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排序方式: 共有189条查询结果,搜索用时 15 毫秒
1.
Marziyeh Hayati Ghasem Rezanejade Bardajee Majid Ramezani Samaneh Sadat Hosseini Farhang Mizani 《Polymer International》2020,69(2):156-164
Hydrogels, nanogels and nanocomposites show increasing potential for application in drug delivery systems due to their good chemical and physical properties. Therefore, we were encouraged to combine them to produce a new compound with unique properties for a long‐term drug release system. In this regard, the design and application of a nanocomposite hydrogel containing entrapped nanogel for drug delivery are demonstrated. To this aim, we first prepared an iron oxide nanocomposite nanogel based on poly(N‐isopropylacrylamide)‐co‐((2‐dimethylaminoethyl) methacrylate) (PNIPAM‐co‐PDMA) grafted onto sodium alginate (NaAlg) as a biocompatible polymer and iron oxide nanoparticles (ION) as nanometric base (PND/ION‐NG). This was then added into a solution of PDMA grafted onto NaAlg. Through dropwise addition of mixed aqueous solution of iron salts into the prepared polymeric solution, a novel hydrogel nanocomposite with excellent pH, thermal and magnetic responsivity was fabricated. The synthesized samples were fully characterized using Fourier transform infrared spectroscopy, thermogravimetric analysis, scanning electron microscopy with energy‐dispersive X‐ray analysis, vibrating sample magnetometry and atomic force microscopy. A mechanism for the formation of PNIPAM‐co‐PDMA/NaAlg‐ION nanogel–PDMA/NaAlg‐ION hydrogel and PND/ION nanogel is suggested. Swelling capacity was measured at various temperatures (25 to 45 °C), pH values (from 2 to 11) and magnetic field and under load (0.3 psi) and the dependence of swelling properties of the nanogel–hydrogel nanocomposite on these factors was well demonstrated. The release rate of doxorubicin hydrochloride (DOX) as an anticancer drug was studied at different pH values and temperatures in the presence and absence of a magnetic field. The results showed that these factors have a high impact on drug release from this nanocomposite. The result showed that DOX release could be sustained for up to 12.5 days from these nanocomposite hydrogels, significantly longer than that achievable using the constituent hydrogel or nanogel alone (<1 day). The results indicated that the nanogel–hydrogel nanocomposite can serve as a novel nanocarrier for anticancer drug delivery. © 2019 Society of Chemical Industry 相似文献
2.
Salehi Maryam Zavarian Ali Asghar Arman Ali Hafezi Fatemeh Rad Ghasem Amraee Mardani Mohsen Hamze Kooros Luna Carlos Naderi Sirvan Ahmadpourian Azin 《SILICON》2018,10(6):2743-2749
Silicon - The characterization of ion beam current density distribution and beam uniformity is crucial for improving broad-beam ion source technologies. The design of the broad ion beam extraction... 相似文献
3.
Microfluidic Manipulation of Core/Shell Nanoparticles for Oral Delivery of Chemotherapeutics: A New Treatment Approach for Colorectal Cancer
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Mohammad Mahdi Hasani‐Sadrabadi Shahrouz Taranejoo Erfan Dashtimoghadam Ghasem Bahlakeh Fatemeh Sadat Majedi Jules John VanDersarl Mohsen Janmaleki Fatemeh Sharifi Arnaud Bertsch Kerry Hourigan Lobat Tayebi Philippe Renaud Karl I. Jacob 《Advanced materials (Deerfield Beach, Fla.)》2016,28(21):4134-4141
4.
Amir Hossein Alavi Amir Hossein Gandomi Mohammad Ghasem Sahab Mostafa Gandomi 《Engineering with Computers》2010,26(2):111-118
This paper presents an alternative approach to formulation of soil classification by means of a promising variant of genetic programming (GP), namely multi expression programming (MEP). Properties of soil, namely plastic limit, liquid limit, color of soil, percentages of gravel, sand, and fine-grained particles are used as input variables to predict the classification of soils. The models are developed using a reliable database obtained from the previously published literature. The results demonstrate that the MEP-based formulas are able to predict the target values to high degree of accuracy. The MEP-based formulation results are found to be more accurate compared with numerical and analytical results obtained by other researchers. 相似文献
5.
Farzad Hashemzadeh Iraj Hassanzadeh Mahdi Tavakoli Ghasem Alizadeh 《Journal of Intelligent and Robotic Systems》2012,68(3-4):245-259
In this paper, we introduce a new adaptive controller design scheme for nonlinear telerobotic systems with varying time delays where the delays and their variation rates are unknown. The designed controller has the ability to synchronize the state behaviors of the local and the remote robots. In this paper, asymptotic stability in the presence of varying time delays is of interest. Using the proposed controller, asymptotic stability of the bilateral telerobotic system subject to any bounded yet unknown varying delay with a bounded yet unknown rate of change can be guaranteed. Besides the varying time delay, the proposed adaptive controller has the ability to adapt to the parameter variations in the local and the remote robots’ dynamics. It is shown that position and velocity errors between the local and the remote manipulators converge to the zero asymptotically, thus ensuring teleoperation transparency. Experimental and simulation results with a pair of PHANToM haptic devices and a pair of planar manipulators under varying time delays in the communication channel demonstrate the effectiveness of the proposed scheme. 相似文献
6.
This paper presents a novel approach for estimating the distribution of the incoming waves at the mobile unit antenna, i.e. the scattering distribution, in a typical micro-cellular system. This estimate is vital in determining many system parameters of interest as well as designing unbiased estimators for the velocity of mobile units in micro-cellular systems. The proposed approach deploys the zero-crossing rates of the quadrature components and the instantaneous frequency of the received signal at the mobile unit to estimate the scattering distribution. We also propose a new model for simulating multipath fading channels with non-isotropic scattering. We use the channel simulator to evaluate the performance of the proposed estimator for the scattering distribution. Simulation results show that proposed estimator exhibits small bias and root mean square error. 相似文献
7.
Ghasem Sargazi Daryoush Afzali Ali Ghafainazari Hamideh Saravani 《Journal of Inorganic and Organometallic Polymers and Materials》2014,24(4):786-790
Metal-organic framework (MOF) has been shown to potential applications due to the high porous hybrid structure. Cobalt MOF was synthesized rapidly by ultrasound energy with about 3,000 m2/g surface area by BET method. Furthermore, this component is crystalline with significant thermal stability, on account of X-ray diffraction and thermal analysis, respectively. Based on high roughness, crystallinity, and unreported type of FTIR spectrum, a new structure of Co-MOF structure was proposed. 相似文献
8.
Ali Ramezani Ghasem Najafpour Darzi Maedeh Mohammadi 《Korean Journal of Chemical Engineering》2011,28(4):1035-1041
Removal of melanoidin pigment from molasses spent wash was investigated using a new adsorbent. Solid adsorbents were fabricated
from charcoal fly ash and clay. The effect of various molasses concentration (6 to 12 g/l) on removal efficiency was studied. The obtained results revealed that maximum removal efficiency of 82% was achieved at
the molasses concentration of 6 g/l and contact time of 7 h. The saturated porous adsorbents were regenerated and reused to conduct similar experiments. The
achieved data showed that more than 90% of the capacity of the fresh adsorbent was recovered after regeneration. Various adsorption
isotherms of Langmuir, Freundlich, Temkin and Harkins-Jura were applied to interpret the obtained experimental data. The obtained
results revealed that the sorption data were well described by the Harkins-Jura model. Also, various kinetic models of pseudo-first
order, pseudo-second order, Elovich and intra-particle diffusion were used to predict the characteristic parameters which
are useful in process design. It was concluded that the best fit was obtained with pseudo-second order kinetic model at low
molasses concentrations. 相似文献
9.
Commitment is vital in inter-organizational relationships. It is important to understand what drives commitment which then affects the relationship between organizations. Commitment is a multidimensional construct and its dimensions can be broadly categorized into attitudinal and behavioural perspectives. In conventional practice, commitment researchers have tended to focus on the attitudinal perspective, while the behavioural perspective is largely ignored. In an attempt to buck that conventional trend commitment research is proposed along the unconventional but widely accepted as important behavioural perspective, building up a more complete understanding of the importance of behavioural commitment, as well as developing and validating a theoretical model that depicts precisely the relationship between behavioural commitment and its key driving factors. Accordingly a large-scale questionnaire survey has been conducted in the UK construction industry and 636 responses were collected. Structural equation modelling was then used to test the theoretical model. Results validate trust, reliance and dependence as the major antecedents of behavioural commitment. A new direction in commitment research adds new findings to the current body of commitment literature. 相似文献
10.
Effect of modified single‐wall carbon nanotubes on mechanical and morphological properties of thermoplastic elastomer nanocomposites based on (polyamide 6)/(acrylonitrile butadiene rubber)
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Thermoplastic elastomer nanocomposites based on acrylonitrile butadiene rubber (NBR) and polyamide 6 (PA6), with acid functionalized single‐wall carbon nanotubes (SWNT), were prepared via a direct melt‐mixing process in an internal mixer. The influence of SWNT content (0, 0.5, 1, 1.5) on morphological properties of PA6/NBR with different ratios (80/20, 70/30, 60/40) were then investigated. Characterization of nanocomposites was conducted by using transmission electron microscopy, scanning electron microscopy, differential scanning calorimetry, and mechanical properties. Scanning electron microscopy micrographs proved the droplet‐matrix blend morphology in which the size of NBR droplets decreased as the SWNT loading increased, suggesting dispersion of SWNT in the PA6 phase. It was further proved by transmission electron microscopy images, showing homogenous dispersion of SWNT in the PA6 phase. Differential scanning calorimetry results showed a slightly reduced percentage of crystallinity in samples containing SWNT. The mechanical properties of nanocomposites indicated an enhancement in tensile strength, modulus, and hardness on increasing SWNT content. J. VINYL ADDIT. TECHNOL., 22:336–341, 2016. © 2014 Society of Plastics Engineers 相似文献