全文获取类型
收费全文 | 873篇 |
免费 | 32篇 |
国内免费 | 2篇 |
专业分类
电工技术 | 61篇 |
综合类 | 3篇 |
化学工业 | 242篇 |
金属工艺 | 14篇 |
机械仪表 | 18篇 |
建筑科学 | 32篇 |
能源动力 | 30篇 |
轻工业 | 95篇 |
水利工程 | 4篇 |
石油天然气 | 1篇 |
无线电 | 58篇 |
一般工业技术 | 134篇 |
冶金工业 | 120篇 |
原子能技术 | 10篇 |
自动化技术 | 85篇 |
出版年
2023年 | 6篇 |
2022年 | 11篇 |
2021年 | 19篇 |
2020年 | 3篇 |
2019年 | 10篇 |
2018年 | 14篇 |
2017年 | 11篇 |
2016年 | 18篇 |
2015年 | 19篇 |
2014年 | 26篇 |
2013年 | 49篇 |
2012年 | 37篇 |
2011年 | 47篇 |
2010年 | 37篇 |
2009年 | 39篇 |
2008年 | 41篇 |
2007年 | 43篇 |
2006年 | 34篇 |
2005年 | 32篇 |
2004年 | 37篇 |
2003年 | 29篇 |
2002年 | 23篇 |
2001年 | 14篇 |
2000年 | 19篇 |
1999年 | 15篇 |
1998年 | 52篇 |
1997年 | 33篇 |
1996年 | 29篇 |
1995年 | 16篇 |
1994年 | 15篇 |
1993年 | 13篇 |
1992年 | 11篇 |
1991年 | 7篇 |
1990年 | 9篇 |
1989年 | 6篇 |
1988年 | 14篇 |
1987年 | 3篇 |
1986年 | 7篇 |
1985年 | 6篇 |
1984年 | 10篇 |
1983年 | 6篇 |
1982年 | 3篇 |
1981年 | 6篇 |
1980年 | 3篇 |
1978年 | 3篇 |
1977年 | 8篇 |
1976年 | 4篇 |
1975年 | 4篇 |
1968年 | 2篇 |
1967年 | 1篇 |
排序方式: 共有907条查询结果,搜索用时 375 毫秒
1.
To enhance chemical stability and suppress of aggregation of magnetite nanoparticles (MNPs), which are used as a support for thermoresponsive copolymer immobilization, silica coating of the MNPs is applied via the electrooxidation method. Although the resulting silica coated-MNPs also formed aggregates, the size distribution of the aggregate shifted to smaller size range. Because of that, the surface area available for copolymer immobilization increased approximately 6.7 times at maximum as compared with that of the uncoated MNPs. It contributed to the increase of the amount of the immobilized copolymer on the silica-coated MNPs, which is approximately four times larger than that on the uncoated MNPs. Fe3O4 dissolution test confirmed enhancement of chemical stability of MNPs. The thermoresponsive copolymer immobilized on the silica-coated MNPs shows the ability to recycle Cu(II) ion from Cu(II) containing solution by changing temperature with significantly shorter time than those in other thermoresponsive adsorbents in gel form. 相似文献
2.
A Synthetic Transcriptional Activator of Genes Associated with the Retina in Human Dermal Fibroblasts
下载免费PDF全文
![点击此处可从《Chembiochem : a European journal of chemical biology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
3.
Akiko Suzuki Mina Minamide Chihiro Iwaya Kenichi Ogata Junichi Iwata 《International journal of molecular sciences》2020,21(23)
Carbohydrates, fats, and proteins are the underlying energy sources for animals and are catabolized through specific biochemical cascades involving numerous enzymes. The catabolites and metabolites in these metabolic pathways are crucial for many cellular functions; therefore, an imbalance and/or dysregulation of these pathways causes cellular dysfunction, resulting in various metabolic diseases. Bone, a highly mineralized organ that serves as a skeleton of the body, undergoes continuous active turnover, which is required for the maintenance of healthy bony components through the deposition and resorption of bone matrix and minerals. This highly coordinated event is regulated throughout life by bone cells such as osteoblasts, osteoclasts, and osteocytes, and requires synchronized activities from different metabolic pathways. Here, we aim to provide a comprehensive review of the cellular metabolism involved in bone development and homeostasis, as revealed by mouse genetic studies. 相似文献
4.
U Semba Y Shibuya S Tanase N Nishino Y Makinose T Kambara H Okabe T Yamamoto 《Canadian Metallurgical Quarterly》1993,1180(3):267-276
Human and guinea pig Hageman factors have been subjected to the action of pseudomonal elastase and serratial E15 proteinase. The pseudomonal elastase cleaved 22-24% of the human molecule at Arg353-Val354, and the remainder at Gly357-Leu358 resulting in the generation of about 20% of potential activity as activated Hageman factor, compared with trypsin activation, while it hydrolyzed Arg340-Ile341 bond in guinea pig molecule and generated about 75% of activity as activated Hageman factor. The serratial proteinase did not hydrolyze the essential cleavage site (Arg353-Val354) of the human zymogen but Gly356-Gly357 (30%) and Gly357-Leu358 (70%) bonds. Both products showed no activity. The guinea pig zymogen, in contrast, was cleaved mostly at Arg340-Ile341 (70%) and less abundantly at Gly344-Leu345 (30%), generating about 85% of the whole potential activity as activated Hageman factor. From the high correspondence between the proportions of activation and of hydrolysis at the essential cleavage site in activation, it was concluded that hydrolysis of the bonds different from the essential bond did not cause activation, even when the spatial separation was only 3 or 4 residues. Considering the amino acid differences between human and guinea pig Hageman factors, -Met351-Thr-Arg-Val-Val-Gly-Gly-Leu-Val-Ala360- and -Leu338-Ser-Arg-Ile-Val-Gly-Gly-Leu-Val-Ala347-, respectively, it was realized that even the minor amino acid substitutions caused the cleavage site shift which resulted in significant differences in activation efficiency of the proteinase zymogens. 相似文献
5.
6.
Makikazu Takehana Tomomichi Nishino Katsuyasu Sugawara Takuo Sugawara 《Korean Journal of Chemical Engineering》1996,13(5):538-543
Cobalt-, praseodymium-added zinc oxide varistor was prepared through a wet chemical method followed by sintering with or without
calcination. Changes in grain size, compact density, additives distribution, and voltagecurrent/ capacitance-voltage relations
were investigated for the characterization of the samples sintered at temperatures from 1473 to 1573 K without calcination
or with calcination at 773 K for 2 h. The electrical properties were compared with nhose of samples prepared by two types
of ball mill methods. The wet chemical method provided almost the same additives-distribution profile and less impurities
in comparison with the ball grinding method carried out for 10–100 h. The donor concentration and the potential-barrier height
for the samples were evaluated by Double Schottky Barrier Model. Addition of small amount of both cobalt and praseodymium
in preparation by the wet chemical method was effective for a better nonlinearity relation between voltage and current, which
has potential for a smaller sized varistor. 相似文献
7.
Plastic deformation in a multifunctional Ti-Nb-Ta-Zr-O alloy 总被引:7,自引:0,他引:7
S. Kuramoto T. Furuta J. H. Hwang K. Nishino T. Saito 《Metallurgical and Materials Transactions A》2006,37(3):657-662
Mechanisms for plastic deformation in the newly developed Ti-24 at. pct (Ta + Nb + V)-(Zr,Hf)-O alloys (Gum Metal) were investigated
in relation to their unique properties. Transmission electron microscopy revealed that the microstructure after deformation
was characterized by highly distorted crystal images, which are accompanied by numerous “giant faults.” Such plastic behavior
implies that a large amount of elastic stain energy was stored discretely and hierarchically during cold working. Calculated
elastic constants of the Ti-X (Nb,Ta,Mo,V) binary systems predicted that Young’s modulus in 〈001〉 and shear moduli along some
directions including slip systems in a bcc crystal were extraordinary small. The low modulus not only well explains the highly
distorted microstructure observed in the cold-worked specimens, but also signifies that ideal shear strength of the developed
alloys is a very small value, which is close to the practical strength required for plastic deformation in the alloy. This
implies that the giant faults observed in the deformed specimen were formed without the aid of dislocation glide. 相似文献
8.
High performance liquid chromatographic separation of a series of mono-, di- and trihydroxylated 5β-cholanic acids which differ
only in position and configuration of hydroxyl groups at positions C-3, C-7 and/or C-12, is reported. The C-24 free acids
were derivatized to four different classes of UV-sensitive esters, i.e.,p-bromophenacyl (BP),m-methoxyphenacyl (MP), 4-nitrophthalimidemethyl (NPM) and 9-anthrylmethyl (AM) esters, and chromatographed on two, variants
of C18 reversed-phase columns (Nova-Pak C18 and Zorbax ODS) with methanol-water systems as mobile phase. Separation efficiency and elution order of some isomeric pairs
were influenced by both the structure of the C-24 ester groups and the nature of the columns used. Excellent chromatographic
properties were found for those derivatives, particularly for the NPM esters. 相似文献
9.
Y Nakamura Y Horii T Nishino H Shiiki Y Sakaguchi T Kagoshima K Dohi Z Makita H Vlassara R Bucala 《Canadian Metallurgical Quarterly》1993,143(6):1649-1656
Advanced glycosylation end products (AGEs) accumulate on long-lived extracellular matrix proteins and have been implicated in the micro- and macrovascular complications of diabetes mellitus. Within the arterial wall, AGE-modified proteins increase vascular permeability, inactivate nitric oxide activity, and induce the release of growth-promoting cytokines. Recently developed anti-AGE antibodies were used in an immunohistochemical analysis of coronary arteries obtained from type II diabetic and nondiabetic patients. High levels of AGE reactivity were observed within the atherosclerotic plaque present in vessels from selected patients with diabetes. Considered together with the pathological effects of AGEs on vascular wall homeostasis, these data support the role of advanced glycosylation in the rapidly progressive atherosclerosis associated with diabetes mellitus. 相似文献
10.
Teruya Tanaka Junichi. H. Kaneko Yoshimi Kasugai Masaki Katagiri Hiroshi Takeuchi Takeo Nishitani Toshiyuki Iida 《Diamond and Related Materials》2005,14(11-12):2031
Radiation tolerance of a type IIa synthetic diamond detector was examined from irradiation of mono-energetic 14 MeV neutrons. Measurements of I–V (current–voltage) characteristics and energy spectrum for 5.486 MeV alpha particles were performed after neutron irradiation. In the I–V characteristics measurement, enhancement of rectification was observed after neutron irradiation of up to 2.0 × 1012 n/cm2. Concurrently with the enhancement of rectification, significant decrease in signal amplitude was observed in energy spectrum measurement for alpha particles. It is considered that these changes were due to increase in the concentration of defects acting as shallow energy levels in the forbidden band. For neutron irradiation of higher than 1.6 × 1013 n/cm2, weakening of the rectification characteristics and recovery of the signal amplitude were observed. These changes imply that deep energy levels, which were also considered to be introduced by defects, were dominant and weakened the effects of the shallow energy levels. Increase in the concentration of the deep trapping levels resulted in gradual decrease of the signal amplitude and degradation in the energy resolution. The peak for the alpha particles was obtained up to 5.5 × 1013 n/cm2. 相似文献