Effect of Strain Rate on Discontinuous Flow and Mechanical Characteristics of High-Nitrogenous Steel

Experimental study on the effect of strain rate on discontinuous flow and mechanical characteristics of the high-nitrogenous steel Kh23AG19F has been performed. Within the range of strain rates from 4.62 · 10^-5 to 1.85 · 10 ^-4 s^-1, discontinuous flow, reflected by serration on the tensile diagram, is chiefly determined by intergranular deformation mechanisms. Under strain rates over 1.85 · 10^-2 s^-1, combined deformation modes prevail, which cause a change in the character of discontinuous flow and transform a serrated tensile diagram into a wavy graph, with the yield stress of steel increased significantly.     

DNA methylation and developmental genes in lymphomagenesis--more questions than answers?

There is now considerable evidence suggesting that alterations in the DNA methylating machinery play an important role in tumorigenesis and tumour progression. For example, focal hypermethylation and generalised genomic demethylation are features of many different types of neoplasms. It is thought that tumorigenesis and tumour progression may be caused by hypermethylation induced mutational events and silencing of genes which control cellular proliferation and/or demethylation induced reactivation of genes which may only be required during embryological development. Consequently, we have begun to investigate the role of DNA methylation and developmental genes in malignant lymphoproliferative diseases. Previously, in all cases of non-Hodgkins lymphoma and leukemia studied, we have shown that the myogenic developmental gene Myf-3 is abnormally hypermethylated. In this review we discuss the possible significance of these findings since in vitro studies suggest that Myf-3 may play an important role in control of the cell cycle and therefore lymphomagenesis. In vitro and in vivo evidence suggests that PAX genes may also have oncogenic potential. The PAX family of developmental genes are involved in cellular differentiation, proliferation and cell migration. Expression of PAX3 in particular is associated with cellular mobility. Our previous studies have indicated that alternate regional expression of PAX genes may be controlled by DNA methylation. Therefore, we have proposed that abnormal methylation profiles of PAX3 may be associated with neoplastic transformation and/or metastatic potential. Results thus far reveal that the paired box of PAX3 is abnormally hypermethylated and the homeobox abnormally hypomethylated in lymphomas and leukemias. These new findings are consistent with our postulate and support the idea that inappropriate methylation induced activation or inactivation of developmental genes such as Myf-3 and PAX3 play an important role in lymphomagenesis and disease progression and that inspection of the methylation status of other developmental genes is warranted.     

Change in the structure and mechanical properties of complex glass fibres during dyring

Stekloplastik—Sertifikat Corporation Moscow. Translated from Khimicheskie Volokna, No. 2, pp. 58–59, March–April, 1994.     

Statistics of mesoplasma channel formation upon thermal breakdown stabilization in thin semiconductor films

A phenomenological model of the development of thermal breakdown in semiconductor films is considered, and it is shown that the average number of mesoplasma channels experimentally observed in the regime of thermal breakdown stabilization can substantially vary. The probability distribution function for the number of such luminous channels arising as a result of thermal fluctuations in a thin semiconductor film is calculated within the framework of a simple approximation.     

Formation of sediment in used industrial oil. Effect of temperature and solvent

Precipitation of sediment caused by external factors — temperature and solvent — is due to the spin nature of the contaminants formed during use of the oil. These paramagnetic contaminants also lead to aging of oils. Their total elimination restores the properties of used oil to the level of the base oil, but requires sufficient energy effects. __________ Translated from Khimiya i Tekhnologiya Topliv i Masel, No. 1, pp. 29–31, January–February, 2006.