Analyse von Lkw-Überholmanövern auf Autobahnen für die Entwicklung kooperativer Fahrerassistenzsysteme

Forschung im Ingenieurwesen - Lkw-Überholmanöver auf Autobahnen können Konfliktsituationen provozieren. Das lange Blockieren der Überholspur und plötzliche Ausscheren kann...     

A new approach to rheumatoid arthritis

Slow-acting antirheumatic drugs (SAARDs) are usually prescribed in rheumatoid arthritis only when non-steroid anti-inflammatory drugs can no longer suppress the inflammation or when articular damage is radiologically apparent. It was established recently that articular damage occurs in an early phase of RA. This damage is linked to subsequent disability; to prevent it is the purpose of SAARDs. In view of the short-term reduction of arthritis activity and improvement of function as well as the meanwhile established fact that the side effects of SAARDs are not different from those of other antirheumatic agents, SAARDs should be prescribed in an early phase of RA.     

Application of a leakage model to assess exfiltration from sewers.

The exfiltration of wastewater from sewer systems in urban areas causes a deterioration of soil and possibly groundwater quality. Beside the simulation of transport and degradation processes in the unsaturated zone and in the aquifer the analysis of the potential impact requires the estimation of quantity and temporal variation of wastewater exfiltration. Exfiltration can be assessed by the application of a leakage model. The hydrological approach was originally developed to simulate the interactions between the groundwater and surface water, it was adapted to allow for modelling of interactions between groundwater and sewer system. In order to approximate the exfiltration specific model parameters infiltration specific parameters were used as a basis. Scenario analysis of the exfiltration in the City of Dresden from 1997 to 1999 and during the flood event in August 2002 shows the variation and the extent of exfiltration rates.     

Age-related changes in cognitive ERPs of attenuation

The purpose of this article is to deliberate the moral and legal dilemma entailed in the weapon of the labour strike as a pressure tactic on the Israeli Finance Ministry regarding job slots, budgets and, in effect, violating the collective agreement signed by the nurses and impairing patients' treatment, as opposed to refraining from striking and suffering the heavy burden of work, the lack of trained personnel, low wages, and the inability to give patients proper, high quality treatment.     

Effect of postischemic reperfusion on microcirculation and lipid metabolism of skeletal muscle

To study the effect of ischemia reperfusion injury on microvascular reactivity and tissue metabolism in skeletal muscle, a Sprague-Dawley rat cremaster muscle was prepared as a tourniquet ischemia model and subjected to 2 hr ischemia followed by 1 hr reperfusion to simulate the timing of ischemia during microvascular surgery. The dose-response curve of arteriolar reactivity to norepinephrine, lipid peroxidation, and ultrastructure of capillaries was determined in both the control and postischemic reperfusion stages. Judging from the results, we summarize our observations as follows: (1) Postischemic reperfusion significantly increased arteriolar reactivity to norepinephrine, in which the EC50 for vasoconstriction decreased in all three orders of arterioles. These results suggest that reperfusion could have impaired the vasodilation control mechanism, possibly being endothelium dependent. (2) Lipid peroxidation increased sixfold in the reperfusion group, suggesting that oxygen free radicals have produced significant tissue damage under the created conditions. (3) Significant endothelial damage in the capillaries shown by electron microscope observation supports these studies, indicating that ischemia/reperfusion in clinically transplanted skeletal muscles could cause significant damage to the tissue microcirculation both physiologically and metabolically.