Fuzzy-based hunger games search algorithm for global optimization and feature selection using medical data

Neural Computing and Applications - Feature selection (FS) is one of the basic data preprocessing steps in data mining and machine learning. It is used to reduce feature size and increase model...     

Force Curve Measurements with the AFM: Application to the In Situ Determination of Grafted Silicon-Wafer Surface Energies

The atomic force microscope (AFM) can be used to perform surface force measurements in the quasi-static mode (cantilever is not oscillating) to investigate nanoscale surface properties. Nevertheless, there is still a lack of literature proposing a complete systematic and rigorous experimental procedure that enables one to obtain reproducible and significant quantitative data. This article focuses on the fundamental experimental difficulties arising when making force curve measurements with the AFM in air. On the basis of this AFM calibration procedure, quantitative assessment values were used to determine, in situ, SAM (or Self Assembled Monolayer)-tip thermodynamic work of adhesion at a local scale, which have been found to be in good agreement with quoted values. Finally, determination of surface energies of functionalised silicon wafers (as received, CH₃, OH functionalised silicon wafers) with the AFM (at a local scale) is also proposed and compared with the values obtained by wettability (at a macroscopic scale). In particular, the effect of the capillary forces is discussed.     

Corticosteroids significantly delay the onset of docetaxel-induced fluid retention: final results of a randomized study of the European Organization for Research and Treatment of Cancer Investigational Drug Branch for Breast Cancer

PURPOSE: To confirm the efficacy of docetaxel in patients with breast cancer previously treated with one chemotherapy regimen for advanced or metastatic disease and to compare the incidence of fluid retention (FR) and skin toxicity when docetaxel is administered with and without prophylactic corticosteroids. PATIENTS AND METHODS: Eighty-three patients, pretreated with one chemotherapy regimen for metastatic breast cancer (MBC) with bidimensionally measurable and progressive disease, were eligible for this randomized trial. Docetaxel with prophylactic oral antihistamine was administered at a dose of 50 mg/m2 as a 1-hour infusion on days 1 and 8 every 21 days and patients were randomized to receive methylprednisolone (40 mg days -1, 0, 1, 7, 8, and 9 of each cycle) (arm A) or no methylprednisolone (arm B). RESULTS: Twenty-eight patients (34%, 95% confidence interval [CI], 23% to 45%) achieved on objective response. The median time to disease progression and median overall survival time were 5 and 13.5 months, respectively. In total, 415 cycles of docetaxel were administered (arm A: N = 219, median = six; arm B: N = 196, median = five). The most common toxicity observed was grade 3 or 4 neutropenia, which occurred in 79% of patients. Clinically significant nonhematologic side effects included skin reactions and asthenia. In an intent-to-treat analysis, patients who received methylprednisolone premedication had a delayed onset of FR (median time to onset of FR: arm A, 84 days; arm B, 62 days; P = .01) and received a higher median cumulative dose of docetaxel before the onset of FR (arm A, 333 mg/m2; arm B, 215 mg/m2; P = .001). There was no statistically significant difference in the incidence of skin toxicity between the two arms. CONCLUSION: Docetaxel, at this dose and schedule, has definite antitumor activity in pretreated MBC patients. Moreover, this is the first randomized trial to show that corticosteroids have a favorable impact on docetaxel-induced FR.     

Performance of Gradient-Based Optimizer for Optimum Wind Cube Design

Renewable energy is a safe and limitless energy source that can be utilized for heating, cooling, and other purposes. Wind energy is one of the most important renewable energy sources. Power fluctuation of wind turbines occurs due to variation of wind velocity. A wind cube is used to decrease power fluctuation and increase the wind turbine’s power. The optimum design for a wind cube is the main contribution of this work. The decisive design parameters used to optimize the wind cube are its inner and outer radius, the roughness factor, and the height of the wind turbine hub. A Gradient-Based Optimizer (GBO) is used as a new metaheuristic algorithm in this problem. The objective function of this research includes two parts: the first part is to minimize the probability of generated energy loss, and the second is to minimize the cost of the wind turbine and wind cube. The Gradient-Based Optimizer (GBO) is applied to optimize the variables of two wind turbine types and the design of the wind cube. The metrological data of the Red Sea governorate of Egypt is used as a case study for this analysis. Based on the results, the optimum design of a wind cube is achieved, and an improvement in energy produced from the wind turbine with a wind cube will be compared with energy generated without a wind cube. The energy generated from a wind turbine with the optimized cube is more than 20 times that of a wind turbine without a wind cube for all cases studied.     

The use of forest-derived specific gravity for the conversion of volume to biomass for open-grown trees on agricultural land

Accounting for agroforestry contributions to carbon sequestration and cellulosic feedstock production requires biomass equations that accurately estimate biomass in open-grown trees. Since equations for open-grown trees are rare and developing these is expensive, existing forest-based equations are an attractive alternative for open-grown trees in carbon accounting and biomass modeling. How accurate this alternative is depends on how similar the key attributes, such as specific gravity, trunk shape, and crown architecture, are between open- and forest-grown trees. We evaluated the use of forest-derived specific gravity for conversion of volume to biomass for morphologically distinct open-grown species: green ash, ponderosa pine, and eastern redcedar. Trunk biomass was consistently and significantly underestimated from 6.3% to 16.6% depending on species, indicating open-grown trees have greater trunk specific gravity than forest-grown counterparts within the same geographic region; however a conclusive difference in branch specific gravity was not found between open- and forest-grown trees. Open-grown trees have greater trunk specific gravity, sharper trunk taper, and larger crown. When forest-based equations are used for trunk biomass of open-grown trees, the greater trunk specific gravity results in underestimation; however, the sharper trunk taper results in overestimation. Studies are needed to examine whether the underestimation could be offset by the overestimation and how the larger crown affects biomass estimation when forest-based equations are used for open-grown trees. Our results provide an essential understanding to interpret the biometric relationship of open- to forest-grown trees and to develop an efficient means how forest-based equations might be best modified for open-grown trees.     

Geothermal resources in the Asal Region,Republic of Djibouti: An update with emphasis on reservoir engineering studies

Three independent geothermal systems have been identified, so far, in the Asal region of the Republic of Djibouti (i.e. Gale le Goma, Fiale and South of Lake). Six deep wells have been drilled in the region, the first two in 1975 and the others in 1987–88. Well A2 was damaged and wells A4 and A5 encountered impermeable yet very hot (340–365 °C) rocks. Wells A1, A2, A3 and A6 produce highly saline (120 g/L TDS) fluids leading to mineral scaling. Well test data indicate that the reservoir might be producing from fractured and porous zones. The estimated permeability-thickness of the deep Gale le Goma reservoir is in the 3–9 darcy-meter range. Lumped-parameter modeling results indicate that well A3 should be operated at about 20 kg/s total flow rate and that injection should be considered to reduce pressure drawdown. The estimated power generation potential of well A3 is 2.5 MWe, and that of all Asal high-temperature hydrothermal systems is between 115 and 329 MWe for a 25-year exploitation period.     

Determining factors that impact the calibration of consumer-grade digital cameras used for vegetation analysis

Digital cameras can collect quantitative leaf data, such as chlorophyll content and leaf area index (LAI), because they act as a simple broadband radiometer. However, a cross-calibration between cameras is needed for the purpose of extracting vegetation information from various image repositories. The objective of this study was to examine the variation between multiple consumer-grade camera types – single reflex lens (SLR), point-and-shoot, and cellphone cameras – for the purpose of collecting reliable quantitative data when monitoring vegetation. The specific objectives were to: 1) identify the optimal light conditions for the calibration procedure, 2) determine the variability of exposure value (EV)-corrected calibrated digital numbers (cDN_ev) values among eight consumer-grade digital cameras, and 3) compare the cDN_ev values with the raw digital numbers (DN), exposure-adjusted digital numbers (DN_ev), and calibrated digital numbers (cDN) as these latter three components are easier to compute. This study demonstrated that light intensity was important for calibrating cameras to ensure sensor saturation, and that an improper white-balance setting can negatively impact data collection. In one experiment, the coefficient of variation (CV) between the eight cameras examined in the study was reduced from 29% using raw DN to 16% using cDN_ev values. Likewise, the root mean square error in estimating leaf chlorophyll-a using a common vegetation index for digital camera, excess green index (EGI), was reduced from 131 to 96 mg g^?2. However, for both experiments, there was only a weak statistical difference between cDN_ev and DN_ev, indicating that exposure information was the most useful in minimizing the differences between cameras. Although digital cameras are not nearly as accurate as specialized remote-sensing equipment, they do offer the potential for greater collection opportunities. This study demonstrates the potential of using consumer-grade digital cameras to derive quantitative information from citizen science projects.     

Maximizing lifetime of large-scale wireless sensor networks using multi-objective whale optimization algorithm

Telecommunication Systems - The sink nodes in large-scale wireless sensor networks (LSWSNs) are responsible for receiving and processing the collected data from sensor nodes. Identifying the...     

Energy and Hydraulic Performance-Based Management of Large-Scale Pressurized Irrigation Systems

Improving energy and hydraulic performance of large-scale pressurized irrigation is now perceived as a very pressing need, after large budgets have been allocated into systems modernization. This paper tackles this priority area by developing a management oriented multi-step methodology, that integrates different existing models, to sector the system according to the pressure requirements of the hydrants, and to regulate the pumping station for i) a fixed and a variable pressure head control, and for ii) an enhanced performance. When applied to an on-demand system in the Sinistra Ofanto irrigation scheme of Foggia (Italy), this integrated approach showed potential for energy saving under the optimal scenario of 49 %, and noticeable improvement in the system performance in terms of hydrant pressure heads, as compared to the actual conditions. The monetary assessment demonstrates that the achieved energy saving amounts to 23,636 Euros per irrigation season, 45 % among which are due to sectoring.