用于制导弹药的自适应自动驾驶仪设计

传统制导弹药自动驾驶仪的设计要求精确的气动模型,并依赖于变增益(gainschedule),以说明系统的非线性.本文给出了一种简化自动驾驶仪设计程序的方法:在单一飞行条件下设计逆控制器,将逆控制器与在线神经网络组合,以说明因近似逆引起的误差,这样减少了大量设计程序及精确的气动数据.这些数据在大攻角或其它情况下很重要,因为这些领域中的空气动力特征变得高度非线性化.研究发现:逆的选择在其实现的过程中很重要,所以详细讨论.最后,给出该方法在非线性6自由度制导弹药中的模拟结果.     

Molecular Docking Studies and Biological Evaluation of Berberine–Benzothiazole Derivatives as an Anti-Influenza Agent via Blocking of Neuraminidase

In this study, we have introduced newly synthesized substituted benzothiazole based berberine derivatives that have been analyzed for their in vitro and in silico biological properties. The activity towards various kinds of influenza virus strains by employing the cytopathic effect (CPE) and sulforhodamine B (SRB) assay. Several berberine–benzothiazole derivatives (BBDs), such as BBD1, BBD3, BBD4, BBD5, BBD7, and BBD11, demonstrated interesting anti-influenza virus activity on influenza A viruses (A/PR/8/34, A/Vic/3/75) and influenza B viral (B/Lee/40, and B/Maryland/1/59) strain, respectively. Furthermore, by testing neuraminidase activity (NA) with the neuraminidase assay kit, it was identified that BBD7 has potent neuraminidase activity. The molecular docking analysis further suggests that the BBD1–BBD14 compounds’ antiviral activity may be because of interaction with residues of NA, and the same as in oseltamivir.     

粉末橡胶

介绍了Adar自主研制的Aparene NBR胶粉的特性、加工方法。特别对其改性PVC和PF的优越性，分别用其鞋类、电气绝缘板、摩擦衬片等产品所体现出来的各项优异性能做出充分说明。其在橡胶工业上的应用以制作胶粘剂为例，阐述了使用胶粉可改革加工方法，摈弃密炼机，节省能源等诸多的优点。     

Differentiating seawater and groundwater sulfate attack in Portland cement mortars

The study reported in this article deals with understanding the physical, chemical and microstructural differences in sulfate attack from seawater and groundwater. Portland cement mortars were completely immersed in solutions of seawater and groundwater. Physical properties such as length, mass, and compressive strength were monitored periodically. Thermal analysis was used to study the relative amounts of phases such as ettringite, gypsum, and calcium hydroxide, and microstructural studies were conducted by scanning electron microscopy. Portland cement mortars performed better in seawater solution compared to groundwater solution. The difference in performance could be attributed to the reduction in the quantity of the expansive attack products (gypsum and ettringite). The high Cl concentration of seawater could have played an important role by binding the C₃A to form chloroaluminate compounds, such as Friedel's salt (detected in the microstructural studies), and also by lowering the expansive potential of ettringite. Furthermore, the thicker layer of brucite forming on the specimens in seawater could have afforded better protection against ingress of the solution than in groundwater.     

IEVCA: An efficient image encryption technique for IoT applications using 2-D Von-Neumann cellular automata

Multimedia Tools and Applications - Present era is marked by exponential growth in transfer of multimedia data through internet. Most of the Internet-of-Things(IoT) applications send images to...     

Emergence of Gold‐Mesoporous Silica Hybrid Nanotheranostics: Dox‐Encoded,Folate Targeted Chemotherapy with Modulation of SERS Fingerprinting for Apoptosis Toward Tumor Eradication

Strategically fabricated theranostic nanocarrier delivery system is an unmet need in personalized medicine. Herein, this study reports a versatile folate receptor (FR) targeted nanoenvelope delivery system (TNEDS) fabricated with gold core silica shell followed by chitosan–folic acid conjugate surface functionalization by for precise loading of doxorubicin (Dox), resembled as Au@SiO₂‐Dox‐CS‐FA. TNEDS possesses up to 90% Dox loading efficiency and internalized through endocytosis pathway leading to pH and redox‐sensitive release kinetics. The superior FR‐targeted cytotoxicity is evaluated by the nanocarrier in comparison with US Food and Drug Administration (FDA)‐approved liposomal Dox conjugate, Lipodox. Moreover, TNEDS exhibits theranostic features through caspase‐mediated apoptosis and envisages high surface plasmon resonance enabling the nanoconstruct as a promising surface enhanced Raman scattering (SERS) nanotag. Minuscule changes in the biochemical components inside cells exerted by the TNEDS along with the Dox release are evaluated explicitly in a time‐dependent fashion using bimodal SERS/fluorescence nanoprobe. Finally, TNEDS displays superior antitumor response in FR‐positive ascites as well as solid tumor syngraft mouse models. Therefore, this futuristic TNEDS is expected to be a potential alternative as a clinically relevant theranostic nanomedicine to effectively combat neoplasia.     

Classification of patterns representing Apples and Oranges in three-qubit system

The study of the classification of Apples and Oranges in a warehouse has been undertaken in a three-qubit system using the method of repeated iterations in Grover’s algorithm and Ventura’s algorithm separately. Operator describing an inversion about average has been constructed as a square matrix of order eight, the phase inversion operators and corresponding iteration operators for patterns separately representing Apples and Oranges have been derived, and various possible superpositions as the choice for search states for the classification of these patterns have been obtained for starting states consisting of two patterns and a single pattern, respectively. It has been demonstrated that on the second iteration of the exclusion superposition by the corresponding iteration operators, the patterns Apples and Oranges, respectively, are most suitably classified using the Grover’s algorithm. The probabilities of classifications of Apples have also been calculated by using Ventura’s algorithm (Ventura and Martinez in Inf Sci 124:273–296, 2000; Found Phys Lett 12:547–559, 1999) for all the possible superpositions as the search states, and the results have been compared with those of Grover’s algorithm and it has been demonstrated that in general for classification of a given pattern (Apples) in three-qubit system, the Grover’s and Ventura’s algorithms are effective in the cases where the number of patterns in the stored database is larger or smaller, respectively.     

Effect of fiber orientation on the structural behavior of FRP wrapped concrete cylinders

In this study, 27 concrete cylinders with a diameter of 152.4 and a height of 304.8 mm were prepared. Among them, 18 cylinders were wrapped using two layers of fiber reinforced polymer (FRP) with six fiber orientations; six cylinders were wrapped using four layers of FRP with fibers in axial or hoop direction only; the remaining three cylinders were used as control. The FRP used was E-glass fiber reinforced ultraviolet (UV) curing vinyl ester. Fifteen coupon specimens were prepared to experimentally determine the tensile strength of the FRP with fibers oriented at 0°, 45°, and 90° from the loading direction. Co-axial compression tests were conducted on the wrapped cylinders and control cylinders. The test results were compared with existing confinement models. It is found that the strength, ductility, and failure mode of FRP wrapped concrete cylinders depend on the fiber orientation and wall thickness. Fibers oriented at a certain angle in between the hoop direction and axial direction may result in strength lower than fibers along hoop or axial direction. A larger database is desired in order to refine the existing design-oriented confinement models.     

Investigating the multi-causal and complex nature of the accident causal influence of construction project features

Construction project features (CPFs) are organisational, physical and operational attributes that characterise construction projects. Although previous studies have examined the accident causal influence of CPFs, the multi-causal attribute of this causal phenomenon still remain elusive and thus requires further investigation. Aiming to shed light on this facet of the accident causal phenomenon of CPFs, this study examines relevant literature and crystallises the attained insight of the multi-causal attribute by a graphical model which is subsequently operationalised by a derived mathematical risk expression that offers a systematic approach for evaluating the potential of CPFs to cause harm and consequently their health and safety (H&S) risk implications. The graphical model and the risk expression put forth by the study thus advance current understanding of the accident causal phenomenon of CPFs and they present an opportunity for project participants to manage the H&S risk associated with CPFs from the early stages of project procurement.