How In-Home Technologies Mediate Caregiving Relationships in Later Life

In-home technologies can support older adults' activities of daily living, provide physical safety and security, and connect elders to family and friends. They facilitate aging in place while reducing caregiver burden. One of older adults' primary concerns about in-home technologies is their potential to reduce human contact, particularly from cherished caregivers. In this exploratory in situ study, we provided an ecosystem of networked monitoring technologies to six older adults and their caregivers. We analyzed the amount and content of communication between them. The amount of noncomputer-mediated communication did not decrease through the 6-week study. The content of communication coalesced into four themes: communication about the technologies, communication facilitated by technologies, intrusiveness of technologies, and fun and playfulness with the technologies. Results suggest that in-home technologies, designed with sensitivity to older adults' primary motivations, have the potential to shape and tailor important relationships in later life.     

Structural Studies of DNA–Cationic Lipid Complexes Confined in Lithographically Patterned Microchannel Arrays

We have used lithographically patterned microchannel arrays with channel widths ranging from 1 to 20 m, fabricated using electron beam lithography and reactive ion etching, in structural studies of DNA–cationic lipid complexes in confinement. Various techniques have been developed for loading these DNA–membrane complexes into the microchannels or to form the complexes in situ by sequentially depositing DNA and lipid solutions into the microchannels. Optical microscopy studies indicate that such complex formation is strongly influenced by the periodic channel structure even at channel widths much larger than the persistent length of the DNA molecules. Preliminary x-ray diffraction experiments conducted at Stanford Synchrotron Radiation Laboratory (SSRL) yielded only a weak signal from the lipid bilayers in the complexes. The use of a microfocused x-ray beam produced by the newly developed Bragg–Fresnel optics at a third-generation synchrotron facility may dramatically increase the signal-to-noise ratio and allow observation of orientational as well as positional ordering of DNA molecules induced by the microchannels. Structural control of the DNA–membrane complexes has a broad range of potential applications in gene probe technology and as mesoscopic biomolecular composites.     

Family planning knowledge, attitudes and practices in women with schizophrenic spectrum disorders

This study set out to test three hypotheses about family planning in women with schizophrenic spectrum disorders, as compared to demographically comparable non-mentally ill control women: that they (1) report at least as much unprotected intercourse while not desiring pregnancy; (2) have less knowledge about contraception; and (3) perceive more, and different, obstacles to obtaining or using birth control. A semistructured Family Planning Interview was administered to subjects (n = 44) with Research Diagnostic Criteria diagnoses of schizophrenia and schizoaffective disorder, and to non-mentally ill control subjects (n = 50). The participants had high rates of unprotected intercourse, as did non-mentally ill controls. They had significantly less reproductive and contraceptive knowledge than the control subjects, and were more likely to perceive birth control as difficult to obtain. The most common reason women with schizophrenic spectrum disorders gave for failing to use birth control was that they did not expect to have sex, while that given by non-mentally ill subjects related to side-effects of birth control. Important obstacles to family planning in women with schizophrenic spectrum disorders include relative lack of knowledge and difficulty planning ahead. Although many women with schizophrenia could benefit from long-acting, reversible contraception, many may be unaware of those options and/or may find them difficult to obtain. Integrating family planning with mental health care might better address the unique needs of this population.     

The influence of outcomes and procedures on satisfaction with formal leaders.

Tested the hypothesis that the procedures used by leaders to allocate outcomes have an impact on leadership evaluations that is independent of outcome level or outcome fairness. Two studies tested this hypothesis within the context of 132 college students' evaluations of teachers, and two tested it within the context of citizen evaluations of political leaders; Ss in the latter 2 studies were 50 residents of a university town and 156 undergraduates. The procedural justice hypothesis was strongly supported by all 4 studies. In each, strong procedural influences on evaluation were found, influences that were independent of outcome level or outcome fairness. In addition, in both surveys of naturally occurring evaluations, variations in procedural fairness had a much greater impact on leadership endorsement than did variations in outcome level, outcome satisfaction, or outcome fairness. Findings suggest that in experimental settings, Ss can be sensitive to both outcomes and procedures. In natural settings, however, individuals focus on procedures rather than outcomes in forming their evaluations of leaders. (20 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The use of off-line part production to predict the tensile properties of parts produced by Selective Laser Sintering

Rapid Manufacturing, and specifically Selective Laser Sintering, has the potential to become one of the most useful manufacturing techniques of the future, largely as a result of the extremely high levels of geometric complexity which can be produced. As the use of these technologies becomes more widespread, so the amount, and variety, of materials available for use in these processes also increases. However, the Selective Laser Sintering process can be both expensive and time-consuming when testing new materials. A method of off-line casting has been proposed here, and the tensile properties of parts produced using this method are compared with the properties achieved in Selective Laser Sintered parts produced in the same materials. For the materials tested it has been shown that the casting method provided an acceptable correlation with the properties of the Selective Laser Sintered parts, rendering this a suitable method of assessing the properties of a Selective Laser Sintering material without the requirement to produce a full build.     

Ceramic fuel cells to replace metal burners

Global warming is thought to result from emissions largely caused by combustion reactions. Designs of burners and specifications of their materials are therefore of primary importance in restraining the warming phenomena. This paper proposes a new type of ceramic burner which incorporates many of the innovations which are needed to improve burner performance, including catalytic combustion, premixed fuel/air, recuperation of combustion heat, recycling of reaction products, electric-ignition and electron extraction. The key problems of fuel variation and thermal shock resistance of the ceramic are addressed through the concept of 'reaction gradient' in which the rich sequence of oxidation reactions during combustion is spread through three extended catalytic regimes along the isothermal ceramic device. It is evident that ceramic burners are necessary to provide catalytic activity and to promote electron transfer. The conclusion is that ceramic will ultimately replace metal in burners requiring low emissions and high exergy output.     

O-GlcNAcylation of key nuclear and cytoskeletal proteins: reciprocity with O-phosphorylation and putative roles in protein multimerization

BACKGROUND: Registered mortality from cryptogenic fibrosing alveolitis (CFA) in England and Wales has increased substantially since the specific International Classification of Diseases code for CFA was introduced in 1979. However, since a significant proportion of deaths from CFA are misclassified as post inflammatory fibrosis (PIF), it is possible that the observed rise in CFA mortality is due to diagnostic transfer from this code. To investigate this, and to assess mortality trends in other countries, annual CFA and PIF mortality data from England and Wales, USA, Australia, Scotland, Canada, New Zealand, and Germany were analysed. METHODS: Crude annual mortality rates were calculated and rates standardised by Poisson regression to allow assessment of changes over time and comparison between countries, sexes, and age groups. The relative trends in mortality from CFA and PIF were assessed by calculating the annual ratio of CFA to PIF deaths. RESULTS: Men were more likely than women to die from both CFA and PIF in all countries. The highest standardised CFA mortality rate occurred in England and Wales, and the lowest in Germany. Since 1979 mortality from CFA has increased in England and Wales, Australia, Scotland and Canada, but there was no trend in CFA mortality in New Zealand or Germany. In the USA mortality from CFA was low and has fallen. Mortality from PIF increased in all countries except New Zealand and Germany, and the highest PIF mortality, together with the greatest increase over time, was seen in the USA. Changes over time in the annual ratio of CFA to PIF deaths in all countries were small, implying that diagnostic transfer is not a major cause of the increasing CFA mortality. CONCLUSIONS: Mortality from CFA continues to increase in England and Wales and in many other countries. Diagnostic transfer from PIF does not appear to be a major cause of this.     

Age differences in behaviors leading to completed suicide

Nonclostridial necrotizing soft-tissue infections are usually polymicrobial, with greater than 90 per cent involving beta-hemolytic streptococci or coagulase-positive staphylococci. The remaining 10 per cent are usually due to Gram-negative enteric pathogens. We describe the case of a 46-year-old woman with bilateral lower extremity fungal soft tissue infections. She underwent multiple surgical debridements of extensive gangrenous necrosis of the skin and subcutaneous fat associated with severe acute arteritis. Histopathological examination revealed Aspergillus niger as the sole initial pathogen. Despite aggressive surgical debridement, allografts, and intravenous amphotericin B, her condition clinically deteriorated and she ultimately died of overwhelming infection. Treatment for soft-tissue infections include surgical debridement and intravenous antibiotics. More specifically, Aspergillus can be treated with intravenous amphotericin B, 5-fluorocytosine, and rifampin. Despite these treatment modalities, necrotizing fascitis is associated with a 60 per cent mortality rate. Primary fungal pathogens should be included in the differential diagnosis of soft-tissue infections.     

Self-control game interventions for attention-deficit hyperactivity disorder.

Compared the effects of self-control training, using cognitive-behavioral game play (CB) and biofeedback game play (BF), on the behaviors of 58 male and 5 female 8–12 yr olds with Full Scale IQ of 90 or higher on the Wechsler Intelligence Scale for Children--Revised (WISC--R) and diagnosed with attention deficit hyperactivity disorder (ADHD). The experimental groups were compared to a control game group (GC), which received no self-control training. A 3?×?3 (treatment?×?time) factorial design with repeated measures, using IQ as a covariate, and multiple outcome criteria was employed comparing the groups. Findings support the hypothesis that self-control training by BF reduces a child's perception of his or her self-control problems, but the same does not generalize to parental report of self-control or behavioral measures. Hyperactivity, one of the cardinal symptoms of ADHD, was significantly decreased in GC. (PsycINFO Database Record (c) 2010 APA, all rights reserved)