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1.
Heloisa Martins Shih Mitchell M Tseng 《International Journal of Project Management》1996,14(6):373-378
In this paper the application of workflow technology to monitor, control and coordinate business processes and projects is proposed. The conceptual characteristics of processes and projects as well as their management needs in the functions of planning, execution, monitoring and control are compared. The general design of the proposed system is then developed, with an application example. The proposed monitoring and control system provides proactive tracking of the flow of work and information, and of the utilization and commitment of resources. The design supports hierarchical management of the project and/or business process, allowing concerned persons to visualize and to utilize it in different levels of abstraction, as necessary. The application of workflow technology also provides additional benefits in facilitating communication, documentation and re-utilization. 相似文献
2.
Manganese peroxidase and biomimetic systems applied to in vitro lignin degradation in Eucalyptus grandis milled wood and kraft pulps
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3.
Denise Bevilaqua Heloisa A. Acciari Fabiana A. Arena Assis V. Benedetti Cecílio S. Fugivara Germano Tremiliosi Filho Oswaldo Garcia Júnior 《Minerals Engineering》2009,22(3):254-262
In this work, the monitoring of the bacterial and chemical dissolution of bornite was evaluated using cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS); the mineral surface was examined using scanning electron microscopy (SEM) and atomic force microscopy (AFM). The analysis of CV results allowed attributing the different peaks observed in both direct and reverse potential scanning to the oxidation of bornite to a secondary covellite and its reduction via different non stoichiometric copper sulphides intermediaries. EIS data for bornite were obtained in control medium up to 78 h of immersion, when a cellular suspension of A. ferrooxidans was added and the experiments continued up to a 192 h of test. The EIS response was different when bacteria were added in the beginning of the test or after some hours of immersion in acid solution. The experiments were performed in different cell configurations and a model of the electrode/electrolyte interface. The correspondent equivalent electrical circuit was used to fit impedance spectra for all studied conditions. A common equivalent circuit used for corrosion processes where anodic (degradation of the mineral) and cathodic (oxygen reduction) reactions occur in parallel, together film and biofilm formation was proposed. 相似文献
4.
Milene N.O. Moritz Alyssa R. Merkel Ean G. Feldman Heloisa S. Selistre-de-Araujo Julie A. Rhoades 《International journal of molecular sciences》2021,22(13)
Integrins participate in the pathogenesis and progression of tumors at many stages during the metastatic cascade. However, current evidence for the role of integrins in breast cancer progression is contradictory and seems to be dependent on tumor stage, differentiation status, and microenvironmental influences. While some studies suggest that loss of α2β1 enhances cancer metastasis, other studies suggest that this integrin is pro-tumorigenic. However, few studies have looked at α2β1 in the context of bone metastasis. In this study, we aimed to understand the role of α2β1 integrin in breast cancer metastasis to bone. To address this, we utilized in vivo models of breast cancer metastasis to bone using MDA-MB-231 cells transfected with an α2 expression plasmid (MDA-OEα2). MDA cells overexpressing the α2 integrin subunit had increased primary tumor growth and dissemination to bone but had no change in tumor establishment and bone destruction. Further in vitro analysis revealed that tumors in the bone have decreased α2β1 expression and increased osteolytic signaling compared to primary tumors. Taken together, these data suggest an inverse correlation between α2β1 expression and bone-metastatic potential. Inhibiting α2β1 expression may be beneficial to limit the expansion of primary tumors but could be harmful once tumors have established in bone. 相似文献
5.
Discoloration process modeling by neural network 总被引:1,自引:0,他引:1
Oswaldo Luiz Cobra Guimares Marta Heloisa dos Reis Chagas Darcy Nunes Villela Filho Adriano Francisco Siqueira Hlcio Jos Izrio Filho Henrique Otvio Queiroz de Aquino Messias Borges Silva 《Chemical engineering journal (Lausanne, Switzerland : 1996)》2008,140(1-3):71-76
The photo-oxidation of acid orange 52 dye was performed in the presence of H2O2, utilizing UV light, aiming the discoloration process modeling and the process variable influence characterization. The discoloration process was modeled by the use of feedforward neural network. Each sample was characterized by five independent variables (dye concentration, pH, hydrogen peroxide volume, temperature and time of operation) and a dependent variable (absorbance). The neural model has also provided, through Garson Partition coefficients and the Pertubation method, the independent variable influence order determination. The results indicated that the time of operation was the predominant variable and reaction mean temperature was the lesser influent variable. The neural model obtained presented coefficients of correlation on the order 0.98, for sets of trainability, validation and testing, indicating the power of prediction of the model and its character of generalization. 相似文献
6.
Research of polynaphthalimides (PNI) frequently reports difficulties over synthesis and processing due to insolubility. In this work, we present a novel comprehensive study on the effects of time, temperature and catalyst on the synthesis of soluble PNI precursors—polyamic acids (PAAs)—, as well as a novel synthetic procedure for the synthesis of PNI using mild conditions. Kinetic studies concerning the monomer conversion and the degree of premature imidization were performed through proton nuclear magnetic resonance and gel permeation chromatography for temperature ranging from 25 to 100°C. High temperatures (above 60°C) entail extensive premature imidization and insolubility. The use of triethylamine also catalyzes imidization. At the optimal condition, soluble PAA precursors for PNI of 72 kDa could be obtained at 40°C in N-methyl-2-pyrrolidone solution (30 wt%) after 5 hr polymerization. 相似文献
7.
Fernanda Figueiredo Martins dos Santos Heloisa Cunha Furtado Luiz Henrique de Almeida 《Journal of Failure Analysis and Prevention》2018,18(4):809-818
The operating conditions of a power plant affect its structural integrity due to many degradation mechanisms, among which is creep. Strain measurements constitute a relatively simple and reliable method of obtaining accurate data regarding the capability of engineering materials to withstand loads and of determining stress distribution in all manner of structural components. This work carried out a critical evaluation of the application of a high-temperature strain gage on a strain and stress analysis. The sensor was undergoing a group of long-term creep tests whose results were compared with the creep machine’s acquisition system. The same strain gage was part of a monitoring system and its out some used on the remaining life evaluation a power plant’s pipeline. The methodology consists of online strain monitoring of those components or regions more susceptible to creep failure, which were identified by finite element analysis. The long-term creep tests using high-temperature strain gages showed that the relative position between sensor and the sample necking region exercises great influence on the measured results. Linear relationship between minimum creep rate obtained by strain gages and rupture time values was observed. The power plant pipeline analysis showed that thermomechanical fatigue is the predominant degradation mechanism. 相似文献
8.
The aim of this study was to evaluate the effects of the 5.25% sodium hypochlorite (NaOCl), 2% chlorhexidine (CHX), and MTAD solutions on the surface of gutta‐percha and Resilon cones by using atomic force microscopy (AFM). Accessory cones were washed and dried. The cones were randomly divided into six groups: gutta‐percha immersed in NaOCl, CHX, and MTAD, and Resilon immersed in NaOCl, CHX, and MTAD. AFM images of the same area were made in different periods of time. JPK? Image Processing Software was used to evaluate the images. The parameters used to evaluate the changes were RMS and line profiles. No statistically significant change was observed in the RMS values. The line profiles detected changes only for gutta‐percha surfaces after immersion in NaOCl and MTAD solutions. In conclusion, 5.25% NaOCl and MTAD are associated with local changes in surface roughness of gutta‐percha cones. No change was observed when 2% CHX was used. The use of all tested solutions did not produce any changes on Resilon surface. Microsc. Res. Tech. 75:791–795, 2012. © 2012 Wiley Periodicals, Inc. 相似文献
9.
Pyrolysis of sugarcane bagasse in a fixed bed reactor: Influence of operational conditions in the distribution of products
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10.
Carletto JS Roux KC Maltez HF Martendal E Carasek E 《Journal of hazardous materials》2008,157(1):88-93
This study presents the development of an on-line preconcentration system for zinc(II) determination in aqueous samples. The analyte was trapped in a mini-column filled with a chelating resin based on a chitosan biopolymer modified with 8-hydroxyquinoline obtained by the diazotization reaction. Flow and chemical variables of the system, as well as the potential interference ions, were optimized through a multivariate procedure. The factors selected were sample pH, eluent concentration (HNO(3)), and sample and eluent flow rates. It was verified through a full factorial design that the sample pH and eluent flow rate factors were statistically significant at the 95% confidence level. A final optimization of the significant factors was carried out using a Doehlert matrix. The preconcentration system was linear between 2.5 and 75 microgL(-1), with a regression coefficient of 0.9995. The enrichment factor was 17.6. The limits of detection and quantification were 0.8 and 2.5 microgL(-1), respectively. The repeatability and the analytical frequency were, respectively, 2.7 (25.0 microgL(-1), n=8) and 18 samples per hour. Results for recovery tests using mineral water samples were between 85 and 93%. Certified reference materials were analyzed in order to check the accuracy of the proposed method. 相似文献