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排序方式: 共有169条查询结果,搜索用时 15 毫秒
1.
In this paper, we consider the classical finite mixture model, which is an effective tool for modeling lifetime distributions for random samples from heterogeneous populations. We discuss new results on stochastic comparison for two finite mixtures when each of them is drawn from one of the following semiparametric families, i.e., proportional hazards, accelerated lifetime and proportional reversed hazards. 相似文献
2.
3.
Porous titanium dioxide (Titania) thin films were grown by anodic oxidation using high purity (99.7%) titanium foil in a dilute sulphuric acid (1 M) medium. The anodization process was carried out for 30 minutes with 20 mA/cm2 and 50 mA/cm2 current densities. The samples were characterized by XRD, SEM, and AFM techniques. It was found that the grown porous titania films were less sensitive to 500 ppm hydrogen in air ambient below 300°C; however, the sensitivity and response behavior of the film at 300°C are very much dependent on the growth conditions. Particularly, the films grown at current density 50 mA/cm2 and 1 M acid concentration exhibited the lowest response time of 151 sec at 300°C. 相似文献
4.
Chinmay Vijay Tikhe Victor Cardoso-Jaime Shengzhang Dong Natalie Rutkowski George Dimopoulos 《International journal of molecular sciences》2022,23(14)
Cysteine-rich trypsin inhibitor-like domain (TIL)-harboring proteins are broadly distributed in nature but remain understudied in vector mosquitoes. Here we have explored the biology of a TIL domain-containing protein of the arbovirus vector Aedes aegypti, cysteine-rich venom protein 379 (CRVP379). CRVP379 was previously shown to be essential for dengue virus infection in Ae. aegypti mosquitoes. Gene expression analysis showed CRVP379 to be highly expressed in pupal stages, male testes, and female ovaries. CRVP379 expression is also increased in the ovaries at 48 h post-blood feeding. We used CRISPR-Cas9 genome editing to generate two mutant lines of CRVP379 with mutations inside or outside the TIL domain. Female mosquitoes from both mutant lines showed severe defects in their reproductive capability; mutant females also showed differences in their follicular cell morphology. However, the CRVP379 line with a mutation outside the TIL domain did not affect male reproductive performance, suggesting that some CRVP379 residues may have sexually dimorphic functions. In contrast to previous reports, we did not observe a noticeable difference in dengue virus infection between the wild-type and any of the mutant lines. The importance of CRVP379 in Ae. aegypti reproductive biology makes it an interesting candidate for the development of Ae. aegypti population control methods. 相似文献
5.
Chinmay Rao Asok Ray Soumik Sarkar Murat Yasar 《Signal, Image and Video Processing》2009,3(2):101-114
Symbolic dynamic filtering (SDF) has been recently reported in literature as a pattern recognition tool for early detection
of anomalies (i.e., deviations from the nominal behavior) in complex dynamical systems. This paper presents a review of SDF
and its performance evaluation relative to other classes of pattern recognition tools, such as Bayesian Filters and Artificial
Neural Networks, from the perspectives of: (i) anomaly detection capability, (ii) decision making for failure mitigation and
(iii) computational efficiency. The evaluation is based on analysis of time series data generated from a nonlinear active
electronic system.
This work has been supported in part by the U.S. Army Research Laboratory and the U.S. Army Research Office under Grant No.
W911NF-07-1-0376, by the U.S. Office of Naval Research under Grant No. N00014-08-1-380, and by NASA under Cooperative Agreement
No. NNX07AK49A. 相似文献
6.
Chinmay Mallik Shyam Lal Manish Naja Duli Chand S. Venkataramani Hema Joshi 《International journal of remote sensing》2013,34(8):2749-2762
The combustion of fossil fuels (coal and petroleum products) constitutes a source of continuous release of anthropogenic SO2 into the atmosphere. Furthermore, natural sources such as volcanoes can inject large amounts of SO2 directly into the troposphere and sometimes even into the stratosphere. These event-based volcanic eruptions provide solitary opportunities to study the transport and transformation of atmospheric constituents. In this study, we present an episode of high SO2 concentration over northern India as a result of long-range transport from Africa using multiple satellite observations. Monthly averaged column SO2 values over the Indo-Gangetic Plain (IGP) were observed in the range of 0.6–0.9 Dobson units (DU) during November 2008 using observations from the Ozone Monitoring Instrument (OMI). These concentrations were conspicuously higher than the background concentrations (<0.3 DU) observed during 2005–2010 over this region. The columnar SO2 loadings were highest on 6 November over most of the IGP region and even exceeded 6 DU, a factor of 10–20 higher than background levels in some places. These enhanced SO2 levels were not reciprocated in satellite-derived NO2 or CO columns, indicating transport from a non-anthropogenic SO2 source. As most of the local aerosols over the IGP region occur below 3 km, a well-separated layer at 4–5 km was observed from the Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observations (CALIPSO) satellite. Wind fields and back-trajectory analysis revealed a strong flow originating from the Dalaffilla volcanic eruption in Ethiopia during 4–6 November 2008. Although volcanic SO2 plumes have been extensively studied over many parts of Asia, Europe, and the USA, analysis of such events for the IGP region is being reported for the first time in this study. 相似文献
7.
This paper presents an implementation of a genetic algorithm in the structural design of broken contact doublets according to a prespecified set of Gaussian characteristics and primary aberration targets. The objective of this study is to investigate the effectiveness of the algorithm in finding out global as well as useful local optima and its dependence on some parameters characterizing the genetic operators. Actual glasses are taken as variables. Some illustrative examples are given. 相似文献
8.
Ateek Shah Yashwant Kumar S. Rohan Amrita B. Hazra 《Chembiochem : a European journal of chemical biology》2023,24(11):e202300055
Flavin adenine dinucleotide (FAD) is an essential redox cofactor in cellular metabolism. The organic synthesis of FAD typically involves coupling flavin mononucleotide (FMN) with adenosine monophosphate, however, existing synthesis routes present limitations such as multiple steps, low yields, and/or difficult-to-obtain starting materials. In this study, we report the synthesis of FAD nucleobase analogues with guanine/cytosine/uracil in place of adenine and deoxyadenosine in place of adenosine using chemical and enzymatic approaches with readily available starting materials, achieved in 1–3 steps with moderate yields (10–57 %). We find that the enzymatic route using Methanocaldococcus jannaschii FMN adenylyltransferase (MjFMNAT) is versatile and can produce these FAD analogues in high yields. Further, we demonstrate that Escherichia coli glutathione reductase is capable of binding and using these analogues as cofactors. Finally, we show that FAD nucleobase analogues can be synthesized inside a cell from cellular substrates FMN and nucleoside triphosphates by the heterologous expression of MjFMNAT. This lays the foundation for their use in studying the molecular role of FAD in cellular metabolism and as biorthogonal reagents in biotechnology and synthetic biology. 相似文献
9.
Multiwalled carbon nanotubes were irradiated with ultra-low energy (few eV) nitrogen and hydrogen ions using a microwave discharge. These ultra-low energy plasma-ions remain confined to the nanotube walls, transferring their maximum energy to the carbon atoms, and produce extraordinary structural changes to the carbon nanotube pillars as well as within the carbon nanotubes. Conical shaped emitters and nanotube structures with nano-defects are produced that exhibit remarkable field emission with ultra-low turn-on electric field (∼0.16 V/μm) and a >300-fold increase in the maximum emission current density compared to non-irradiated nanotubes. Doping of nitrogen is also identified due to such irradiation processes. 相似文献
10.
TGA experiments on the catalytic cracking of methane and methane diluted with hydrogen over a 5 wt% Ni/γ‐alumina catalyst at 500°C and 1 and 10 bar are described. Carbon deposition on the catalyst, as expressed in specific weight of carbon, varies with time. Eventually, the deposition stops because of deactivation. The specific weight at this point depends on the hydrogen partial pressure and there is also a weak dependence on the degree of contact between catalyst particles. A model based on assuming carbon deposition proceeds through whisker formation and growth, and deactivation occurs through encapsulation adequately describes the experimental observations up to 20 vol% hydrogen in the feed. 相似文献