999年 | 10篇 |
1998年 | 4篇 |
1997年 | 4篇 |
1996年 | 3篇 |
1995年 | 2篇 |
1994年 | 3篇 |
1993年 | 2篇 |
1992年 | 3篇 |
1991年 | 1篇 |
1989年 | 1篇 |
1988年 | 2篇 |
1987年 | 1篇 |
1985年 | 1篇 |
1984年 | 2篇 |
1983年 | 2篇 |
1981年 | 1篇 |
1979年 | 1篇 |
1977年 | 1篇 |
1976年 | 1篇 |
排序方式: 共有1284条查询结果,搜索用时 15 毫秒
1.
2.
Ilaria Fraudentali Renato A. Rodrigues-Pousada Riccardo Angelini Sandip A. Ghuge Alessandra Cona 《International journal of molecular sciences》2021,22(10)
Polyamines are ubiquitous, low-molecular-weight aliphatic compounds, present in living organisms and essential for cell growth and differentiation. Copper amine oxidases (CuAOs) oxidize polyamines to aminoaldehydes releasing ammonium and hydrogen peroxide, which participates in the complex network of reactive oxygen species acting as signaling molecules involved in responses to biotic and abiotic stresses. CuAOs have been identified and characterized in different plant species, but the most extensive study on a CuAO gene family has been carried out in Arabidopsis thaliana. Growing attention has been devoted in the last years to the investigation of the CuAO expression pattern during development and in response to an array of stress and stress-related hormones, events in which recent studies have highlighted CuAOs to play a key role by modulation of a multilevel phenotypic plasticity expression. In this review, the attention will be focused on the involvement of different AtCuAOs in the IAA/JA/ABA signal transduction pathways which mediate stress-induced phenotypic plasticity events. 相似文献
3.
4.
In this work, a new method for the creation of classifier ensembles is introduced. The patterns are partitioned into clusters to group together similar patterns, a training set is built using the patterns that belong to a cluster. Each of the new sets is used to train a classifier. We show that the approach here presented, called FuzzyBagging, obtains performance better than Bagging. 相似文献
5.
Alessandra Lumini 《Pattern recognition》2006,39(3):495-497
The problem addressed in this paper is the template selection and update in biometrics based on clustering. Template selection is a reliable method to reduce the number of templates used in a biometric system to account for variations observed in a person's biometric data. An efficient method based on clustering with automatic selection of the number of clusters is proposed in this work for finding subgroups of similar templates which are used for prototype selection.Experimental results confirm the advantage of the new method and the importance of adopting a procedure to perform template selection. 相似文献
6.
Luccas M. Barata Eloísa H. Andrade Alessandra R. Ramos Oriel F. de Lemos William N. Setzer Kendall G. Byler Jos Guilherme S. Maia Joyce Kelly R. da Silva 《International journal of molecular sciences》2021,22(2)
This study evaluated the chemical compositions of the leaves and fruits of eight black pepper cultivars cultivated in Pará State (Amazon, Brazil). Hydrodistillation and gas chromatography–mass spectrometry were employed to extract and analyze the volatile compounds, respectively. Sesquiterpene hydrocarbons were predominant (58.5–90.9%) in the cultivars “Cingapura”, “Equador”, “Guajarina”, “Iaçará”, and “Kottanadan”, and “Bragantina”, “Clonada”, and “Uthirankota” displayed oxygenated sesquiterpenoids (50.6–75.0%). The multivariate statistical analysis applied using volatile composition grouped the samples into four groups: γ-Elemene, curzerene, and δ-elemene (“Equador”/“Guajarina”, I); δ-elemene (“Iaçará”/“Kottanadan”/“Cingapura”, II); elemol (“Clonada”/“Uthirankota”, III) and α-muurolol, bicyclogermacrene, and cubebol (“Bragantina”, IV). The major compounds in all fruit samples were monoterpene hydrocarbons such as α-pinene, β-pinene, and limonene. Among the cultivar leaves, phenolics content (44.75–140.53 mg GAE·g−1 FW), the enzymatic activity of phenylalanine-ammonia lyase (20.19–57.22 µU·mL−1), and carotenoids (0.21–2.31 µg·mL−1) displayed significant variations. Due to black pepper’s susceptibility to Fusarium infection, a molecular docking analysis was carried out on Fusarium protein targets using each cultivar’s volatile components. F. oxysporum endoglucanase was identified as the preferential protein target of the compounds. These results can be used to identify chemical markers related to the susceptibility degree of black pepper cultivars to plant diseases prevalent in Pará State. 相似文献
7.
Neuroprotective Effects of Testosterone in the Hypothalamus of an Animal Model of Metabolic Syndrome
Erica Sarchielli Paolo Comeglio Sandra Filippi Ilaria Cellai Giulia Guarnieri Alessandra Marzoppi Sarah Cipriani Linda Vignozzi Annamaria Morelli Mario Maggi 《International journal of molecular sciences》2021,22(4)
Metabolic syndrome (MetS) is known to be associated to inflammation and alteration in the hypothalamus, a brain region implicated in the control of several physiological functions, including energy homeostasis and reproduction. Previous studies demonstrated the beneficial effects of testosterone treatment (TTh) in counteracting some MetS symptoms in both animal models and clinical studies. This study investigated the effect of TTh (30 mg/kg/week for 12 weeks) on the hypothalamus in a high-fat diet (HFD)-induced animal model of MetS, utilizing quantitative RT-PCR and immunohistochemical analyses. The animal model recapitulates the human MetS features, including low testosterone/gonadotropin plasma levels. TTh significantly improved MetS-induced hypertension, visceral adipose tissue accumulation, and glucose homeostasis derangements. Within hypothalamus, TTh significantly counteracted HFD-induced inflammation, as detected in terms of expression of inflammatory markers and microglial activation. Moreover, TTh remarkably reverted the HFD-associated alterations in the expression of important regulators of energy status and reproduction, such as the melanocortin and the GnRH-controlling network. Our results suggest that TTh may exert neuroprotective effects on the HFD-related hypothalamic alterations, with positive outcomes on the circuits implicated in the control of energy metabolism and reproductive tasks, thus supporting a possible role of TTh in the clinical management of MetS. 相似文献
8.
Francesca Piccotti Ilona Rybinska Elisabetta Scoccia Carlo Morasso Alessandra Ricciardi Lorena Signati Tiziana Triulzi Fabio Corsi Marta Truffi 《International journal of molecular sciences》2021,22(7)
Lipofilling (LF) is a largely employed technique in reconstructive and esthetic breast surgery. Over the years, it has demonstrated to be extremely useful for treatment of soft tissue defects after demolitive or conservative breast cancer surgery and different procedures have been developed to improve the survival of transplanted fat graft. The regenerative potential of LF is attributed to the multipotent stem cells found in large quantity in adipose tissue. However, a growing body of pre-clinical evidence shows that adipocytes and adipose-derived stromal cells may have pro-tumorigenic potential. Despite no clear indication from clinical studies has demonstrated an increased risk of cancer recurrence upon LF, these observations challenge the oncologic safety of the procedure. This review aims to provide an updated overview of both the clinical and the pre-clinical indications to the suitability and safety of LF in breast oncological surgery. Cellular and molecular players in the crosstalk between adipose tissue and cancer are described, and heterogeneous contradictory results are discussed, highlighting that important issues still remain to be solved to get a clear understanding of LF safety in breast cancer patients. 相似文献
9.
Alessandra Capanna 《Nexus Network Journal》2016,18(2):567-572
In Melodie di pietre, Adriana Rossi has produced an in-depth analysis of the cloister of San Cugat on the basis of musical notions and symbolism. This provides us with an occasion for some brief reflections on the historic relationships between music and architecture. 相似文献
10.
Laganà K Moretti M Dubini G Raimondi MT 《Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine》2008,222(5):705-715
Mechanical stimuli have been shown to enhance chondrogenesis on both animal and human chondrocytes cultured in vitro. Different mechanical stimuli act simultaneously in vivo in cartilage tissue and their effects have been extensively studied in vitro, although often in a separated manner. A new bioreactor is described where different mechanical stimuli, i.e. shear stress and hydrostatic pressure, can be combined in different ways to study the mechanobiology of tissue engineered cartilage. Shear stress is imposed on cells by forcing the culture medium through the scaffolds, whereas a high hydrostatic pressure up to 15 MPa is generated by pressurizing the culture medium. Fluid-dynamic experimental tests have been performed and successful validation of the bioreactor has been carried out by dynamic culture of tissue-engineered cartilage constructs. The bioreactor system allows the investigation of the combined effects of different mechanical stimuli on the development of engineered cartilage, as well as other possible three-dimensional tissue-engineered constructs. 相似文献