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排序方式: 共有398条查询结果,搜索用时 15 毫秒
1.
Advances in the performance of electronic devices have resulted in high input/output counts both at the chip and the package level, which has led to the development of new packaging technologies that can accommodate these high counts. This paper presents and analyzes a novel method for the placement of ball grid array (BGA) bonding pads and routing wires on printed circuit boards to maximize signal density, which ultimately reduces the number of circuit board layers needed for routing. This method has been termed as the "balls shifted as needed" method and all the ball placement/trace routing designs shown in this paper are based on this method. We also present a performance metric defined as the number of balls routed out divided by the area of package footprint on the circuit board, and we compare various placement/routing schemes using this method. 相似文献
2.
A vertebrate host becomes infected with Leishmania major when the sand fly vector injects parasites into skin along with saliva. Previous studies showed that salivary gland lysate of the New World sand fly Lutzomyia longipalpis markedly enhanced L. major infection in CBA mice. However, L. major is an Old World parasite transmitted in nature by the Old World sand fly Phlebotomus papatasi. Here we examine the ability of P. papatasi salivary gland lysate to enhance infection (lesion size and parasite burden) by L. major. In addition, we examine the effects of salivary gland lysate on the immune response to L. major by monitoring the levels of cytokine mRNA from the lymph nodes draining cutaneous lesions. We found that P. papatasi salivary gland lysate dramatically exacerbated lesion development in disease-resistant CBA mice. This exacerbation of disease correlated with inhibition of the production of Thl cytokines and associated factors (IFN-gamma, IL-12, and inducible nitric oxide synthase), but with enhancement of the Th2 cytokine IL-4, whereas no changes in the levels of IL-10 and TGF-beta were noted. Importantly, salivary gland lysate directly up-regulated expression of IL-4 mRNA in mice in the absence of infection with L. major. 相似文献
3.
John J. Guardiola Josiah E. Hardesty Juliane I. Beier Russell A. Prough Craig J. McClain Matthew C. Cave 《International journal of molecular sciences》2021,22(10)
Background: High-level occupational vinyl chloride (VC) exposures have been associated with hepatic hemangiosarcoma, which typically develops following a long latency period. Although VC is genotoxic, a more comprehensive mode of action has not been determined and diagnostic biomarkers have not been established. The purpose of this study is to address these knowledge gaps through plasma metabolomics. Methods: Plasma samples from polyvinyl chloride polymerization workers who developed hemangiosarcoma (cases, n = 15) and VC exposure-matched controls (n = 17) underwent metabolomic analysis. Random forest and bioinformatic analyses were performed. Results: Cases and controls had similar demographics and routine liver biochemistries. Mass spectroscopy identified 606 known metabolites. Random forest analysis had an 82% predictive accuracy for group classification. 60 metabolites were significantly increased and 44 were decreased vs. controls. Taurocholate, bradykinin and fibrin degradation product 2 were up-regulated by greater than 80-fold. The naturally occurring anti-angiogenic phenol, 4-hydroxybenzyl alcohol, was down-regulated 5-fold. Top affected ontologies involved: (i) metabolism of bile acids, taurine, cholesterol, fatty acids and amino acids; (ii) inflammation and oxidative stress; and (iii) nicotinic cholinergic signaling. Conclusions: The plasma metabolome was differentially regulated in polyvinyl chloride workers who developed hepatic hemangiosarcoma. Ontologies potentially involved in hemangiosarcoma pathogenesis and candidate biomarkers were identified. 相似文献
4.
Felix Schmutzler Christopher Zschiesche Juliane Titus David Poppitz Jens Freiding Rainer Rakoczy Andreas Reitzmann Roger Gläser 《化学,工程师,技术》2021,93(6):981-989
The hydroisomerization of two long-chain n-alkane mixtures was investigated over bifunctional Pt/H-ZSM-5 catalysts before and after dealumination of preshaped zeolite/binder pellets. The hydroisomerization over the dealuminated catalysts leads to more isomers and less cracking products. Consequently, higher ratios of multi- to mono-branched isomerization products are formed as expected for large- rather than medium-pore zeolites. This indicates a higher availability of space in the vicinity of the active sites and provides an attractive route to make medium-pore zeolites suitable for upgrading higher boiling hydrocarbon feeds. 相似文献
5.
E. Titus N. Ali G. Cabral J. Gracio P. Ramesh Babu M. J. Jackson 《Journal of Materials Engineering and Performance》2006,15(2):182-186
This article reports key findings on the chemical functionalization of carbon nanotubes (CNT). The functionalization of chemical
vapor-deposited CNT was carried out by treating tubes with polyvinyl alcohol through ultrasonication in water with the aid
of a surfactant. The surfactant is expected to promote the unbundling of aggregated CNT. The characterization of functionalized
samples using thermogravimetric analysis, Fourier transform infrared spectroscopy, and Raman spectroscopy revealed that the
CNT were functionalized by the interaction of carboxylic acid and hydroxyl groups. From the characterization studies, it is
apparent that there is a strong interaction between these functional groups and the covalently bonded carbon in the CNT network.
The functionalization process enabled good CNT dispersion in the solution, and the CNT remained in suspension for many days.
To support the effective functionalization of the tubes, the interaction of functionalized CNT with Ni ions is also demonstrated.
This paper was presented at the fourth International Surface Engineering Congress and Exposition held August 1–3, 2005 in
St. Paul, MN. 相似文献
6.
Ziquan Li Jinquan Wen Yuqing Cai Fengting Lv Xu Zeng Qian Liu Titus Masese Chuanxiang Zhang Xusheng Yang Yanwen Ma Haijiao Zhang Zhen-Dong Huang 《Advanced functional materials》2023,33(22):2300582
Potassium-ion batteries have emerged not only as low-cost alternatives to lithium-ion batteries, but also as high-voltage energy storage systems. However, their development is still encumbered by the scarcity of high-performance electrode materials that can endure successive potassium-ion uptake. Herein, a hydrated Bi-Ti bimetallic ethylene glycol (H-Bi-Ti-EG) compound is reported as a new high-capacity and stable anode material for potassium storage. H-Bi-Ti-EG possesses a long-range disordered layered framework, which helps to facilitate electrolyte ingress into the entire Bi nanoparticles. A suite of spectroscopic analyses reveals the in situ formation Bi nanoparticles within the organic polymer matrix, which can alleviate stresses caused by the huge volume expansion/contraction during deep cycles, thereby maintaining the superior structural integrity of H-Bi-Ti-EG organic anode. As expected, H-Bi-Ti-EG anode exhibits a high capacity and superior long-term cycling stability. Importantly for potassium storage, it can be cycled at current densities of 0.1, 0.5, 1, and 2 Ag−1 for 800, 700, 1000, and even 6000 cycles, retaining charging capacities of 361, 206, 185, and 85.8 mAh g−1, respectively. The scalable synthetic method along with the outstanding electrochemical performance of hydrated Bi-Ti-EG, which is superior to other reported Bi-based anode materials, places it as a promising anode material for high-performance potassium storage. 相似文献
7.
Foehn Philipp Brescianini Dario Kaufmann Elia Cieslewski Titus Gehrig Mathias Muglikar Manasi Scaramuzza Davide 《Autonomous Robots》2022,46(1):307-320
Autonomous Robots - This paper presents a novel system for autonomous, vision-based drone racing combining learned data abstraction, nonlinear filtering, and time-optimal trajectory planning. The... 相似文献
8.
Titus Thankachan K. Soorya Prakash V. Kavimani 《Materials and Manufacturing Processes》2018,33(15):1681-1692
In this research, a copper based surface composite was fabricated through dispersing hybrid composite particles onto its surface through friction stir processing (FSP) technique. Optical micrographs and scanning electron microscopy images indicates finer refinement of grains and particles dispersion into matrix along with its bonding and particle separation. As per the outcomes of microhardness analysis, hardness of the developed surface composite shows increment with increase in dispersion of volume fraction of hybrid particles. Strength of the developed copper surface composite exhibited a positive trend with introduction of hybrid reinforcement particle onto the surface of the composite but yet again ductility reduced. Wear resistance of the composite increased with reinforcement addition and the same was supported through worn out surface morphology. Fluctuations in friction coefficient value reduced with increase in particles, as for the presence in BN particles while the average frictional coefficient value was observed increasing. A reduction in corrosion rate was observed with increase in reinforcement particle dispersion onto copper matrix through FSP. 相似文献
9.
10.
Prediction of noisy chaotic time series using an optimal radialbasis function neural network 总被引:6,自引:0,他引:6
Henry Leung Titus Lo Sichun Wang 《Neural Networks, IEEE Transactions on》2001,12(5):1163-1172
This paper considers the problem of optimum prediction of noisy chaotic time series using a basis function neural network, in particular, the radial basis function (RBF) network. In the noiseless environment, predicting a chaotic time series is equivalent to approximating a nonlinear function. The optimal generalization is achieved when the number of hidden units of a RBF predictor approaches infinity. When noise exists, it is shown that an optimal RBF predictor should use a finite number of hidden units. To determine the structure of an optimal RBF predictor, we propose a new technique called the cross-validated subspace method to estimate the optimum number of hidden units. While the subspace technique is used to identify a suitable number of hidden units by detecting the dimension of the subspace spanned by the signal eigenvectors, the cross validation method is applied to prevent the problem of overfitting. The effectiveness of this new method is evaluated using simulated noisy chaotic time series as well as real-life oceanic radar signals. Results show that the proposed method can find the correct number of hidden units of an RBF network for an optimal prediction. 相似文献