Effects of cytogenin on spontaneous arthritis in MRL/1 mice and on pristane-induced arthritis (PIA) in DBA/1J mice

Cytogenin, 8-hydroxy-3-hydroxymethyl-6-methoxyisocoumarin, has low cytotoxicity on murine and human tumour cells in vitro. It augments or suppresses phagocytosis of macrophages and lymphocyte proliferation. It has been reported that cytogenin has a potent inhibitory effect clinically on adjuvant arthritis in Lewis rats and on type II collagen-induced arthritis in DBA/1J mice. Our experimental findings provide evidence that cytogenin has beneficial effects on spontaneous polyarthritis in MRL/1 mice and pristane-induced arthritis in DBA/1J mice. The results suggest that the mode of the anti-arthritic action of cytogenin is different from those of NSAIDs; although the precise mode of action remains unclear, cytogenin may become an excellent therapeutic agent for rheumatoid arthritis.     

Pixel-selected ray tracing

An acceleration method based on an idea that T. Whitted (Commun. ACM, vol.23, no.6 pp.343-349, June 1980) presented on ray tracing is discussed. He proposed making antialiased images by hierarchical adaptive oversampling. The present authors use hierarchical adaptive undersampling to reduce the number of pixels whose intensity must be calculated by ray tracing. To implement pixel-selected ray tracing (PSRT), homogeneous regions in images must first be found. Generally, adaptive undersampling can result in some image-quality defects, because small objects and parts of thin or wedge-shaped objects may disappear when they are located between the initially sampled pixels. PSRT has an improved algorithm that uses pixels with the correct object information from among the sampled pixels to find pixels with erroneous color and correct them. Moreover, PRST uses ray-object intersection trees for precise classification of the homogeneity of regions and for fast intensity calculation in homogeneous regions. Experimental results are presented. They show that PSRT is two to nine times faster than standard ray tracing     

A coarse-to-fine IP-driven registration for pose estimation from single ultrasound image

A fast registration making use of implicit polynomial (IP) models is helpful for the real-time pose estimation from single clinical free-hand Ultrasound (US) image, because it is superior in the areas such as robustness against image noise, fast registration without enquiring correspondences, and fast IP coefficient transformation. However it might lead to the lack of accuracy or failure registration.In this paper, we present a novel registration method based on a coarse-to-fine IP representation. The approach starts from a high-speed and reliable registration with a coarse (of low degree) IP model and stops when the desired accuracy is achieved by a fine (of high degree) IP model. Over the previous IP-to-point based methods our contributions are: (i) keeping the efficiency without requiring pair-wised correspondences, (ii) enhancing the robustness, and (iii) improving the accuracy. The experimental result demonstrates the good performance of our registration method and its capabilities of overcoming the limitations of unconstrained freehand ultrasound data, resulting in fast, robust and accurate registration.     

A framework of general instruments for multimedia art creation

In this paper, we propose a framework to develop general instruments for multimedia art creation. Recently, many attempts at creating multimedia art have been made with the aid of computer technology. However, a system for a certain artwork is usually dedicated to the artwork and cannot be applied to other artwork. After overviewing the prerequisites for a general multimedia instrument, we propose a framework for such a system. This framework is based on giving attention to common attributes among several multiple media. Moreover, we illustrate prototype instruments constructed in accordance with this framework. Finally, we show the results of an evaluative performance with the prototype instruments.     

Synthesis of polyamide-hydroxyapatite nanocomposites

Simultaneous one-pot syntheses of PA66 and HAp were carried out by extracting H₂O and CO₂ from PA66 monomers and HAp raw materials, respectively, resulting in the formation of a polyamide (PA) 66-hydroxyapatite (HAp) nanocomposite. During the process, a spherical nano-sized HAp particle was precipitated following dissolution of micro-sized CaHPO₄・2H₂O. The PA66 monomers were subsequently adsorbed onto the generated HAp product. Some of the adsorbed PA66 monomers formed a bound polymer on HAp, and an increase in the adhesiveness of the PA66-HAp interface was observed as the polymerization progressed. During this process, the synthesis of a nanocomposite from a micro-sized raw material and creation of an autonomous strong interface between the matrix and filler was achieved. In addition, the shape of the resultant HAp was controllable and could be modified to needle shape by the addition of F⁻ and Mg²⁺ ions to the raw material. HAp could also be changed to plate shape via octa-calcium phosphate (OCP). Notably, during the synthesis, the filler shape of the nanocomposite could be controlled to 0D (particle), 1D (needle), and 2D (plate).     

Determining surface orientations of transparent objects based on polarization degrees in visible and infrared wavelengths

Techniques for modeling an object through observation are very important in object recognition and virtual reality. A wide variety of techniques have been developed for modeling objects with opaque surfaces, whereas less attention has been paid to objects with transparent surfaces. A transparent surface has only surface reflection; it has little body reflection. We present a new method for obtaining surface orientations of transparent surfaces through analysis of the degree of polarization in surface reflection and emission in visible and far-infrared wavelengths, respectively. This parameter, the polarization degree of reflected light at the visible wavelengths, is used for determining the surface orientation at a surface point. The polarization degree at visible wavelengths provides two possible solutions, and the proposed method uses the polarization degree at far-infrared wavelengths to resolve this ambiguity.     

Conference assistant system for supporting knowledge sharing in academic communities

This paper describes our ongoing attempts to build a communityware system by presenting a project of providing digital assistants to support participants in an academic conference. We provided participants at the conference with a personal assistant system with mobile and ubiquitous computing technologies and facilitated communication among the participants. We also made online services available via the Web to encourage the participants to continue their relationships even after the conference. In this paper, we show the system we provided for the project and report the results.     

Illumination normalization with time-dependent intrinsic images for video surveillance

Variation in illumination conditions caused by weather, time of day, etc., makes the task difficult when building video surveillance systems of real world scenes. Especially, cast shadows produce troublesome effects, typically for object tracking from a fixed viewpoint, since it yields appearance variations of objects depending on whether they are inside or outside the shadow. In this paper, we handle such appearance variations by removing shadows in the image sequence. This can be considered as a preprocessing stage which leads to robust video surveillance. To achieve this, we propose a framework based on the idea of intrinsic images. Unlike previous methods of deriving intrinsic images, we derive time-varying reflectance images and corresponding illumination images from a sequence of images instead of assuming a single reflectance image. Using obtained illumination images, we normalize the input image sequence in terms of incident lighting distribution to eliminate shadowing effects. We also propose an illumination normalization scheme which can potentially run in real time, utilizing the illumination eigenspace, which captures the illumination variation due to weather, time of day, etc., and a shadow interpolation method based on shadow hulls. This paper describes the theory of the framework with simulation results and shows its effectiveness with object tracking results on real scene data sets.     

The separation of reflected and transparent layers from real-world image sequence

This paper presents an optimal method for the separation of reflected and transparent layers from real-world scene images. Whereas past research has been applied to indoor environments and static cameras, our technique can be used for outdoor scenes and motion cameras. The method is based on spatio-temporal analysis, especially using epipolar plane images (EPI). The edge and color information of EPI has been used to segment the areas on EPIs efficiently and separate the reflected and transparent layers. This method can be used for refining building textures by removing reflections from captured images for the purpose of city modeling.