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排序方式: 共有385条查询结果,搜索用时 18 毫秒
1.
Alberto Ballesteros Ester Laguna-Gutierrez Paula Cimavilla-Roman Maria Luisa Puertas Antonio Esteban-Cubillo Julio Santaren Miguel Angel Rodriguez-Perez 《应用聚合物科学杂志》2021,138(46):51373
In the present work blends of polystyrene (PS) with sepiolites have been produced using a melt extrusion process. The dispersion degree of the sepiolites in the PS has been analyzed by dynamic shear rheology and X-ray micro-computed tomography. Sepiolites treated with quaternary ammonium salts (O-QASEP) are better dispersed in the PS matrix than natural sepiolites (N-SEP) or sepiolites organo-modified with silane groups (O-SGSEP). A percolated network is obtained when using 6.0 wt% of O-QASEP, 8.0 wt% of N-SEP and 10.0 wt% of O-SGSEP. It has been shown that multiple extrusion processes have a negative effect on the polymer architecture. They produce a reduction in the length of the polymeric chains, and they do not lead to a better dispersion of the particles in the polymer matrix. Foams have been produced using a gas dissolution foaming process, where a strong effect of the dispersion degree on the cellular structure of the different foams was found. The effects on the cellular structure obtained by using different types of sepiolites, different contents of sepiolites and different extrusion conditions have been analyzed. The foams produced with the formulations containing O-QASEP present the lowest cell size and the most homogeneous cellular structures. 相似文献
2.
Interference from digital signals in multipair cables has been shown to be cyclostationary under some conditions. This work evaluates the performance of a decision feedback equalizer (DFE) in the presence of cyclostationary interference (CI), intersymbol interference (ISI), and additive white noise (AWN). A comparison between a DFE with CI and one with stationary interference (SI) shows the ability of the DFE to substantially suppress CI. Fractionally spaced and symbol-rate DFE equalizers are also compared and the former is found to yield better performance, especially in the presence of CI. The use of a symbol-rate DFE using an adaptive timing technique that finds the receiver's best sampling phase is proposed for when the fractionally spaced DFE cannot be used because of its complexity. The results also demonstrate the potential benefits of synchronizing central office transmitter clocks, if a fractionally spaced DFE is used at the receiver 相似文献
3.
Non-parametric maximum-likelihood channel estimator and detector for OFDM in presence of interference 总被引:1,自引:0,他引:1
A maximum-likelihood channel estimator for the orthogonal frequency division multiplexing communication environments, in the presence of interference is discussed here. In a training-based scenario, the channel is estimated based on pilots that precede the transmission of the information. To reduce the number of estimation parameters, the channel is estimated iteratively in time-domain. Since interference from other users provide no useful information, parameters of the interference are neither estimated nor the effect of the interference neglected, instead interference along with Gaussian noise is perceived as non-Gaussian noise process. The algorithm assumes no a priori knowledge about the interfering channel and signal at the receiver, further no assumption on the statistical properties of the interferer is assumed, which makes this algorithm robust. The estimated channel information along with the estimated distribution are then utilised to equalise the subsequent data blocks. The strength of the algorithm is in its robustness to both synchronous and asynchronous interference, which is confirmed by the simulation results for both flat and multipath fading channels in presence of synchronous and asynchronous interference. 相似文献
4.
Proposes a more structured form of presupervisory preparation than generally exists in graduate training programs. Guidelines for incorporating such instruction are provided. Topics for discussion, including salient issues and perspectives in the supervision literature as well as research findings, are outlined. Potential pitfalls and strategies for trainees to deal with dissatisfactions are identified. The suggested curriculum for preparing the supervisee would cover the differences between a didactic and a therapeutic emphasis, stages of development within supervision, interpersonal relationships, and countertransference and parallel process. An overview of supervisory methods, especially with respect to the presentation of case material would also be valuable. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
5.
Carmen de Jesús-Gil Lídia Sans-de San Nicols Ester Ruiz-Romeu Marta Ferran Laura Soria-Martínez Irene García-Jimnez Anca Chiriac Josep Manel Casanova-Seuma Josep Manel Fernndez-Armenteros Sherry Owens Antonio Celada Michael D. Howell Ramn María Pujol Luis Francisco Santamaria-Babí 《International journal of molecular sciences》2021,22(4)
Candida albicans (CA) infections have been associated with psoriasis onset or disease flares. However, the integrated immune response against this fungus is still poorly characterized in psoriasis. We studied specific immunoglobulins in plasma and the CA response in cocultures of circulating memory CD45RA− cutaneous lymphocyte antigen (CLA)+/− T cell with autologous epidermal cells from plaque and guttate psoriasis patients (cohort 1, n = 52), and also healthy individuals (n = 17). A complete proteomic profile was also evaluated in plaque psoriasis patients (cohort 2, n = 114) regarding their anti-CA IgA levels. Increased anti-CA IgA and IgG levels are present in the plasma from plaque but not guttate psoriasis compared to healthy controls. CA cellular response is confined to CLA+ T cells and is primarily Th17. The levels of anti-CA IgA are directly associated with CLA+ Th17 response in plaque psoriasis. Proteomic analysis revealed distinct profiles in psoriasis patients with high anti-CA IgA. C-C motif chemokine ligand 18, chitinase-3-like protein 1 and azurocidin were significantly elevated in the plasma from plaque psoriasis patients with high anti-CA levels and severe disease. Our results indicate a mechanism by which Candida albicans exposure can trigger a clinically relevant IL-17 response in psoriasis. Assessing anti-CA IgA levels may be useful in order to evaluate chronic psoriasis patients. 相似文献
6.
Margaret Ottaviano Emilio Francesco Giunta Marianna Tortora Marcello Curvietto Laura Attademo Davide Bosso Cinzia Cardalesi Mario Rosanova Pietro De Placido Erica Pietroluongo Vittorio Riccio Brigitta Mucci Sara Parola Maria Grazia Vitale Giovannella Palmieri Bruno Daniele Ester Simeone 《International journal of molecular sciences》2021,22(7)
As widely acknowledged, 40–50% of all melanoma patients harbour an activating BRAF mutation (mostly BRAF V600E). The identification of the RAS–RAF–MEK–ERK (MAP kinase) signalling pathway and its targeting has represented a valuable milestone for the advanced and, more recently, for the completely resected stage III and IV melanoma therapy management. However, despite progress in BRAF-mutant melanoma treatment, the two different approaches approved so far for metastatic disease, immunotherapy and BRAF+MEK inhibitors, allow a 5-year survival of no more than 60%, and most patients relapse during treatment due to acquired mechanisms of resistance. Deep insight into BRAF gene biology is fundamental to describe the acquired resistance mechanisms (primary and secondary) and to understand the molecular pathways that are now being investigated in preclinical and clinical studies with the aim of improving outcomes in BRAF-mutant patients. 相似文献
7.
Tracy Q. Gardner Ana I. Flores Richard D. Noble John L. Falconer 《American Institute of Chemical Engineers》2002,48(6):1155-1167
A transient permeation method presented here not only determines the adsorption and diffusion properties of the pores that are the transport pathways through zeolite membranes, but nondestructively estimates the effective thickness of the membrane. Transient responses of the permeate concentration to step changes in the feed were measured on two H-ZSM-5 tubular membranes and modeled assuming Maxwell-Stefan diffusion and Langmuir adsorption. The adsorption isotherms determined from these transient measurements at 298 K of N2 and CO2 were nearly identical to those measured by calorimetry on H-ZSM-5 powders. The CH4 isotherm at 298 K was similar to isotherms measured by calorimetry and gravimetric techniques on Na-ZSM-5 and silicalite powders. The similarity of the isotherms indicates that transport of these light gases occurs mainly through zeolite pores. The Maxwell-Stefan diffusion coefficients DMS depended on concentration and were higher for higher feed partial pressures. Average DMS values for the two membranes were 7.5, 5 and 1.5×10−10 m2/s for N2, CH4, and CO2, respectively; these are in the same range and order as diffusion coefficients measured in zeolite crystals. 相似文献
8.
The widespread availability of digital learning resources in a variety of media formats offers the possibility to make a profound difference in education. This potential has not been fully realised for range of interrelated reasons. In this paper we study the key characteristics of learning resources that have proved effective in changing learning and teaching, and relate them to existing frameworks for understanding resources. We outline the relationships between resources, their users, and the way they are used, and explore issues that influence practitioners in choosing a particular resource. Our study is based on a review of resources for e-learning and chemistry in post-compulsory education, undertaken for the UK Joint Information Systems Committees (JISC), as part of a wider study examining ‘The Effectiveness of Resources, Tools and Support Services used by Tutors in Designing and Delivering E-Learning Activities’. 相似文献
9.
Ester Sporleder Yasmin Assan Shasha Rao David Warther Clive A. Prestidge Jean‐Olivier Durand Nicolas H. Voelcker 《Small (Weinheim an der Bergstrasse, Germany)》2017,13(29)
There is a pressing need to develop more effective therapeutics to fight cancer. An idyllic chemotherapeutic is expected to overcome drug resistance of tumors and minimize harmful side effects to healthy tissues. Antibody‐functionalized porous silicon nanoparticles loaded with a combination of chemotherapy drug and gold nanoclusters (AuNCs) are developed. These nanocarriers are observed to selectively deliver both payloads, the chemotherapy drug and AuNCs, to human B cells. The accumulation of AuNCs to target cells and subsequent exposure to an external electromagnetic field in the microwave region render them more susceptible to the codelivered drug. This approach represents a targeted two‐stage delivery nanocarrier that benefits from a dual therapeutic action that results in enhanced cytotoxicity. 相似文献
10.
Self‐Sealing Porous Silicon‐Calcium Silicate Core–Shell Nanoparticles for Targeted siRNA Delivery to the Injured Brain
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