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Inherited cardiomyopathies are frequent causes of sudden cardiac death (SCD), especially in young patients. Despite at the autopsy they usually have distinctive microscopic and/or macroscopic diagnostic features, their phenotypes may be mild or ambiguous, possibly leading to misdiagnoses or missed diagnoses. In this review, the main differential diagnoses of hypertrophic cardiomyopathy (e.g., athlete’s heart, idiopathic left ventricular hypertrophy), arrhythmogenic cardiomyopathy (e.g., adipositas cordis, myocarditis) and dilated cardiomyopathy (e.g., acquired forms of dilated cardiomyopathy, left ventricular noncompaction) are discussed. Moreover, the diagnostic issues in SCD victims affected by phenotype-negative hypertrophic cardiomyopathy and the relationship between myocardial bridging and hypertrophic cardiomyopathy are analyzed. Finally, the applications/limits of virtopsy and post-mortem genetic testing in this field are discussed, with particular attention to the issues related to the assessment of the significance of the genetic variants.  相似文献   
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首先以 HERMLE C1200 U 为例分析了五轴铣削加工中心的基本结构,然后据此给出了涉及多轴铣削加工中心后置处理角度分配和坐标变换的数学模型,最后介绍了以此数学模型为核心,为UG 软件开发的后置处理软件 UG-HERP1.0的解决方案。  相似文献   
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Human papillomavirus (HPV) types 16 and 18 in 66 women with histologically documented lesions of the genital tract and 64 control cohorts were investigated. The efficacies of in situ hybridization and polymerase chain reaction (PCR) in detecting HPV 16 and 18 DNA were analyzed. In order to assess the usefulness of replacing biopsies with cervical scrapes, the two samples were compared by PCR. The prevalence rates of HPV infection by PCR were 59.1 and 10.9% in patients and controls, respectively. PCR was three times more sensitive than in situ hybridization (52.6 versus 17.8%). However, the need to improve PCR sensitivity by subsequent dot blot hybridization reduced one of the main advantages of PCR, i.e., expeditious diagnosis. Cervical scrapes were less sensitive than biopsies (13.6 versus 53%), although with four (6.1%) patients with intraepithelial neoplasias, HPV DNA was identified only by means of cervical scraping. We conclude that obtaining biopsy specimens and cervical scraping are complementary sampling procedures.  相似文献   
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An encoding technique called multilevel block truncation coding that preserves the spatial details in digital images while achieving a reasonable compression ratio is described. An adaptive quantizer-level allocation scheme which minimizes the maximum quantization error in each block and substantially reduces the computational complexity in the allocation of optimal quantization levels is introduced. A 3.2:1 compression can be achieved by the multilevel block truncation coding itself. The truncated, or requantized, data are further compressed in a second pass using combined predictive coding, entropy coding, and vector quantization. The second pass compression can be lossless or lossy. The total compression ratios are about 4.1:1 for lossless second-pass compression, and 6.2:1 for lossy second-pass compression. The subjective results of the coding algorithm are quite satisfactory, with no perceived visual degradation  相似文献   
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Positive N-periodic descriptor control systems   总被引:3,自引:0,他引:3  
A small-gain theorem is presented for almost global stability of monotone control systems which are open-loop almost globally stable, when constant inputs are applied. The theorem assumes “negative feedback” interconnections. This typically destroys the monotonicity of the original flow and potentially destabilizes the resulting closed-loop system.  相似文献   
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Thermal infrared data of the Digital Airborne Imaging Spectrometer (DAIS), whose channels 74-79 are in the 8-13 w m waveband region, were analysed with the aim of recovering land surface temperature (LST). DAIS images were acquired over an experimental site where field and laboratory emissivity measurements were performed, and these were used to recover the LST from the six DAIS thermal channels. Atmospheric correction of DAIS data was calculated by means of a nearby radiosounding and a radiative transfer model. DAIS derived LSTs were compared with ground measurements of LST made coincidentally for a few test fields, the central DAIS channels yielding temperatures up to 10°C higher than ground measurements. A linear calibration was performed using in situ measurements of temperature and emissivity for two reference fields, and the large differences in temperature were then considerably reduced. Temperatures obtained from DAIS channel 79 agreed with the in situ measurements within - 2°C. This channel seemed the most reliable for deriving accurate LSTs in the dataset analysed here.  相似文献   
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