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1.
H Rosling 《Canadian Metallurgical Quarterly》1993,90(46):4069-4075
Health conditions have improved worldwide; therefore, the division into developed and developing countries no longer holds true. International organizations tend to divide countries into three groups. An increasing number of people are born in middle income countries where health conditions continue to improve. However, in a number of the least developed countries, mortality is on the rise in a spiral of economic stagnation, environmental problems, social misery, and ethnic/civil conflicts. This requires the medical assistance of international agencies from abroad. Since the 1960s there has been a drastic decline of child mortality in developing countries, especially in Asia. 1 billion people live in countries with child mortality under 20/1000, almost 3 billion live in countries with child mortality ranging 20-100/1000, and over 1 billion live in the least developed countries with child mortality over 100/1000. Unicef divides countries into developed, developing, and least developed countries, while the World Bank groups them as high-, medium-, and low-income countries. Thailand's child mortality is the same as that of Russia, while Cuba has a lower rate than Washington, D.C. On the other hand, Singapore is a developed high-income country with one of the world's healthiest populations. Stagnation and conflicts in the former socialist countries mean that many Asian and Latin American countries have better health status than some parts of Europe. Despite Africa's high mortality, its population growth is the highest in the world: in 20 years its population has doubled. Economic stagnation and the debt burden in many of these countries has resulted in ethnic conflicts and the collapse of social institutions: Somalia, southern Sudan, Rwanda, Liberia, Angola, perhaps Zaire, and Mozambique. The organization Physicians Beyond Borders is an example of extending humanitarian help and combatting social collapse in the least developed countries. 相似文献
2.
Ari Paasio Adam Dawidziuk Kari Halonen Veikko Porra 《Analog Integrated Circuits and Signal Processing》1997,12(1):59-70
The paper presents a Cellular Neural Network implementation based on a high gain sigmoid operation. The required simplifications to the original theory are described that allow the use of high gain. With this design black and white images can be processed. The basic building blocks in a cell are described. A 16×16 cells network has been designed and processed with 1.2 micron CMOS technology. Measurement results which show the operation of the network are presented. 相似文献
3.
Relaxed stability and performance conditions for Takagi-Sugeno fuzzy systems with knowledge on membership function overlap. 总被引:1,自引:0,他引:1
Antonio Sala Carlos Ari?o 《IEEE transactions on systems, man, and cybernetics. Part B, Cybernetics》2007,37(3):727-732
This correspondence presents a relaxation of some earlier linear matrix inequality (LMI) conditions, which allow setting up less conservative stability or performance conditions for Takagi-Sugeno fuzzy models. Unlike the previous literature, this correspondence takes into account the knowledge of the membership functions' shape by considering bounds on them and their cross products (interpreted as an overlap measure), introducing auxiliary LMI variables. Numerical examples illustrate the achieved improvements. 相似文献
4.
Lung surfactant replacement has been tested clinically in recent years. In this study the outcome of 31 premature infants with moderate to severe neonatal respiratory distress syndrome (RDS) treated with surfactant was compared to that of 74 prematures with RDS treated conventionally by positive pressure ventilation and supportive care. The groups were well matched for gestational age, birthweight, sex, and Apgar scores at 1 and 5 min. Surfactant treatment resulted in a significant decrease in mortality--from 36.6% in the untreated group to 12.9% in the surfactant-treated group (P < 0.04). This improvement in survival was seen also in prematures with a birthweight < 1,000 g; in the untreated group mortality was 57.6% compared to 23.5% in the treated group (P < 0.05). The incidence of pneumothorax was lower in the treated group--42% vs. 13% (P < 0.01). Surfactant treatment resulted in a trend of more survivors without bronchopulmonary dysplasia or intraventricular hemorrhage, even though surfactant therapy did not change the incidence of either. 相似文献
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7.
Tiihonen P Kinnunen J Töyräs J Mervaala E Pääkkönen A 《Computer methods and programs in biomedicine》2008,89(1):83-92
Monitoring level of consciousness or depth of sedation is essential in modern intensive care units and emergency rooms. Current methods are based on spontaneous EEG providing only indirect information on the reactivity of the brain. Measurement of auditory event-related potentials (ERPs) has been shown to have additional potential for evaluation of the level of consciousness. Unfortunately, compact and easy-to-use devices are not commercially available. In this study a portable battery-powered device for clinical auditory ERP measurements was designed, constructed and validated. The device consists of a five-channel data logger and a 16-bit stereo audio stimulator. The signals are digitized with a 22-bit sigma-delta analogue-to-digital converter and stored to a PC Card hard disk. Prior to the in vivo application, the device was validated with extensive technical tests. Importantly, the RMS noise amplitude of the EEG channels was found to be less than 1 mivroV and the delivered auditory stimulus intensity corresponded accurately the settings (mean difference 0.2+/-0.5 dB). In addition to technical tests the device was successfully validated in vivo. To summarize, a novel portable instrument for measurement of auditory event-related potentials in intensive care environment is introduced. 相似文献
8.
Hemminki Ari; Hoffren Anna-Marja; Takkinen Kristiina; Vehniainen Markus; Makinen Maija-Liisa; Pettersson Kim; Teleman Olle; Soderlund Hans; Teeri Tuula T. 《Protein engineering, design & selection : PEDS》1995,8(2):185-191
Europium chelates provide a non-radioactive alternative forsensitive labelling of antibodies for diagnostic immunoassays.Lysine residues at antibody surfaces are ready targets for labellingby an isothiocyanate derivative of the europium chelate (Eu3+).Here the labelling efficiency of a recombinant anti-human -fetoprotein(hAFP) Fab fragment has been improved by increasing its lysinecontent by protein engineering. Molecular modelling was usedto identify three light chain constant domain surface arginineresidues, R154, R187 and R210, which were mutated to lysineresidues. The mutations did not influence the affinity of thelysine-enriched Fab fragment and its labelling efficiency wasfound to be 40% higher than that of the wildtype Fab fragmentWith low degree of labelling, the affinities of the two Fabfragments were identical and comparable with that of the originalmonoclonal anti-hAFP IgG. With a higher degree of labellingthe affinities of both Fab fragments decreased more than thatof the intact IgG since more lysine residues are available forlabelling in the additional heavy chain constant domains ofthe larger molecule. Electrostatic adsorption and covalent immobilizationof the Fab fragments were characterized by BIAcoreTM and thelysine-enriched Fab fragment was found to be more efficientlyimmobilized to an activated carboxymethyl surface. 相似文献
9.
During the production and recycling of asphalt concrete, bitumen in contact with inorganic particles is exposed to air at high temperatures. As a result an oxidation of bitumen, also known as aging, occurs. The reaction between bitumen and air at 163 °C was studied insitu with and without the presence of inorganic impurities by means of fourier transform infrared spectroscopy in the attenuated reflectance mode. This oxidation was discovered to be a step-wise reaction facilitated by the oxidation of thiols and creation of peroxides within the system. The rate of reaction was demonstrated to depend on the type of impurity present, of which iron (III) chloride was the strongest catalyst. It was further demonstrated that the oxidation reaction is inhibited by the adsorption of thiol species present in the system on copper particles. Combining copper with the iron (III) chloride-containing system also resulted in the inhibition of signal increase in the sulfoxide region of the spectra. The results of this preliminary research on the bitumen oxidation reaction presented are proposed for further research regarding control of aging of asphalt concrete, especially during the recycling works. 相似文献
10.
Composite Materials Based on Shape‐Memory Ti2NiCu Alloy for Frontier Micro‐ and Nanomechanical Applications 下载免费PDF全文