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Listeria monocytogenes continues to pose a food safety risk in ready-to-eat foods, including fresh and soft/semisoft cheeses. Despite L. monocytogenes being detected regularly along the cheese production continuum, variations in cheese style and intrinsic/extrinsic factors throughout the production process (e.g., pH, water activity, and temperature) affect the potential for L. monocytogenes survival and growth. As novel preservation strategies against the growth of L. monocytogenes in susceptible cheeses, researchers have investigated the use of various biocontrol strategies, including bacteriocins and bacteriocin-producing cultures, bacteriophages, and competition with native microbiota. Bacteriocins produced by lactic acid bacteria (LAB) are of particular interest to the dairy industry since they are often effective against Gram-positive organisms such as L. monocytogenes, and because many LAB are granted Generally Regarded as Safe (GRAS) status by global food safety authorities. Similarly, bacteriophages are also considered a safe form of biocontrol since they have high specificity for their target bacterium. Both bacteriocins and bacteriophages have shown success in reducing L. monocytogenes populations in cheeses in the short term, but regrowth of surviving cells can commonly occur in the finished cheeses. Competition with native microbiota, not mediated by bacteriocin production, has also shown potential to inhibit the growth of L. monocytogenes in cheeses, but the mechanisms are still unclear. Here, we have reviewed the current knowledge on the growth of L. monocytogenes in fresh and surface-ripened soft and semisoft cheeses, as well as the various methods used for biocontrol of this common foodborne pathogen.  相似文献   
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This article presents a novel systematic approach to the fabrication of highly functionalized, silica (SiO2) nanoparticles used for the adsorption of heavy‐metal ions (Hg2+, Pb2+, Cd2+, Zn2+). Almost monodispersed silica (SiO2) nanoparticles with narrow particle size distributions of around 85 ± 5 nm were formed using the Stöber process. The prepared SiO2 nanoparticles were successfully surface‐treated during a one‐step procedure by the covalent attachment of mercaptopropyl groups onto the surfaces of the SiO2 nanoparticles. A FTIR spectra analysis confirmed that the binding of the mercaptosilane molecules onto the surface of the silica nanoparticles mediated the Si–O–Si and –SH vibrations. TEM/EDXS micrographs indicated the almost monodispersed and spherical morphology of the prepared product with strong signals of Si and S, thus implying that the coating procedure involving the mercapto groups onto the silica surface had been successfully accomplished. The final results for the heavy‐metal (Hg2+, Pb2+, Cd2+, Zn2+) adsorption showed the strongest affinity within the following sequence Hg2+ (99.9%) > Pb2+ (55.9%) > Cd2+ (50.2%) > Zn2+ (4%). Adsorption equilibrium was achieved after 1 h for all the analyzed samples.  相似文献   
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微处理器运行速度越来越快,在单块芯片中集成的功能也更多.这样做的代价是此类芯片需要消耗更多的能量,这也意味着随着技术进步和时钟速度的提升,处理器变得越来越热.因此系统设计人员被迫更多地关注系统热管理问题,而在小尺寸封装情况下特别具有挑战性.未来一代针对桌面和其它应用的处理器需要消耗100瓦甚至更高的功率.冷却这些部件对于芯片可靠性非常关键,而且对于整个系统也有影响,因为许多处理器在温度太高时都会自动降低工作速度,有些甚至干脆停止工作.  相似文献   
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