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Fatemighomi Hamideh Sadat Golalizadeh Mousa Amani Meisam 《Pattern Analysis & Applications》2022,25(2):467-481
Pattern Analysis and Applications - Efficient high-dimensional analyses of hyperspectral datasets and their utilization within classification algorithms is a popular topic in the field of data... 相似文献
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Marziyeh Hayati Ghasem Rezanejade Bardajee Majid Ramezani Samaneh Sadat Hosseini Farhang Mizani 《Polymer International》2020,69(2):156-164
Hydrogels, nanogels and nanocomposites show increasing potential for application in drug delivery systems due to their good chemical and physical properties. Therefore, we were encouraged to combine them to produce a new compound with unique properties for a long‐term drug release system. In this regard, the design and application of a nanocomposite hydrogel containing entrapped nanogel for drug delivery are demonstrated. To this aim, we first prepared an iron oxide nanocomposite nanogel based on poly(N‐isopropylacrylamide)‐co‐((2‐dimethylaminoethyl) methacrylate) (PNIPAM‐co‐PDMA) grafted onto sodium alginate (NaAlg) as a biocompatible polymer and iron oxide nanoparticles (ION) as nanometric base (PND/ION‐NG). This was then added into a solution of PDMA grafted onto NaAlg. Through dropwise addition of mixed aqueous solution of iron salts into the prepared polymeric solution, a novel hydrogel nanocomposite with excellent pH, thermal and magnetic responsivity was fabricated. The synthesized samples were fully characterized using Fourier transform infrared spectroscopy, thermogravimetric analysis, scanning electron microscopy with energy‐dispersive X‐ray analysis, vibrating sample magnetometry and atomic force microscopy. A mechanism for the formation of PNIPAM‐co‐PDMA/NaAlg‐ION nanogel–PDMA/NaAlg‐ION hydrogel and PND/ION nanogel is suggested. Swelling capacity was measured at various temperatures (25 to 45 °C), pH values (from 2 to 11) and magnetic field and under load (0.3 psi) and the dependence of swelling properties of the nanogel–hydrogel nanocomposite on these factors was well demonstrated. The release rate of doxorubicin hydrochloride (DOX) as an anticancer drug was studied at different pH values and temperatures in the presence and absence of a magnetic field. The results showed that these factors have a high impact on drug release from this nanocomposite. The result showed that DOX release could be sustained for up to 12.5 days from these nanocomposite hydrogels, significantly longer than that achievable using the constituent hydrogel or nanogel alone (<1 day). The results indicated that the nanogel–hydrogel nanocomposite can serve as a novel nanocarrier for anticancer drug delivery. © 2019 Society of Chemical Industry 相似文献
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The dehydroalkylation of toluene with ethane to the isomeric ethyltoluenes was studied on 0.4Pt/H-ZSM-5 at varying contact
times (1/WHSV). At a high contact time of 1.0 h, toluene disproportionation and hydrogenolysis reactions dominate, resulting
in low selectivity to the desired ethyltoluenes via the alkylation reaction. However, at a low contact time of 0.12 h side
reactions are eliminated, resulting in maximum selectivities to the kinetically favored ethyltoluenes and hydrogen. Results
at high selectivities to ethyltoluenes provide significant insight into reaction pathways. 相似文献
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Fariba Zerafati Shoja Hudsa Majidian Leila Nikzad 《International Journal of Applied Ceramic Technology》2021,18(4):1174-1182
In the present work, particle arrangement and their packing in the sediment layer of zirconia suspension were studied. To evaluate the particle settling, aqueous suspensions of zirconia nanoparticles were prepared in different dispersion states. In one state, Dolapix CE64 was used as a dispersant to provide electrosteric mechanism. In another state, pH of the suspension was adjusted at 4 to provide electrostatic mechanism. The other state was the combination of dispersant and pH adjustment which resulted in the most stable suspension. First of all, the stability of all dispersion states was evaluated by zeta potential, sediment volume (SV) and height, viscosity, and packing density (PD). Then, the sediment layers of all suspensions were characterized. Incorporation of electrostatic mechanism was resulted in a main decrease in viscosity with high surface charges, while electrosteric mechanism caused lower sedimentation of particles. Fall velocities of particles/agglomerates were estimated, and the influences of dispersion states on the particles fall velocities were characterized. The microstructural observation revealed homogeneous packing of particles in the sediment layer of the stable suspension demonstrating the proper dispersion of particles. Dolapix CE64 and pH adjustment resulted in a uniform arrangement of particles without agglomeration and spherical and regular granules with a uniform shape. 相似文献
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Bahareh ZIBANEZHAD Kamran ZAMANIFAR Razieh Sadat SADJADY Yousef RASTEGARI 《浙江大学学报(英文版)(C辑:计算机与电子)》2011,12(9)
With the growing use of service-oriented architecture for designing next generation software systems,the service composition problem and its execution complexity have become even more important in resp... 相似文献
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