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排序方式: 共有257条查询结果,搜索用时 31 毫秒
1.
Abhendra K. Singh Kaitlyn Kahle Hannah James Allison L. Horner Daniel Villaflor Zach Benedict 《Ceramics International》2021,47(12):17268-17275
In this study the effects of high temperature and moisture on the impact damage resistance and mechanical strength of Nextel 610/alumina silicate ceramic matrix composites were experimentally evaluated. Composite laminates were exposed to either a 1050°C isothermal furnace-based environment for 30 consecutive days at 6 h a day, or 95% relative humidity environment for 13 consecutive days at 67°C. Low velocity impact, tensile and short beam strength tests were performed on both ambient and environmentally conditioned laminates and damage was characterized using a combination of non-destructive and destructive techniques. High temperature and humidity environmental exposure adversely affected the impact resistance of the composite laminates. For all the environments, planar internal damage area was greater than the back side dent area, which in turn was greater than the impactor side dent area. Evidence of environmental embrittlement through a stiffer tensile response was noted for the high temperature exposed laminates while the short beam strength tests showed greater propensity for interlaminar shear failure in the moisture exposed laminates. Destructive evaluations exposed larger, more pronounced delaminations in the environmentally conditioned laminates in comparison to the ambient ones. External damage metrics of the impactor side dent depth and area directly influenced the post-impact tensile strength of the laminates while no such trend between internal damage area and residual strength could be ascertained. 相似文献
2.
A one-dimensional mesoscopic ring with one input and two output leads acts as a spintronic beam splitter. The spatial degree of freedom, i.e., the presence of two different possible output channels, gets intertwined with the spin direction as a consequence of quantum interference and spin-orbit interaction. We investigate this kind of spatial-spin correlation, and show that the output density operator contains no quantum entanglement in the important special case when the device polarizes a perfectly random input spin state. However, the correlations are in general not purely classical, we also present specific input states with maximal spatial-spin entanglement after the ring. 相似文献
3.
I Beck-Speier N Dayal C Denzlinger C Haberl KL Maier A Ziesenis J Heyder 《Canadian Metallurgical Quarterly》2003,71(3-4):217-234
Recent studies have shown that long-term in vivo exposure of dogs to neutral sulfur(IV)/sulfite aerosols induces mild inflammatory reactions, whereas the combination of neutral sulfite with acidic sulfur(VI)/sulfate aerosols evokes less pronounced effects. To understand underlying mechanisms, we studied in vitro the role of lipid mediators in the responses of alveolar macrophages (AMs) to sulfur-related compounds under neutral (pH 7) or moderate acidic (pH 6) conditions. Canine AMs incubated with sulfite at pH 7 released threefold higher amounts of platelet-activating factor than control (P < 0.005). Generation of arachidonic acid, leukotriene B4, 5-hydroxy-eicosatetraenoic acid, prostaglandin E2, thromboxane B2 and 12-hydroxyheptadecatrienoic acid increased twofold (P < 0.0005). However, these metabolites remained unchanged following incubation of AMs with sulfite at pH 6 or with sulfate at pH 7 or pH 6. Mediator release by sulfite-treated AMs at pH 7 stimulated respiratory burst activity of neutrophils. Inhibition of MAPK pathway by PD 98059, of cytosolic (cPLA2) and secretory phospholipases A2 by AACOCF3 and thioetheramide-PC, respectively, reduced sulfite-induced eicosanoid formation in AMs. Sulfite activated cPLA2 activity twofold at pH 7. This mechanism of sulfite-stimulated responses in phospholipid metabolism predicts that chronic exposure to sulfur(IV)/sulfite is associated with a considerable health risk. 相似文献
4.
Wen-I Li Michael Perzl Joachim Heyder Robert Langer Joseph D. Brain K.-H. Englmeier Ralph W. Niven David A. Edwards 《Journal of aerosol science》1996,27(8):1269-1286
The results of numerical simulations of the aerodynamics and of solid aerosol deaggregation phenomena arising in the process of airflow through various model human oropharyngeal cavities are reported. Special attention is given to the relevance of these simulations to the inhalation of dry-powder therapeutic aerosols. Several two- and three-dimensional mouth and throat geometries (terminating just beyond the larynx) are considered. Cross-sectional area-averaged viscous stress values are numerically determined as a function of distance from the mouth opening. These values, ranging from approximately 10 to 500 dyn cm−2, are compared with estimates of Van der Waals attractive forces per unit area of particle-particle contact so as to evaluate the ability of the flowing airstream to deaggregate aerosol particles that enter the mouth in an aggregated state (held together principally by Van der Waals attractive forces). Estimates of airstream viscous stress differ markedly depending on whether the geometry is two- or three-dimensional. Quantitative differences between flow in a 90°-bend model and an oropharyngeal geometry numerically reconstructed from a cast of a human mouth and throat are especially significant in regards to the ability of the airstream to break apart particle agglomerates. For all geometries it is observed that increasingly smaller particle agglomerates may potentially be separated as the airflow rate increases from 30 to 2001 min−1. At the highest airflows, aggregated particles of diameter near to or even below 1 μm may potentially be separated by the airflow. If separation of particle agglomerates is to occur, it appears far more likely to take place in the throat than in the mouth. This is especially apparent for the more physiologically faithful oropharyngeal geometries considered. 相似文献
5.
Ming Chuang Linjie Luo Benedict J. Brown Szymon Rusinkiewicz Michael Kazhdan 《Computer Graphics Forum》2009,28(5):1475-1484
We present a novel approach for computing and solving the Poisson equation over the surface of a mesh. As in previous approaches, we define the Laplace-Beltrami operator by considering the derivatives of functions defined on the mesh. However, in this work, we explore a choice of functions that is decoupled from the tessellation. Specifically, we use basis functions (second-order tensor-product B-splines) defined over 3D space, and then restrict them to the surface. We show that in addition to being invariant to mesh topology, this definition of the Laplace-Beltrami operator allows a natural multiresolution structure on the function space that is independent of the mesh structure, enabling the use of a simple multigrid implementation for solving the Poisson equation. 相似文献
6.
Summary Carrier sense multiple access (CSMA) protocols were originally conceived for use in digital radio communication. Such protocols are, however, quite applicable in a variety of distributed computing and local networking configurations based on a shared bus. The CSMA protocols are characterized by the fact that message collisions can occur only in a very small time window whose duration corresponds to the propagation delay of the bus. They are further characterized by the technique used to subsequently serialize the transmission of the colliding messages. In this paper we analyze the situation wherein colliding messages are serialized by using a set of staggered retry delays which are associated with the sources that may generate the colliding messages. Our analysis produces both path throughput (utilization) curves and message delay curves, as a function of message generation rate. These curves show that the protocol is in a sense self stabalizing, serve to quantify its behaviour, and indicate loading levels which result in unacceptable message delays. 相似文献
7.
Stankovic A.V. Benedict E.L. John V. Lipo T.A. 《Industry Applications, IEEE Transactions on》2003,39(5):1257-1263
This paper presents a novel method for measuring the magnetizing inductance of an induction machine. The approach uses a static DC excitation technique which can be employed whenever the neutral of the machine is accessible. The proposed method measures only the magnetizing inductance and not the self inductance which normally includes the effect of the stator leakage inductance. Because this test uses a DC excitation, the iron losses in the motor are considerably reduced as well and minimally influence the measurement when compared to the traditional 60-Hz no-load test. By using the proposed method for measuring only the magnetizing inductance, the stator leakage inductance can be later individually determined by performing a separate no-load test. Test results using the method are compared with theoretical values and confirm its feasibility. 相似文献
8.
Hyunjong Byun Jiyeon Park Benedict U. Fabia Joshua Bingwa Mihn Hieu Nguyen Haeshin Lee Jung Hoon Ahn 《International journal of molecular sciences》2022,23(12)
Many heterologous proteins can be secreted by bacterial ATP-binding cassette (ABC) transporters, provided that they are fused with the C-terminal signal sequence, but some proteins are not secretable even though they carry the right signal sequence. The invention of a method to secrete these non-secretable proteins would be valuable both for understanding the secretory physiology of ABC transporters and for industrial applications. Herein, we postulate that cationic “supercharged” regions within the target substrate protein block the secretion by ABC transporters. We also suggest that the secretion of such substrate proteins can be rescued by neutralizing those cationic supercharged regions via structure-preserving point mutageneses. Surface-protruding, non-structural cationic amino acids within the cationic supercharged regions were replaced by anionic or neutral hydrophilic amino acids, reducing the cationic charge density. The examples of rescued secretions we provide include the spike protein of SARS-CoV-2, glutathione-S-transferase, streptavidin, lipase, tyrosinase, cutinase, growth factors, etc. In summary, our study provides a method to predict the secretability and a tool to rescue the secretion by correcting the secretion-blocking regions, making a significant step in understanding the physiological properties of ABC transporter-dependent protein secretion and laying the foundation for the development of a secretion-based protein-producing platform. 相似文献
9.
Thermal analysis of randomly oriented carbon nanotube reinforced functionally graded timoshenko beam
Benedict Thomas Prasad K. Inamdar Tarapada Roy 《Journal of Mechanical Science and Technology》2014,28(5):1779-1788
The unique thermal properties of carbon nanotubes (CNT) are utilized to increase the use of functionally graded material (FGM) at higher temperatures which resulted in introduction of a new type of material called as functionally graded carbon nanotube-reinforced composites (FG-CNTRCs). To use the FG-CNTRCs at elevated temperatures, their thermal analysis is very important. In this context, this article presents the thermal analysis of a CNT based FG Timoshenko beam. Material properties distribution is assumed to vary along the thickness direction according to power law distribution and linear distributions. Finite difference method is implemented to find out the temperature distribution. Using first order shear deformation theory (FSDT), expressions for strains and stresses are obtained. The results are compared with temperature distribution according to power law. The effect of CNT distribution on strains and stresses is also observed. Based on these results important conclusions have been drawn. 相似文献
10.
David Kelly Benedict Ilozor 《International Journal of Construction Education and Research》2019,15(1):3-18
This article reports the findings of a quantitative study on the relationship between various project performance outcomes and the use of Building Information Modeling (BIM), within the commercial construction industry. The literature review identified inconsistent results among prior qualitative and quantitative work concerning the relationships of key project performance measures and BIM use. Data on 13 variables from 93 completed construction projects were collected and examined through a causal comparative research design. Projects that used BIM (in design or construction) were not found to experience significant performance outcomes when controlling for the contribution of other independent variables and covariates at the 95% confidence level (CL). At the lower 90% CL, however, projects using BIM in construction experienced significantly higher levels of schedule growth than projects that did not use BIM in construction. Recommendations are made for training of construction management staff as a step to avoid unwanted schedule growth associated with BIM use during construction. This study is one of a very small group of rigorous quantitative analyses of BIM project performance outcomes conducted to date; additionally, it is the only study that has analyzed BIM in a multivariate context that controlled for the contribution of other project variables not directly related to BIM use. 相似文献