全文获取类型
收费全文 | 206篇 |
免费 | 9篇 |
专业分类
电工技术 | 11篇 |
化学工业 | 50篇 |
金属工艺 | 3篇 |
机械仪表 | 4篇 |
建筑科学 | 4篇 |
能源动力 | 4篇 |
轻工业 | 31篇 |
水利工程 | 1篇 |
无线电 | 13篇 |
一般工业技术 | 31篇 |
冶金工业 | 47篇 |
原子能技术 | 3篇 |
自动化技术 | 13篇 |
出版年
2024年 | 1篇 |
2022年 | 4篇 |
2021年 | 11篇 |
2020年 | 4篇 |
2019年 | 1篇 |
2018年 | 4篇 |
2017年 | 6篇 |
2016年 | 4篇 |
2015年 | 6篇 |
2014年 | 9篇 |
2013年 | 10篇 |
2012年 | 17篇 |
2011年 | 10篇 |
2010年 | 13篇 |
2009年 | 9篇 |
2008年 | 8篇 |
2007年 | 6篇 |
2006年 | 9篇 |
2005年 | 3篇 |
2004年 | 1篇 |
2003年 | 4篇 |
2002年 | 1篇 |
2001年 | 1篇 |
2000年 | 3篇 |
1999年 | 9篇 |
1998年 | 19篇 |
1997年 | 6篇 |
1996年 | 8篇 |
1995年 | 6篇 |
1994年 | 8篇 |
1993年 | 1篇 |
1991年 | 2篇 |
1990年 | 3篇 |
1988年 | 1篇 |
1985年 | 2篇 |
1981年 | 3篇 |
1978年 | 1篇 |
1976年 | 1篇 |
排序方式: 共有215条查询结果,搜索用时 15 毫秒
1.
2.
3.
4.
S Kudoh I Komuro Y Hiroi Y Zou K Harada T Sugaya N Takekoshi K Murakami T Kadowaki Y Yazaki 《Canadian Metallurgical Quarterly》1998,273(37):24037-24043
Many lines of evidence have suggested that angiotensin II (AngII) plays an important role in the development of cardiac hypertrophy through AngII type 1 receptor (AT1). To determine whether AngII is indispensable for the development of mechanical stress-induced cardiac hypertrophy, we examined the activity of mitogen-activated protein kinase (MAPK) family and the expression of the c-fos gene as hypertrophic responses after stretching cultured cardiac myocytes of AT1a knockout (KO) mice. When cardiac myocytes were stretched by 20% for 10 min, extracellular signal-regulated protein kinases (ERKs) were strongly activated in KO cardiomyocytes as well as wild type (WT) myocytes. Both basal and stimulated levels of ERKs were higher in cardiomyocytes of KO mice than in those of WT mice. Activation of another member of the MAPK family, p38(MAPK), and expression of the c-fos gene were also induced by stretching cardiac myocytes of both types of mice. An AT1 antagonist attenuated stretch-induced activation of ERKs in WT cardiomyocytes but not in KO cardiomyocytes. Down-regulation of protein kinase C inhibited stretch-induced ERK activation in WT cardiomyocytes, whereas a broad spectrum tyrosine kinase inhibitor (genistein) and selective inhibitors of epidermal growth factor receptor (tyrphostin, AG1478, and B42) suppressed stretch-induced activation of ERKs in KO cardiac myocytes. Epidermal growth factor receptor was phosphorylated at tyrosine residues by stretching cardiac myocytes of KO mice. These results suggest that mechanical stretch could evoke hypertrophic responses in cardiac myocytes that lack the AT1 signaling pathway possibly through tyrosine kinase activation. 相似文献
5.
H. Kawano H. Yoshizawa H. Takeya K. Kadowaki 《Journal of Low Temperature Physics》1996,105(5-6):1635-1640
Recently we have discovered a new peak with phonon character which appears only below Tc in an intermetallic superconductor, YNi2
11B2C (Tc14-2K) by neutron inelastic scattering measurements. The peak intensity of the new peak shows the order-parameter-like temperature dependence of the superconductivity. The new peak grows by absorbing the spectral weight from the above-lying soft phonon mode. In the present study we investigate the magnetic field dependence of the new peak. With increasing magnetic field, the new peak is gradually suppressed and disappears by H=Hc2 (4.7T at T=5.5K). Beyond Hc2, the profile of the scattering function recovers that of the non-superconducting state above Tc These results strongly indicate that this new peak is undoubtedly associated with the superconducting state in YNi2
11B2C. 相似文献
6.
Koji Kamagata Christina Andica Ayumi Kato Yuya Saito Wataru Uchida Taku Hatano Matthew Lukies Takashi Ogawa Haruka Takeshige-Amano Toshiaki Akashi Akifumi Hagiwara Shohei Fujita Shigeki Aoki 《International journal of molecular sciences》2021,22(10)
There has been an increasing prevalence of neurodegenerative diseases with the rapid increase in aging societies worldwide. Biomarkers that can be used to detect pathological changes before the development of severe neuronal loss and consequently facilitate early intervention with disease-modifying therapeutic modalities are therefore urgently needed. Diffusion magnetic resonance imaging (MRI) is a promising tool that can be used to infer microstructural characteristics of the brain, such as microstructural integrity and complexity, as well as axonal density, order, and myelination, through the utilization of water molecules that are diffused within the tissue, with displacement at the micron scale. Diffusion tensor imaging is the most commonly used diffusion MRI technique to assess the pathophysiology of neurodegenerative diseases. However, diffusion tensor imaging has several limitations, and new technologies, including neurite orientation dispersion and density imaging, diffusion kurtosis imaging, and free-water imaging, have been recently developed as approaches to overcome these constraints. This review provides an overview of these technologies and their potential as biomarkers for the early diagnosis and disease progression of major neurodegenerative diseases. 相似文献
7.
8.
Nongluk Sriwilaijaroen Akio Kadowaki Yuriko Onishi Nobuki Gato Makoto Ujike Takato Odagiri Masato Tashiro Yasuo Suzuki 《Food chemistry》2011
Fruit-juice concentrate of Japanese apricot (Prunus mume Sieb. et Zucc.) has been shown to be effective against influenza A infection in MDCK cells. In this study, we isolated five components from the fruit-juice concentrate of Japanese apricot, 5-(hydroxymethyl)-2-formylfuran (HMF), 1-[5-(2-formylfuryl)methyl]dihydrogen 2-hydroxypropane-1,2,3-tricarboxylate (mumefural, MF), 2-[5-(2-formylfuryl)methyl]dihydrogen 2-hydroxypropane-1,2,3-tricarboxylate (MF‘), 1-[5-(2-formylfuryl)methyl]hydrogen 1-hydroxyethane-1,2-dicarboxylate (MA1) and 2-[5-(2-formylfuryl)methyl]hydrogen 1-hydroxyethane-1,2-dicarboxylate (MA2), and investigated their inhibitory activities against the novel influenza A/Narita/1/2009 (H1N1) pandemic virus hemagglutinin and neuraminidase functions, which are essential for viral attachment and budding, respectively. An hemagglutination inhibition assay indicated that MF and MF‘ were effective at minimum hemagglutination concentrations of 3.1 and 6.3 mM, respectively. An inhibition study for sialidase activity of the neuraminidase spike showed that MF was the most active anti-sialidase compound with an IC50 value of 0.21 ± 0.01 mM, followed by MA2 (IC50, 0.71 ± 0.09 mM), MA1 (IC50, 1.64 ± 0.31 mM) and MF‘(IC50, 1.62 ± 0.22 mM). Furthermore, MF was shown to inhibit the growth of the pandemic virus in a dose-dependent manner (62 ± 3% inhibition at 5 mM). The results suggest that MF, a citric acid ester linked to HMF at the 1-position of the propane backbone, might be a lead compound for the development of anti-influenza A inhibitors. 相似文献
9.
J. Mesot M. R. Norman H. Ding M. Randeria J. C. Campuzano A. Paramekanti H. M. Fretwell A. Kaminski T. Takeuchi T. Yokoya T. Sato T. Takahashi T. Mochiku K. Kadowaki 《Journal of Low Temperature Physics》1999,117(3-4):365-369
We use the gradient of the energy-integrated angle resolved photoemission (ARPES) intensity in order to define precisely the Fermi surface (FS) in BSCCO superconductors. We show that, independent of the photon energy, the FS is a hole barrel centered at (, ). Then, the superconducting gap along the FS is precisely determined from ARPES measurements on overdoped and underdoped samples of Bi2212. As the doping decreases, the maximum gap increases, but the slope of the gap near the nodes decreases. Though consistent with d-wave symmetry, the gap with underdoping cannot be fit by the simple cos(k
x) – cos(k
y) form. A comparison of our ARPES results with available penetration depth data indicates that the renormalization of the linear T suppression of the superfluid density at low temperatures due to quasiparticle excitations around the d-wave nodes is large and doping dependent. 相似文献
10.
Distribution and biliary and fecal excretion of bile acids were examined in Wistar strain male rats of about 300 g body weight.
The pool size of the rats on ordinary diet was 40 mg/rat, biliary secretion was 14 mg/hr, and fecal excretion was 10 mg/day.
Bile acids were mainly located in the small and large intestinal contents, 87% and 10%, respectively; but a portion was found
in the intestinal wall and the liver. Rats fed 2% cholesterol-supplemented diet for a week showed similar values for pool
size and biliary secretion with the rats on ordinary diet, but higher values for fecal excretion and distribution ratio in
the large intestinal contents. Cholic acid was a major component in the bile, small intestinal wall, small intestinal content
and liver, while the bile acid composition ratios were roughly similar to each other, although a relatively large amount of
α-muricholic acid was found in the intentinal wall and liver. Both the wall and content compositions of the large intestine
were similar to that of the feces, in which lithocholic, deoxycholic, α- and β-muricholic acids were the main components,
although the ratios of α- and β-muricholic acids in the large intestinal wall were larger than those in the intestinal contents
or feces. The high concentrations of these bile acids may indicate a difference of transport velocity across the cell membrane,
but the mechanism is not known. 相似文献