全文获取类型
收费全文 | 2365篇 |
免费 | 139篇 |
国内免费 | 3篇 |
专业分类
电工技术 | 13篇 |
综合类 | 4篇 |
化学工业 | 643篇 |
金属工艺 | 26篇 |
机械仪表 | 43篇 |
建筑科学 | 102篇 |
矿业工程 | 2篇 |
能源动力 | 59篇 |
轻工业 | 412篇 |
水利工程 | 26篇 |
石油天然气 | 5篇 |
无线电 | 102篇 |
一般工业技术 | 404篇 |
冶金工业 | 395篇 |
原子能技术 | 5篇 |
自动化技术 | 266篇 |
出版年
2023年 | 16篇 |
2022年 | 92篇 |
2021年 | 166篇 |
2020年 | 64篇 |
2019年 | 63篇 |
2018年 | 82篇 |
2017年 | 63篇 |
2016年 | 67篇 |
2015年 | 54篇 |
2014年 | 78篇 |
2013年 | 147篇 |
2012年 | 142篇 |
2011年 | 167篇 |
2010年 | 122篇 |
2009年 | 124篇 |
2008年 | 122篇 |
2007年 | 115篇 |
2006年 | 103篇 |
2005年 | 78篇 |
2004年 | 66篇 |
2003年 | 56篇 |
2002年 | 50篇 |
2001年 | 32篇 |
2000年 | 25篇 |
1999年 | 28篇 |
1998年 | 61篇 |
1997年 | 47篇 |
1996年 | 32篇 |
1995年 | 22篇 |
1994年 | 23篇 |
1993年 | 22篇 |
1992年 | 10篇 |
1991年 | 9篇 |
1990年 | 14篇 |
1989年 | 15篇 |
1988年 | 10篇 |
1987年 | 18篇 |
1986年 | 10篇 |
1985年 | 13篇 |
1984年 | 4篇 |
1983年 | 10篇 |
1982年 | 8篇 |
1981年 | 6篇 |
1980年 | 10篇 |
1977年 | 4篇 |
1976年 | 9篇 |
1975年 | 6篇 |
1973年 | 3篇 |
1972年 | 3篇 |
1971年 | 3篇 |
排序方式: 共有2507条查询结果,搜索用时 15 毫秒
1.
Abulyazied Dalia E. Alturki Asma M. Youness Rasha A. Abomostafa H. M. 《Journal of Inorganic and Organometallic Polymers and Materials》2021,31(10):4077-4092
Journal of Inorganic and Organometallic Polymers and Materials - In this work, a borosilicate glass sample (5SiO2–45B2O3–20Na2O–25CaO–5Ag2O) was added to nano-sized... 相似文献
2.
Elisa Mascolo Francesco Liguori Lorenzo Stufera Mecarelli Noemi Amoroso Chiara Merigliano Susanna Amadio Cinzia Volont Roberto Contestabile Angela Tramonti Fiammetta Vernì 《International journal of molecular sciences》2021,22(2)
Maturity-onset diabetes of the young (MODY) type 2 is caused by heterozygous inactivating mutations in the gene encoding glucokinase (GCK), a pivotal enzyme for glucose homeostasis. In the pancreas GCK regulates insulin secretion, while in the liver it promotes glucose utilization and storage. We showed that silencing the Drosophila GCK orthologs Hex-A and Hex-C results in a MODY-2-like hyperglycemia. Targeted knock-down revealed that Hex-A is expressed in insulin producing cells (IPCs) whereas Hex-C is specifically expressed in the fat body. We showed that Hex-A is essential for insulin secretion and it is required for Hex-C expression. Reduced levels of either Hex-A or Hex-C resulted in chromosome aberrations (CABs), together with an increased production of advanced glycation end-products (AGEs) and reactive oxygen species (ROS). This result suggests that CABs, in GCK depleted cells, are likely due to hyperglycemia, which produces oxidative stress through AGE metabolism. In agreement with this hypothesis, treating GCK-depleted larvae with the antioxidant vitamin B6 rescued CABs, whereas the treatment with a B6 inhibitor enhanced genomic instability. Although MODY-2 rarely produces complications, our data revealed the possibility that MODY-2 impacts genome integrity. 相似文献
3.
Guglielmina Chimienti Anna Picca Flavio Fracasso Francesco Russo Antonella Orlando Giuseppe Riezzo Christiaan Leeuwenburgh Vito Pesce Angela Maria Serena Lezza 《International journal of molecular sciences》2021,22(4)
Calorie restriction (CR) is the most efficacious treatment to delay the onset of age-related changes such as mitochondrial dysfunction. However, the sensitivity of mitochondrial markers to CR and the age-related boundaries of CR efficacy are not fully elucidated. We used liver samples from ad libitum-fed (AL) rats divided in: 18-month-old (AL-18), 28-month-old (AL-28), and 32-month-old (AL-32) groups, and from CR-treated (CR) 28-month-old (CR-28) and 32-month-old (CR-32) counterparts to assay the effect of CR on several mitochondrial markers. The age-related decreases in citrate synthase activity, in TFAM, MFN2, and DRP1 protein amounts and in the mtDNA content in the AL-28 group were prevented in CR-28 counterparts. Accordingly, CR reduced oxidative mtDNA damage assessed through the incidence of oxidized purines at specific mtDNA regions in CR-28 animals. These findings support the anti-aging effect of CR up to 28 months. Conversely, the protein amounts of LonP1, Cyt c, OGG1, and APE1 and the 4.8 Kb mtDNA deletion content were not affected in CR-28 rats. The absence of significant differences between the AL-32 values and the CR-32 counterparts suggests an age-related boundary of CR efficacy at this age. However, this only partially curtails the CR benefits in counteracting the generalized aging decline and the related mitochondrial involvement. 相似文献
4.
5.
Maria A. Ospina Monica Pizarro Thierry Tran Julien Ricci John Belalcazar Jorge L. Luna Luis F. Londoño Sandra Salazar Hernan Ceballos Dominique Dufour Luis A. Becerra Lopez-Lavalle 《International Journal of Food Science & Technology》2021,56(3):1343-1353
The objective of this study was to characterise the nutritional potential of leaves and identify a diversity centre with low cyanide and high nutrient content among 178 Latin American cassava genotypes. This field-based collection represents the seven diversity centres, held at The International Center for Tropical Agriculture (CIAT Palmira, Colombia) by the Cassava Program. The cyanide, all-trans-β-carotene and lutein concentrations in cassava leaves ranged from 346 to 7484 ppm dry basis (db), from 174–547 μg g−1 db and 15–181 μg g−1 db, respectively. Cassava leaves also showed significant levels of essential amino acids leucine, lysine, phenylalanine, valine and threonine, and average total protein content of 26.24 g 100 g−1 db. Among seven diversity centres, South American rainforest group showed low cyanide and high carotene content in leaves. In addition, VEN77 and PAN51 genotypes stood out for having low cyanide in leaves and roots and high carotene in leaves. This genetic diversity can be used to select high potential progenitors for breeding purposes. 相似文献
6.
Nicolas Guerda; DeSilva Angela M.; Grey Kathleen S.; Gonzalez-Eastep Diana 《Canadian Metallurgical Quarterly》2006,37(6):702
Currently, ethnic and racial minority individuals represent a large proportion of the U.S. population, and researchers expect that they will represent the majority of the population by 2050. This shift in U.S. demographics calls for a greater awareness and integration of cultural issues into the assessment and treatment of ethnically and linguistically diverse clients. This article examines the unique beliefs and manifestations of illnesses among Haitians in connection with the American Psychological Association's (APA, 2002) Multicultural Guidelines. The authors use a common culture-bound syndrome, Séizisman, to illustrate the cultural beliefs, assessment, and treatment of illnesses among Haitians. In so doing, they demonstrate how to incorporate the APA Multicultural Guidelines into treatment with clients of diverse cultural and racial backgrounds. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
7.
Handheld and other battery-powered ICs require process scaling to increase functional integration and reduce active power consumption. Scaling also increases leakage current components to the point where standby power is frequently a limiting design factor. A scheme combining low-leakage thick-gate shadow latches and high-performance transistors is presented that decouples performance from standby power in sub-130-nm technologies. Circuit design and operation, including pulse-clocked latches, use of dynamic circuits, and inclusion of scan is presented. The approach is validated by experimental results on a 90-nm process. 相似文献
8.
The use of neural networks as global approximation tool in crashworthiness problems is here investigated. Neural networks are not only asked to return some meaningful indices of the structural behavior but also to reproduce load-time curves during crash phenomena. To contain the number of examples required for the training process, parallel subsystems of small neural networks are designed. Design points for the training process are obtained by explicit finite element analyses performed by PAMCRASH. The settlement of the points in the design domain is defined using a maximum distance concept. The procedure is applied to different typical absorption structures made of aluminum alloy: riveted tubes, honeycomb structures, longitudinal keel beam and intersection elements of helicopter subfloors. 相似文献
9.
Angela M. Zapata-Anzola Carlos A. Rivera-Rondón Jhon Ch. Donato-Rondón 《Lakes & Reservoirs: Research and Management》2006,11(1):29-38
Guatavita Lake is a small, sheltered tropical high mountain lake located in the Colombian Andes, with a closed watershed and a maximum depth of 25 m. It is the freshwater source for human consumption in nearby small towns, as well as being a site of cultural value for the country, as it was a sacred place to indigenous peoples until about five centuries ago. As the structure and function of this aquatic ecosystem is poorly understood, this study provides initial knowledge on its phytoplankton biomass dynamics, which should be useful in designing efficient management plans with environmental baseline information for similar lakes elsewhere. Physical and chemical data, and photosynthetic pigment concentrations, were measured for the period November 1999–November 2000 at the central vertical axis of Guatavita Lake. The vertical profile of the chlorophyll‐a concentration was closely related to the dissolved inorganic nitrogen concentrations and the thermal stratification characteristics. The maximum chlorophyll‐a concentration in the metalimnion was recorded for the thermal stratification period (November 1999–June 2000). Deepening of the maximum chlorophyll‐a concentration began in February, continuing to June, when it reached its lowest value at the 15 m depth. The phytoplankton biomass values showed an increment within the entire water column at the beginning of the mixing period (July). The relation between the metalimnetic peak of chlorophyll‐a and the dissolved inorganic nitrogen concentration suggests the growth of the phytoplankton community is limited mainly by the availability of nitrogen. 相似文献
10.