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1.
The distribution of voltage-dependent calcium channel subunits in the central nervous system may provide information about the function of these channels. The present study examined the distribution of three alpha-1 subunits, alpha 1A, alpha 1B and alpha 1E, in the normal human hippocampal formation and parahippocampal gyrus using the techniques of in situ hybridization and immunocytochemistry. All three subunit mRNAs appeared to be similarly localized, with high levels of expression in the dentate granule and CA pyramidal layer. At the protein level, alpha 1A, alpha 1B and alpha 1E subunits were differentially localized. In general, alpha 1A-immunoreactivity was most intense in cell bodies and dendritic processes, including dentate granule cells, CA3 pyramidal cells and entorhinal cortex pre-alpha and pri-alpha cells. The alpha 1B antibody exhibited relatively weak staining of cell bodies but stronger staining of neuropil, especially in certain regions of high synaptic density such as the polymorphic layer of the dentate gyrus and the stratum lucidum and radiatum of the CA regions. The alpha 1E staining pattern shared features in common with both alpha 1A and alpha 1B, with strong immunoreactivity in dentate granule, CA3 pyramidal and entorhinal cortex pri-alpha cells, as well as staining of the CA3 stratum lucidum. These findings suggest regions in which particular subunits may be involved in synaptic communication. For example, comparison of alpha 1B and alpha 1E staining in the CA3 stratum lucidum with calbindin-immuno-reactivity suggested that these two calcium channels subunits may be localized presynaptically in mossy fibre terminals and therefore may be involved in neurotransmitter release from these terminals.  相似文献   
2.
The wavelet domain association rules method is proposed for efficient texture characterization. The concept of association rules to capture the frequently occurring local intensity variation in textures. The frequency of occurrence of these local patterns within a region is used as texture features. Since texture is basically a multi-scale phenomenon, multi-resolution approaches such as wavelets, are expected to perform efficiently for texture analysis. Thus, this study proposes a new algorithm which uses the wavelet domain association rules for texture classification. Essentially, this work is an extension version of an early work of the Rushing et al. [10], [11], where the generation of intensity domain association rules generation was proposed for efficient texture characterization. The wavelet domain and the intensity domain (gray scale) association rules were generated for performance comparison purposes. As a result, Rushing et al. [10], [11] demonstrated that intensity domain association rules performs much more accurate results than those of the methods which were compared in the Rushing et al. work. Moreover, the performed experimental studies showed the effectiveness of the wavelet domain association rules than the intensity domain association rules for texture classification problem. The overall success rate is about 97%.  相似文献   
3.
Liquid-liquid equilibrium (LLE) data for the ternary system water-ethanol-dimethyl succinate have been determined experimentally at temperatures ranging from 298.15 to 318.15 K at 5 K intervals. Complete phase diagrams were obtained by determining solubility and the tie-line data. Tie-line compositions were correlated by Othmer-Tobias method. The universal quasichemical functional group activity coefficient (UNIFAC) and modifiedUNIFAC methods were used to predict the phase equilibrium in the system using the interaction parameters determined from experimental data between groups CH3, CH2, OH, CH3COO and H20. It is found that UNIFAC and modified UNIFAC group interaction parameters used for LLE could not provide a good prediction. Distribution coefficients and separation f~ctors were evaluated for the immiscibility region.  相似文献   
4.
In this research, the effect of different bicarbonate salts (sodium and ammonium) and their doses (0, 1, 2, and 3 g/100 g raw material) in the coating batter formula use and the sequential use of frying oil (1st, 2nd, 3rd, and 4th) on 5-hydroxymethylfurfural and acrylamide contents in coated fried chicken meat. The addition of sodium bicarbonate was efficient for reducing acrylamide content, but it increased browning and 5-hydroxymethylfurfural content compared to the control. When increasing the doses of sodium and ammonium bicarbonate from 1 to 3 g/100 g of raw material, the acrylamide content of samples did not change significantly, although adding sodium bicarbonate significantly reduced the acrylamide content as a control. These research results showed that using about 1 g/100 g raw material sodium bicarbonate rather than ammonium bicarbonate and as little frying oil as possible use during the production of coated and fried meat results in lower contents of 5-hydroxymethylfurfural and acrylamide.  相似文献   
5.
In this study, two full‐scale upflow anaerobic sludge blanket (UASB) reactors, namely TUASB and CUASB, at the wastewater treatment plants of the Tekirdaǧ Alcohol (Raki) and Canakkale Alcohol (Cognac) distilleries were investigated in terms of performance, acetoclastic methanogenic capacity and microbial composition. The results were compared with a previously studied other UASB reactor (IUASB) at the wastewater treatment plant of the Istanbul Alcohol (Raki) Distillery from which the two reactors (TUASB and CUASB) were seeded. The IUASB reactor performed well achieving COD removal efficiencies of no lower than 85% at organic logding rates (OLRs) in the range of 6–11 kg COD m−3 day−1 between 1996 and 2001. During the last one year of operation, between 2000 and 2001, performance of the CUASB reactor in terms of COD removal efficiency was 70–80% at OLRs in a range of 1–4.5 kg COD m−3 day−1 whereas it was 60–80% at OLRs in a range of 2.5–8.5 kg COD m−3 day−1 in the TUASB reactor. At the end of year 2000, specific methanogenic activity (SMA) tests were carried out to determine potential loading capacity and optimum operating conditions of the IUASB, CUASB and TUASB reactors. The potential methane production (PMP) rates of the CUASB, IUASB and TUASB reactors were measured as 230 cm3 CH4 gVSS−1 day−1, 350 cm3 CH4 gVSS−1 day−1 and 376 cm3 CH4 gVSS−1 day−1 respectively. When the PMP rates were compared with actual methane production (AMP) rates obtained from the three UASB reactors, AMP/PMP ratios were evaluated to be 0.18, 0.12 and 0.13 for CUASB, TUASB and IUASB reactors respectively. This showed that the CUASB, TUASB and IUASB reactors were using only 18%, 12% and 13% of their potential acetoclastic methanogenic capacity respectively. These results can be interpreted that the three UASB reactors were underloaded compared with their potential acetoclastic methanogenic capacities. It was, therefore, recommended that the three UASB reactors should be loaded at higher organic loading rates or sludge withdrawn in order to maintain an AMP/PMP ratio of 0.6–0.7, which can ensure desired reactor performance with safer operation. Results of epifluoresence microscopic examinations showed that the percentage of total autofluorescent methanogens was approximately 30% of the total population in sludges from the TUASB and IUASB reactors whereas it was 20% in sludge from the CUASB reactor. The two UASB reactors treating raki distillery wastewaters contained sludges having a higher percentage of autofluorescent methanogenic population and higher acetoclastic methanogenic activity. Copyright © 2004 Society of Chemical Industry  相似文献   
6.
With the growth of competition between nations in our knowledge-based world economy, excellence programs are becoming a national agenda item in developing as well as developed Asian countries. The main purpose of this paper is to compare the goals, funding policies and selection criteria of excellence programs in China, Japan, Korea and Taiwan and to analyze the academic achievement of their top ranked universities in three areas: research output, internationalization, and excellence, by using data from the Shanghai Jiao Tong, QS, and HEEACT rankings. The effectiveness of Taiwan??s ??Development Plan for World Class Universities and Research Centers of Excellence?? was assessed as a case study in the paper via a survey targeting on 138 top administrators from 11 Taiwan??s universities and 30 reviewers. The study found that more funding nations had, the more outputs and outcomes they would gain, for example China. The Taiwan case demonstrates that world-class universities and research centers are needed in Asian nations despite the concerns for inequality which they raise.  相似文献   
7.
A 450 dm3 pilot‐scale upflow anaerobic sludge blanket (UASB) reactor was used for the treatment of a fermentation‐based pharmaceutical wastewater. The UASB reactor performed well up to an organic loading rate (OLR) of 10.7 kg COD m?3 d?1 at which point 94% COD removal efficiency was achieved. This high treatment efficiency did not continue, however and the UASB reactor was then operated at lower OLRs for the remainder of the study. Specific methanogenic activity (SMA) tests were, therefore, carried out to determine the potential loading capacity of the UASB reactor. For this purpose, the SMA tests were carried out at four different initial acetate concentrations, namely 500 mg dm?3, 1000 mg dm?3, 1500 mg dm?3 and 2000 mg dm?3 so that substrate limitation could not occur. The results showed that the sludge sample taken from the UASB reactor (OLR of 6.1 kg COD m?3 d?1) had a potential acetoclastic methane production (PMP) rate of 72 cm3 CH4 g?1 VSS d?1. When the PMP rate was compared with the actual methane production rate (AMP) of 67 cm3 CH4 g?1 VSS d?1 obtained from the UASB reactor, the AMP/PMP ratio was found to be 0.94 which ensured that the UASB reactor was operated using its maximum potential acetoclastic methanogenic capacity. In order to achieve higher OLRs with desired COD removal efficiencies it was recommended that the UASB reactor should be loaded with suitable OLRs pre‐determined by SMA tests. © 2001 Society of Chemical Industry  相似文献   
8.
Examined the effects of a 12-wk exercise training program on the mood states (assessed via the Profile of Mood States [POMS]) of a 27-yr-old spinal-cord-injured male in a rehabilitation hospital. S was administered the POMS immediately before and after the program and once each week during the program. S demonstrated major mood changes following exercise training, indicating a significant decrease in tension, depression, anger, fatigue, and confusion and a significant increase in vigor. Findings support the hypothesis that vigorous physical exercise can be a useful therapeutic strategy with the disabled. (27 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   
9.
10.
It is contended that rehabilitation psychologists have remained content to continue using the same techniques for the same types of problems that they used more than a decade ago. Because of a temerity of thought, rehabilitation psychologists have not extended their particular research and technological expertise into the more major areas of health care. Examples are presented in which such psychological techniques as conditioning and biofeedback were employed to treat successfully a variety of serious health problems. Rather than leave the major areas of investigation and treatment to others, as has traditionally been the case, rehabilitation psychologists are urged to utilize their skills in studying and treating the major physical problems of their patients. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   
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