Robust and stable flow shop scheduling with unexpected arrivals of new jobs and uncertain processing times

In real scheduling problems, some disruptions and unexpected events may occur. These disruptions cause the initial schedule to quickly become infeasible and non-optimal. In this situation, an appropriate rescheduling method should be used. In this paper, a new approach has been proposed to achieve stable and robust schedule despite uncertain processing times and unexpected arrivals of new jobs. This approach is a proactive–reactive method which uses a two-step procedure. In the first step an initial robust solution is produced proactively against uncertain processing times using robust optimization approach. This initial robust solution is more insensitive against the fluctuations of processing times in future. In the next step, when an unexpected disruption occurs, an appropriate reactive method is adopted to deal with this unexpected event. In fact, in the second step, the reactive approach determines the best modified sequence after any unexpected disruption based on the classical objective and performance measures. The robustness measure is implemented in the reactive approach to increase the performance of the real schedule after disruption. Computational results indicate that this method produces better solutions in comparison with four classical heuristic approaches according to effectiveness and performance of solutions.     

Effect of nano-sized calcium carbonate on cure kinetics and properties of polyester/epoxy blend powder coatings

Today's strict environmental laws pose significant challenges for coating's formulators to look for eco-friendly products. Powder coatings, particularly polyester/epoxy blends have demonstrated their ability as alternatives to traditional solvent-borne coatings. Recently, the use of nanoparticles such as nano-CaCO₃ (nCaCO₃) has been suggested as a beneficial strategy towards powder coating application with improved properties. Here, we study the effect of nCaCO₃ on morphology, cure behavior, adhesion and hardness of polyester/epoxy systems. The nanoparticles shape, size and dispersion state were investigated through X-ray diffraction (XRD), transmission electron microscopy (TEM) and scanning electron microscopy (SEM) methods. Furthermore, isothermal cure characterization of the neat and filled systems was performed using a torque rheometer. The most important finding based on the rheological studies was the catalytic effect of nCaCO₃ on cure reaction of polyester/epoxy, leading to the shorter curing time. Moreover, the kinetic analyses of rheograms revealed a marked decrease in the activation energy of the cure process upon raising nCaCO₃ content. Interestingly, pull-off adhesion and hardness tests showed that the hardness and adhesion strength were dramatically increased by the addition of nCaCO₃ into the polyester/epoxy system compared to pure blend resin. Therefore, considering the strong competition in powder coating market, the use of nCaCO₃ as a commercial and inexpensive nanofiller is necessary not only to reduce the dwell time which has benefits in terms of the energy consumption and economics, but also to improve the performance of final polyester/epoxy coating.     

Value stream mapping approach and analytical network process to identify and prioritize production system’s Mudas (case study: natural fibre clothing manufacturing company)

The current research has been done to identify and prioritize the Mudas of the production line of a natural fibre clothing manufacturing company; in this way, value stream mapping has been used to identify the Mudas, then analytical hierarchy method has been used to screen the Mudas. In the first step, necessary information to design value stream of production process has been obtained by observation, measurement and interview; afterward, according to the obtained information and by forming a focus group, Mudas in the production line have been identified and prioritized according to seven categories of Mudas. In order to prioritizing the Mudas by the usage of analytical hierarchy method, the Super Decision software has been applied. Then, according to the obtained priorities, suggested map of the future value system has been drawn and some suggestions have been presented to eliminate Mudas and move towards the lean manufacturing.     

Regulated state synchronization of homogeneous multiagent systems with partial‐state coupling via low‐gain adaptive protocol

This paper studies regulated state synchronization for continuous‐time homogeneous multiagent systems with weakly unstable agents where the reference trajectory is given by a so‐called exosystem. The agents share part of their state over a communication network. We assume that the communication topology is completely unknown and directed. An algebraic Riccati equation–based low‐gain adaptive nonlinear dynamic protocol design is presented to achieve the regulated state synchronizations. Utilizing the adaptive control, our nonlinear dynamic protocol is universal and does not depend on any information about the communication topology or the number of agents.     

Spatial time-dependent reliability analysis of reinforced concrete slab bridges subject to realistic traffic loading

Resistance and loads are often correlated in time and space. The paper assesses the influence of these correlations on structural reliability/probability of failure for a typical two-lane reinforced concrete (RC) slab bridge under realistic traffic loading. Spatial variables for structural resistance are cover and concrete compressive strength, which in turn affect the strength and chloride-induced corrosion of RC elements. Random variables include pit depth and model error. Correlation of weights between trucks in adjacent lanes and inter-vehicle gaps are also included and are calibrated against weigh-in-motion data. Reliability analysis of deteriorating bridges needs to incorporate uncertainties associated with parameters governing the deterioration process and loading. One of the major unanswered questions in the work carried out to date is the influence of spatial variability of load and resistance on failure probability. Spatial variability research carried out to date has been mainly focused on predicting the remaining lifetime of a corroding structure and spatial variability of material, dimensional and environmental properties. A major shortcoming in the work carried out to date is the lack of an allowance for the spatial variability of applied traffic loads. In this article, a two-dimensional (2D) random field is developed where load effects and time-dependent structural resistance are calculated for each segment in the field. The 2D spatial time-dependent reliability analysis of an RC slab bridge found that a spatially correlated resistance results in only a small increase in probability of failure. Despite the fact that load effect at points along the length of a bridge is strongly correlated, the combined influence of correlation in load and resistance on probability of failure is small.     

The Effect of Sodium Dodecyl Sulfate (SDS) and Cetyltrimethylammonium Bromide (CTAB) on the Properties of ZnO Synthesized by Hydrothermal Method

ZnO nanostructures were synthesized by hydrothermal method using different molar ratios of cetyltrimethylammonium bromide (CTAB) and Sodium dodecyl sulfate (SDS) as structure directing agents. The effect of surfactants on the morphology of the ZnO crystals was investigated by field emission scanning electron microscopy (FESEM) and transmission electron microscopy (TEM) techniques. The results indicate that the mixture of cationic-anionic surfactants can significantly modify the shape and size of ZnO particles. Various structures such as flakes, sheets, rods, spheres, flowers and triangular-like particles sized from micro to nano were obtained. In order to examine the possible changes in other properties of ZnO, characterizations like powder X-ray diffraction (PXRD), thermogravimetric and differential thermogravimetric analysis (TGA-DTG), FTIR, surface area and porosity and UV-visible spectroscopy analysis were also studied and discussed.     

Splenocaval shunting for alleviation of portal hypertension in a dog: a case report

To demonstrate the usefulness of in vivo 31P nuclear magnetic resonance spectroscopy (MRS) in the diagnosis of ischemic heart disease, major findings from three clinical cardiac MRS investigations performed at our institute are summarized. The first study investigated whether 31P MRS with handgrip exercise testing could detect myocardial ischemia demonstrated by exercise 201Tl scintigraphy. Contrary to findings in normal subjects or patients with fixed thallium defects, the ratio of phosphocreatine (PCr) to ATP decreased significantly during exercise in patients with reversible thallium defects. In the second study, PCr and ATP content was measured by 31P MRS and compared in human myocardium with reversible ischemia or scar diagnosed by exercise thallium scintigraphy. Although the PCr content decreased in patients with either reversible or fixed thallium defects, the ATP content decreased only in the latter group. In the third study, postischemic myocardium with chronic mechanical dysfunction that exhibits recovery after revascularization in left ventriculography was metabolically characterized using quantitative cardiac 31P MRS. Postischemic myocardium with reversible mechanical dysfunction demonstrated reduced PCr but normal ATP content. These results suggest that 31P MRS is a clinically important method both for the detection of myocardial ischemia and in the evaluation of myocardial viability.     

Insulin stimulates pp120 endocytosis in cells co-expressing insulin receptors

pp120, a substrate of the insulin receptor tyrosine kinase, is a plasma membrane glycoprotein that is expressed in the hepatocyte as two spliced isoforms differing by the presence (full-length) or absence (truncated) of most of the intracellular domain including all phosphorylation sites. Co-expression of full-length pp120, but not its phosphorylation-defective isoforms, increased receptor-mediated insulin endocytosis and degradation in NIH 3T3 fibroblasts. We, herein, examined whether internalization of pp120 is required to mediate its effect on insulin endocytosis. The amount of full-length pp120 expressed at the cell surface membrane, as measured by biotin labeling, markedly decreased in response to insulin only when insulin receptors were co-expressed. In contrast, when phosphorylation-defective pp120 mutants were co-expressed, the amount of pp120 expressed at the cell surface did not decrease in response to insulin. Indirect immunofluorescence analysis revealed that upon insulin treatment of cells co-expressing insulin receptors, full-length, but not truncated, pp120 co-localized with alpha-adaptin in the adaptor protein complex that anchors endocytosed proteins to clathrin-coated pits. This suggests that full-length pp120 is part of a complex of proteins required for receptor-mediated insulin endocytosis and that formation of this complex is regulated by insulin-induced pp120 phosphorylation by the receptor tyrosine kinase. In vitro GST binding assays and co-immunoprecipitation experiments in intact cells further revealed that pp120 did not bind directly to the insulin receptor and that its association with the receptor may be mediated by other cellular proteins.     

Squared‐down passivity–based state synchronization of homogeneous continuous‐time multiagent systems via static protocol in the presence of time‐varying topology

This paper studies state synchronization of homogeneous multiagent systems (MAS) via a static protocol with partial‐state coupling in the presence of a time‐varying communication topology, which includes general time‐varying graphs as well as switching graphs. If the agents are squared‐down passive or squared‐down passifiable (via static output feedback or static input feedforward), then a static protocol can be designed for balanced, time‐varying graphs. Moreover, this static protocol works for arbitrary switching directed graphs if the agents are squared‐down minimum phase with relative degree one. The static protocol is designed for each agent such that state synchronization is achieved without requiring exact knowledge about the time‐varying network.