Shape memory crosslinked polyurethanes containing thermoreversible Diels‐Alder couplings

Crosslinked polyurethanes (PUs) containing irreversible (allophanate) and reversible Diels‐Alder chemical bonds were synthesized using various diisocyanates (methylene diphenyl diisocyanate MDI, 1,6‐hexamethylenediisocyanate HDI) and poly(?‐caprolactone) ((PCL) with different molecular weights (M_n = 10 kg/mol, 25 kg/mol, 50 kg/mol) as diol component. The melting/crystallization of PCL and the reversible DA bonds acted as temperature‐activated switches for shape memory performances, while allophanate network provided the permanent crosslinks for these PUs. The reversible DA bonds were obtained by the reaction of diisocyanate‐ended prepolymers with furfurylamine (FA) followed by the addition of bismaleimide (BMI). The permanent crosslinks between the linear chains containing DA bonds were achieved using additional amounts of diisocyanates (MDI or HDI). The above reaction path was supported by infrared spectroscopic results and swelling experiments. Tensile mechanical and shape memory properties in tension of the PUs were determined and discussed as a function of composition and crosslink densities deduced from swelling and dynamic mechanical analysis. © 2016 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016 , 133, 44145.     

Comparison of Two Analytical Methods for Assessing Antioxidant Capacity of Rapeseed and Olive Oils

The oxygen radical absorbance capacity (ORAC) and the ferric reducing antioxidant power (FRAP) methods were used for the determination of antioxidant capacities (AC) of rapeseed oils at different steps of technological process and olive oils. The mean ORAC and FRAP results obtained for rapeseed oils (1,106–160 and 552–95.6 μmol TE/100 g) were higher than for olive oils (949–123 and 167–32.1 μmol TE/100 g). Although, FRAP values were lower than ORAC values for all studied oils, there is a linear and significant correlation between these two analytical methods (r = 0.9665 and 0.9298, P < 0.0005) for rapeseed and olive oils, respectively). Also, total phenolic compounds in rapeseed oils and olives correlated with antioxidant capacities (correlation coefficient ranged between 0.9470 and 0.8049). The refining process of rapeseed oils decreased the total phenolics content and antioxidant capacities by about 80%.     

Role of the Blood-Brain Barrier in the Formation of Brain Metastases

The majority of brain metastases originate from lung cancer, breast cancer and malignant melanoma. In order to reach the brain, parenchyma metastatic cells have to transmigrate through the endothelial cell layer of brain capillaries, which forms the morphological basis of the blood-brain barrier (BBB). The BBB has a dual role in brain metastasis formation: it forms a tight barrier protecting the central nervous system from entering cancer cells, but it is also actively involved in protecting metastatic cells during extravasation and proliferation in the brain. The mechanisms of interaction of cancer cells and cerebral endothelial cells are largely uncharacterized. Here, we provide a comprehensive review on our current knowledge about the role of junctional and adhesion molecules, soluble factors, proteolytic enzymes and signaling pathways mediating the attachment of tumor cells to brain endothelial cells and the transendothelial migration of metastatic cells. Since brain metastases represent a great therapeutic challenge, it is indispensable to understand the mechanisms of the interaction of tumor cells with the BBB in order to find targets of prevention of brain metastasis formation.     

Paraconsistency and Plausible Argumentation in Generative Grammar: A Case Study

While the analytical philosophy of science regards inconsistent theories as disastrous, Chomsky allows for the temporary tolerance of inconsistency between the hypotheses and the data. However, in linguistics there seem to be several types of inconsistency. The present paper aims at the development of a novel metatheoretical framework which provides tools for the representation and evaluation of inconsistencies in linguistic theories. The metatheoretical model relies on a system of paraconsistent logic and distinguishes between strong and weak inconsistency. Strong inconsistency is destructive in that it leads to logical chaos. In contrast, weak inconsistency may be constructive, because it is capable of accounting for the simultaneous presence of seemingly incompatible structures. However, paraconsistent logic cannot grasp the dynamism of the emergence and resolution of weak inconsistencies. Therefore, the metatheoretical approach is extended to plausible argumentation. The workability of this metatheoretical model is tested with the help of a detailed case study on an analysis of discontinuous constituents in Government-Binding Theory.     

Investigation of chromium content in foodstuffs and nutrition supplements by GFAAS and determination of changing Cr(III) to Cr(VI) during baking and toasting bread

In our work the chromium content of foodstuffs, spices, beverages and nutrition supplements was determined. We set out to determine in what quantity these satisfy the organism’s daily chromium requirement. We wanted to get an answer about to the question if a sportsman wants to plan his diet from the chromium consumption point of view, does he believe that the data given satisfy the necessary essential amount of chromium content. The results obtained were compared to data published by other authors and data can be found in the Internet. These data do not only differ significantly from the results obtained by us, but from each other as well. At present there is no available literature data to us demonstrating whether toxic chromium compounds can occur from the natural Cr(III) content of cereal milling products used when baking and toasting bread, that is why we considered examining it.     

Dreissenid colonization during the initial invasion of the quagga mussel in the largest Central European shallow lake,Lake Balaton,Hungary

The colonization progress of the invasive bivalve dreissenids, the formerly dominant Dreissena polymorpha and the recently (2008) introduced Dreissena rostriformis bugensis was studied between 2009 and 2013 in the largest Central European shallow lake, Lake Balaton, Hungary. The density of dreissenid planktonic veligers, new settlers (post-veligers and early juveniles), and the population structure (density, length frequency, relative abundance) of the two species were monitored on experimentally introduced natural stone substrata, on different time scales. Dreissenids started dynamic settling following a sudden veliger bloom. As substratum saturation progressed, competition between species for places was suggested, which, after two years, led to an increased number of large individuals (> 20 mm) and also recruits of D. r. bugensis. By contrast, the population of D. polymorpha was confined to middle size (11–18 mm) individuals of the first settler generation. On local substrata, where the benthic community was already established, the replacement of D. polymorpha by D. r. bugensis took longer, but it happened in a similar way. The invasion speed of D. r. bugensis in Lake Balaton resembled the speed obtained in other European water bodies where D. r. bugensis, similar to Lake Balaton, was introduced much later than D. polymorpha. However, a longer replacement process was found in North America, where both species invaded new habitats at the same time. This suggests that the speed, and probably the success, of D. r. bugensis invasion depends on new surface availability, and whether the two dreissenid species are introduced together or at different times.     

Influence of moisture content on the contact angle and surface tension measured on birch wood surfaces

European Journal of Wood and Wood Products - Surface tension of solid wood surfaces affects the wettability and thus the adhesion of various adhesives and wood coatings. By measuring the contact...     

Helium Conditioning Increases Cardiac Fibroblast Migration Which Effect Is Not Propagated via Soluble Factors or Extracellular Vesicles

Helium inhalation induces cardioprotection against ischemia/reperfusion injury, the cellular mechanism of which remains not fully elucidated. Extracellular vesicles (EVs) are cell-derived, nano-sized membrane vesicles which play a role in cardioprotective mechanisms, but their function in helium conditioning (HeC) has not been studied so far. We hypothesized that HeC induces fibroblast-mediated cardioprotection via EVs. We isolated neonatal rat cardiac fibroblasts (NRCFs) and exposed them to glucose deprivation and HeC rendered by four cycles of 95% helium + 5% CO₂ for 1 h, followed by 1 h under normoxic condition. After 40 h of HeC, NRCF activation was analyzed with a Western blot (WB) and migration assay. From the cell supernatant, medium extracellular vesicles (mEVs) were isolated with differential centrifugation and analyzed with WB and nanoparticle tracking analysis. The supernatant from HeC-treated NRCFs was transferred to naïve NRCFs or immortalized human umbilical vein endothelial cells (HUVEC-TERT2), and a migration and angiogenesis assay was performed. We found that HeC accelerated the migration of NRCFs and did not increase the expression of fibroblast activation markers. HeC tended to decrease mEV secretion of NRCFs, but the supernatant of HeC or the control NRCFs did not accelerate the migration of naïve NRCFs or affect the angiogenic potential of HUVEC-TERT2. In conclusion, HeC may contribute to cardioprotection by increasing fibroblast migration but not by releasing protective mEVs or soluble factors from cardiac fibroblasts.     

Deoxynivalenol in wheat,maize, wheat flour and pasta: surveys in Hungary in 2008–2015

Among Fusarium mycotoxins, deoxynivalenol (DON) is the most common contaminant in case of cereals and cereal-based foods in Hungary. In this study, Hungarian wheat (n = 305), maize (n = 108), wheat flour (n = 179) and pasta (n = 226) samples were analysed (N = 818). The samples were collected during 2008–2015 in Hungary. Applied methods of analysis were enzyme-linked immunosorbent assay and liquid-chromatography coupled with a mass spectrometer. Results were compared and evaluated with Hungarian weather data. Among cereal samples, in 2011, wheat was contaminated with DON (overall average ± standard deviation was 2159 ± 2818 µg kg^?1), which was above the maximum limit (ML). In case of wheat flour and pasta, no average values above ML were found during 2008–2015, but higher DON contamination could be observed in 2011 as well (wheat flour: 537 ± 573 µg kg^?1; pasta: 511 ± 175 µg kg^?1).