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1.
Coralia Cartis Nicholas I.M. Gould Philippe L. Toint 《Optimization methods & software》2013,28(3):451-457
This short note considers and resolves the apparent contradiction between known worst-case complexity results for first- and second-order methods for solving unconstrained smooth nonconvex optimization problems and a recent note by Jarre [On Nesterov's smooth Chebyshev–Rosenbrock function, Optim. Methods Softw. (2011)] implying a very large lower bound on the number of iterations required to reach the solution's neighbourhood for a specific problem with variable dimension. 相似文献
2.
Coralia Cotoraci Alina Ciceu Alciona Sasu Anca Hermenean 《International journal of molecular sciences》2021,22(4)
Anemia, characterized by a decrease of the hemoglobin level in the blood and a reduction in carrying capacity of oxygen, is a major public health problem which affects people of all ages. The methods used to treat anemia are blood transfusion and oral administration of iron-based supplements, but these treatments are associated with a number of side effects, such as nausea, vomiting, constipation, and stomach pain, which limit its long-term use. In addition, oral iron supplements are poorly absorbed in the intestinal tract, due to overexpression of hepcidin, a peptide hormone that plays a central role in iron homeostasis. In this review, we conducted an analysis of the literature on biologically active compounds and plant extracts used in the treatment of various types of anemia. The purpose of this review is to provide up-to-date information on the use of these compounds and plant extracts, in order to explore their therapeutic potential. The advantage of using them is that they are available from natural resources and can be used as main, alternative, or adjuvant therapies in many diseases, such as various types of anemia. 相似文献
3.
Coralia Osorio Nelson Hurtado Corinna Dawid Thomas Hofmann Francisco José Heredia-Mira Alicia Lucía Morales 《Food chemistry》2012
The anthocyanin composition of tamarillo (Solanum betaceum Cav., red variety) and Andes berry (Rubus glaucus Benth.) was determined by HPLC–PDA and HPLC–ESIMS. From the anthocyanin-rich extracts (AREs), pure compounds (1–7) were obtained by MLCCC (multilayer countercurrent chromatography) and further preparative HPLC, and their unequivocal structures were obtained by 1D and 2D NMR analyses. The new anthocyanin delphinidin 3-O-α-l-rhamnopyranosyl-(1 → 6)-β-d-glucopyranoside-3′-O-β-d-glucopyranoside, as well as the known cyanidin-3-O-rutinoside, pelargonidin-3-O-rutinoside, and delphinidin-3-O-rutinoside were identified as constituents of tamarillo fruit. Although the anthocyanin composition of Andes berry had been reported before in the literature, the unequivocal structure elucidation of the major compound, cyanidin-3-O-α-l-rhamnopyranosyl-(1 → 6)-O-β-d-xylopyranosyl-(1 → 2)-β-d-glucopyranoside, was achieved for the first time. 相似文献
4.
Diana Cristina Sinuco Martin Steinhaus Peter Schieberle Coralia Osorio 《European Food Research and Technology》2010,230(6):859-864
Changes in the concentrations of odour-active compounds in two varieties of Colombian guava (Psidium guajava L.) fruits during ripening were followed by application of stable isotopic dilution analyses (SIDA). The data revealed that,
in particular, the concentration of C6-aldehydes, as well as the amount of the sulphur compounds 3-sulphanylhexyl acetate and 3-sulphanyl-1-hexanol, decreased with
ripening, while the concentrations of aliphatic esters and furanones increased during this process. A calculation of odour
activity values indicated that although the C6-aldehydes decreased during ripening, these still made the greatest contribution to the overall aroma at all stages of ripening.
Changes in odour-active compounds in white- and pink-fleshed guavas showed the same behaviour. 相似文献
5.
José Luis Villacrez José G. Carriazo Coralia Osorio 《Food and Bioprocess Technology》2014,7(5):1445-1456
The Andes berry (Rubus glaucus Benth.), a tropical fruit with a high anthocyanin content and pleasant aroma, was selected for spray drying to produce solids that preserve the sensory characteristics (colour, odour and taste) of the fresh fruit. A factorial design (9?×?2) was implemented to evaluate the influence of the encapsulating agent (maltodextrin DE 20, arabic gum, corn starch, yucca starch, Capsul® TA and Hi-CapTM 100, as well as three mixtures of them) and the nozzle diameter (1.0 and 2.0 mm) on the characteristics of solids, anthocyanin content, moisture and water activity. All solids showed water activity values (a w) between 0.199 and 0.422, and particle size ranging from 3 to 15 μm according to microscopy results. The samples exhibiting the highest anthocyanin content were subjected to a discriminative sensory analysis. The Andes berry microencapsulates obtained with Hi-CapTM 100 and maltodextrin DE 20 as wall materials were chosen because of their sensory properties. The release of anthocyanins as well as volatile aroma compounds by water dissolution was confirmed by both liquid and gas chromatography coupled to mass spectrometry (HPLC-MS and GCMS, respectively). The chroma (C*ab) and a* values of the solutions were higher than those of the powders, which indicated a more intense red colour. Thermal analyses (thermogravimetric analyses and differential scanning calorimetry) showed that these two solids were stable up to 100 °C under a nitrogen atmosphere. Remarkably, the anthocyanin content did not change during 180 days at 18 °C and a relative humidity of less than 60 %. However, the shelf life of these products is highly dependent on the humidity during storage because a relative humidity increase causes significant damage to the microcapsule structures and the loss of the encapsulated materials. 相似文献
6.
Lee Eun-Jung Yu Mi-Hee Garcia Coralia V. Jhee Kwang-Hwan Yang Seun-Ah 《Food science and biotechnology》2017,26(2):481-487
Food Science and Biotechnology - Zizania latifolia exhibits anti-inflammatory and anti-allergic effects; however, the mechanisms behind these effects are unknown. Here the ethanol extract of Z.... 相似文献
7.
Madalina Tudose Daniela C. Culita Adina M. Musuc Gabriela Marinescu Simona Somacescu Cornel Munteanu Coralia Bleotu Mariana C. Chifiriuc 《Journal of Inorganic and Organometallic Polymers and Materials》2016,26(5):1043-1052
The paper describes a rapid and simple method for preparing a multifunctional biomaterial based on retinoic acid covalently bound on silica@Ag particles. Monodispersed SiO2 particles were prepared by Stöber method and further used for loading the Ag nanoparticles on their surface. This composite was further functionalized with retinoic acid. Characterization of the hybrid materials was made by UV–Visible spectroscopy, Transmission electron microscopy, Scanning electron microscopy, Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy and Thermal analysis. The biological evaluation of the obtained materials revealed their potential use for multiple biomedical applications, from anti-proliferative agents to novel antimicrobial and antibiofilm strategies. 相似文献
8.
Maria Consiglia Trotta Sami Gharbia Hildegard Herman Bianca Mladin Andrei Hermenean Cornel Balta Coralia Cotoraci Victor Eduard Peteu Carlo Gesualdo Francesco Petrillo Marilena Galdiero Roberto Alfano Mihaela Gherghiceanu Michele DAmico Settimio Rossi Anca Hermenean 《International journal of molecular sciences》2021,22(12)
(1) Background: The pro-resolving lipid mediator Resolvin D1 (RvD1) has already shown protective effects in animal models of diabetic retinopathy. This study aimed to investigate the retinal levels of RvD1 in aged (24 months) and younger (3 months) Balb/c mice, along with the activation of macro- and microglia, apoptosis, and neuroinflammation. (2) Methods: Retinas from male and female mice were used for immunohistochemistry, immunofluorescence, transmission electron microscopy, Western blotting, and enzyme-linked immunosorbent assays. (3) Results: Endogenous retinal levels of RvD1 were reduced in aged mice. While RvD1 levels were similar in younger males and females, they were markedly decreased in aged males but less reduced in aged females. Both aged males and females showed a significant increase in retinal microglia activation compared to younger mice, with a more marked reactivity in aged males than in aged females. The same trend was shown by astrocyte activation, neuroinflammation, apoptosis, and nitrosative stress, in line with the microglia and Müller cell hypertrophy evidenced in aged retinas by electron microscopy. (4) Conclusions: Aged mice had sex-related differences in neuroinflammation and apoptosis and low retinal levels of endogenous RvD1. 相似文献
9.
Aroma compounds in fruit are known to occur in free and glycosidically bound forms. The bound volatile fraction of a low flavour kiwifruit species, Actinidia eriantha, was studied. The fruit have a bland and grassy flavour. Glycosidic precursors were isolated from juice by adsorption onto an Amberlite XAD-2 column. After enzymatic hydrolysis with Rapidase AR2000, the released aglycones were analysed by GC–MS. Alcohols, terpenoids and phenolics were the most numerously represented compound classes. Alcohols, benzenoids and phenolics showed the highest concentrations. Major compounds were 2-phenylethanol, furfuryl alcohol, (Z)-3-hexen-1-ol, coniferyl alcohol, isoamyl alcohol and linolenic acid. Several of the bound compounds found, including linoleic, linolenic and benzoic acids and coniferyl alcohol, are precursors of odorous volatiles. Many compounds detected as bound volatiles have not been previously reported as free volatiles in A. eriantha. The bound volatile composition of A. eriantha also showed differences with those of other kiwifruit species. 相似文献
10.
Ivonne Alejandra González Coralia Osorio Antonio Jesús Meléndez‐Martínez Maria Lourdes González‐Miret Francisco José Heredia 《International Journal of Food Science & Technology》2011,46(4):840-848
The pigment composition of three Colombian guava varieties, Regional roja, Regional blanca, and Palmira ICA‐1, in unripe, turning and full ripe maturity stages was studied. Lycopene was identified as the major carotenoid of Regional roja and Palmira ICA‐1 (18.25 and 28.07 mg kg?1 fruit, respectively in full ripe fruits) although a small amount of lutein was also found in the two varieties. β‐Carotene was only found in Palmira ICA‐1, whilst no detectable levels of carotenoids were found in the white‐fleshed guava (Regional blanca). A good correlation between the total carotenoid content and the colour parameters of guava peel was found, such that the Regional roja and Regional blanca varieties could be discerned by colour coordinates. The most remarkable differences were found when comparing the pulp colour. 相似文献