全文获取类型
收费全文 | 513篇 |
免费 | 7篇 |
国内免费 | 1篇 |
专业分类
电工技术 | 42篇 |
化学工业 | 113篇 |
金属工艺 | 14篇 |
机械仪表 | 7篇 |
建筑科学 | 5篇 |
能源动力 | 22篇 |
轻工业 | 20篇 |
水利工程 | 1篇 |
无线电 | 38篇 |
一般工业技术 | 79篇 |
冶金工业 | 72篇 |
原子能技术 | 11篇 |
自动化技术 | 97篇 |
出版年
2023年 | 4篇 |
2022年 | 8篇 |
2021年 | 10篇 |
2020年 | 7篇 |
2019年 | 5篇 |
2018年 | 7篇 |
2017年 | 10篇 |
2016年 | 9篇 |
2015年 | 8篇 |
2014年 | 9篇 |
2013年 | 28篇 |
2012年 | 26篇 |
2011年 | 32篇 |
2010年 | 18篇 |
2009年 | 24篇 |
2008年 | 34篇 |
2007年 | 12篇 |
2006年 | 24篇 |
2005年 | 23篇 |
2004年 | 18篇 |
2003年 | 15篇 |
2002年 | 9篇 |
2001年 | 11篇 |
2000年 | 8篇 |
1999年 | 10篇 |
1998年 | 29篇 |
1997年 | 20篇 |
1996年 | 17篇 |
1995年 | 10篇 |
1994年 | 9篇 |
1993年 | 10篇 |
1992年 | 4篇 |
1991年 | 3篇 |
1990年 | 3篇 |
1989年 | 6篇 |
1988年 | 6篇 |
1987年 | 4篇 |
1986年 | 4篇 |
1985年 | 2篇 |
1984年 | 2篇 |
1983年 | 3篇 |
1981年 | 2篇 |
1980年 | 2篇 |
1977年 | 1篇 |
1976年 | 5篇 |
1975年 | 3篇 |
1972年 | 2篇 |
1968年 | 1篇 |
1959年 | 1篇 |
1957年 | 1篇 |
排序方式: 共有521条查询结果,搜索用时 31 毫秒
1.
Although the precise pathoetiology of Beh?et's disease (BD) remains obscure, patients with BD have a high incidence of chronic infectious foci, indicating an enhanced susceptibility to chronic tonsillitis, and dental caries. Sometimes, clinical symptoms appear after treatment of these foci in BD patients. It is believed that BD might be related to an allergic reaction to a bacterial infection in view of the many clinical symptoms, especially the presence of aphthous and genital ulcerations. An attempt to obtain cutaneous responses to bacterial antigens has been carried out using various vaccines developed from bacteria isolated from the ulcerative lesions and oral cavities of BD patients. BD patients often show intense hypersensitivity to various strains of streptococci, not only by their cutaneous reactions but also by in vitro testing. In this report, we describe our previous studies on the correlation between streptococcal antigens and the pathogenesis of BD and also discuss the recent reports of other authors. The intense hypersensitivity to streptococcal antigens acquired after streptococcal infection is thought to play an important role in the appearance of symptoms in BD patients since the production of pro-inflammatory cytokines by peripheral blood mononuclear cells (PBMC) was enhanced when stimulated with streptococcal antigen in a culture system. Minocycline, an antibiotic to which certain strains of streptococci are sensitive, reduced the frequency of clinical symptoms in BD patients as well as the production of pro-inflammatory cytokines by BD-PBMC stimulated with streptococcal antigen. 相似文献
2.
T Oyama T Osaki T Mitsudomi R Ogawa R Nakanishi K Sugio K Yasumoto 《Canadian Metallurgical Quarterly》1998,1(5):823-826
We examined p53 protein expression, p53 gene mutation, proliferating cell nuclear antigen (PCNA), and argyrophilic nuclear organizer regions (AgNOR), in 30 patients with surgically-treated thymic tumors (26 thymoma and 4 thymic carcinoma cases). p53 expression ratio with DO-1 was divided as p53 negative (0% positivity), low expressor (<10% positivity), high expressor (>10% positivity). The incidence of p53 low and high expressor in thymoma were 19% (5/26) and 8% (2/26), respectively. p53 immunopositivity in thymoma was significantly correlated with PCNA labeling index (LI). p53 expression ratio in invasive thymoma (33%) tended to be higher than that in non-invasive thymoma (18%). p53 expression was detected in one of the thymic carcinoma. There were no p53 gene mutations in 15 invasive thymoma, although one of four (25%) thymic carcinomas showed two point mutations. p53 gene alterations seem to be associated with malignant activity of tumor cells, and therefore detection of p53 gene mutations is useful as a diagnostic factor. 相似文献
3.
T Shirasaka K Nakano T Takechi H Satake J Uchida A Fujioka H Saito H Okabe K Oyama S Takeda N Unemi M Fukushima 《Canadian Metallurgical Quarterly》1996,56(11):2602-2606
The purpose of this study was to establish a nude rat orthotopic (organ-specific) human colorectal cancer model as an in vivo secondary screen for general evaluation of new anticancer agents against colorectal cancer and to evaluate practically the antitumor activity of 1 M tegafur-0.4 M 5-chloro-2,4-dihydroxypyridine-1 M potassium oxonate (S-1), a new p.o. fluoropyrimidine, in comparison to 1 M tegafur-4 M uracil [(UFT) effective on colorectal tumor in clinical]. After implantation of KM12C, a human colorectal cancer cell line, into the subserosal layer of the colon as a single-cell suspension, extensive local tumor growth and invasion to both the mucosal and the serosal sides were observed in all rats. Metastatic foci were also formed in both lymph nodes and lungs following local tumor growth in all of them. Using this method, an equitoxic dose of S-1 (15 mg/kg/day) and UFT (30 mg/kg/day) was administered p.o. for 14 consecutive days from 7 days after tumor cell implantation. S-1 showed a higher tumor growth inhibition than UFT did [S-1, 57% (significantly different from the tumor weight of the untreated group at P < 0.05) and UFT, 18% (P > 0.05)]. When both drugs were administered to nude rats bearing KM12C injected into the cecal wall for 28 consecutive days at equitoxic doses, the mean survival in the S-1 group was 16 days longer than that in the untreated group (P < 0.01) but that in the UFT group was only 8 days longer (P > 0.05). After the administration of an equitoxic dose of both drugs, S-1 gave the higher levels than UFT in various pharmacokinetic parameters as follows: area under the curve 0-24 h of 5-fluorouracil in plasma (3.5-fold), area under the curve 0-24 h of 5-fluorouracil incorporated into RNA in the tumor (1.3-fold), and thymidylate synthase inhibition rate (percentage) in the tumor (about 20%). Collectively, these findings suggested that this orthotopic human colorectal tumor model in nude rats is useful to evaluate the clinical therapeutic efficacy of drugs or therapies for colorectal cancer, and that S-1 had a higher therapeutic effect on human colorectal tumor than UFT did. 相似文献
4.
A screening test was undertaken to isolate a microorganism that produced 5-oxoprolinase (without ATP-hydrolyzing). The 5-oxoprolinase (without ATP-hydrolyzing) activity (decyclization activity toward L-pyroglutamate) was found in a cell-free extract of Alcaligenes faecalis N-38A, newly isolated from a soil sample. The enzyme was purified as a homogeneous preparation. The molecular weight of the enzyme was estimated to be 47,000. The decyclization activity was specific for L-pyroglutamate, and independent of ATP and metal ions. The reaction was a reversible one, i.e., cyclization reaction of L-glutamate to yield pyroglutamate was identified. 相似文献
5.
Hiromi Nakano Keigo Suzuki Kazunori Kizima 《Journal of the American Ceramic Society》2006,89(4):1461-1464
The thermal behavior of nanoparticles BaTiO3 , prepared by a radio-frequency plasma chemical vapor deposition (RF-plasma CVD) method, was characterized by various analysis methods. The BaCO3 phase was included in the powder as byproducts, which is also observed in hydrothermal BaTiO3 powder. The BaCO3 phase decomposed and disappeared by annealing at 873 K for 30 min. H2 O, N2 , CO2 and H2 , were detected by a thermal desorption spectra measurement from BaTiO3 powder. The annealed powder became well-crystallized particles without grain growth, although as-prepared powder included polycrystalline particles. We successfully observed in-situ grain growth for BaTiO3 nanoparticles by thermal transmission electron microscope. At the initial step of normal grain growth, very fine particles with 40–60 nm diameters started to merge into the larger grains around 1083 K. The migration rate was measured by video images and a grain boundary diffusion coefficient Dgb was calculated. 相似文献
6.
Keigo Hirakata Wendell E. Rhine Michael J. Cima 《Journal of the American Ceramic Society》1996,79(4):1002-1008
Carbon residue after binder burnout was characterized for several nonstoichiometric lead titanate powders. Thermal decomposition of the poly(methyl methacrylate) (PMMA) binder was performed in nitrogen at 600°C. A drastic decrease in carbon retention was obtained in the case of the titanium-rich samples. The amount of carbon retention varies from 0.2 mg/m2 to 1.2 mg/m2 by changing the Pb/Ti molar ratio from 0.92 to 1.08. The surface reaction between PMMA and lead titanate particles was studied by diffuse reflectance Fourier transform infrared spectroscopy (DRIFTS). Surface hydroxyls reacted with ester groups in the PMMA or the methylmethacrylate monomer produced upon pyrolysis. The DRIFTS results showed that titaniumrich samples are less reactive and produce less surfacebound organic groups. Interestingly, titanium-rich samples contained more surface hydroxyls. Isoelectric point measurements, however, show that titanium-rich samples are more acidic. Thus, the reactivity of the surface hydroxyls is determined primarily by their acid-base characteristics rather than their concentration. Lead titanate powder was exposed to MMA vapor in a tube furnace at the indicated temperatures using nitrogen carrier gas as a model experiment. DRIFTS difference spectroscopy and Raman spectroscopy were performed on these samples after the exposure. MMA reacts with lead titanate powder in manner similar to PMMA. Analysis for sp 2 and sp 3 absorbance of Raman spectra of these exposed powders at 400°–600°C showed pyrolysis behavior of surface-reacted species. The relative amount of sp 2 bonded carbon decreases with increasing exposure temperature. 相似文献
7.
8.
9.
A new class of materials, MI-MII-O-N (where MI, MII = V, Mo, W, and Nb), has been synthesized by nitriding bimetallic oxide precursors with ammonia gas via a temperature programmed reaction. The oxide precursors are prepared by conventional solid state reaction between two appropriate monometallic oxides. The synthesis of the oxynitrides involves passing NH3 gas over the oxide precursors at a flow rate of 6.80×102 mols–1 (1000 cm3 min–1), and raising the temperature at a rate of 8.3×10–2 Ks–1 (5K min–1) to a final temperature which is held constant for a short period of time. The oxynitrides thus obtained are pyrophoric and need to be passivated before exposing them to air. All these new bimetallic oxynitrides have a face centered cubic (f.c.c.) metal arrangement and high values of surface area. Their surface activity is assessed from their ability to chemisorb CO. 相似文献
10.
Fusaomi Nagata Takanori Mizobuchi Shintaro Tani Tetsuo Hase Zenku Haga Keigo Watanabe Maki K. Habib 《Artificial Life and Robotics》2010,15(1):106-110
In this article, a new desktop orthogonal-type robot, which has the capacity of stick-slip motion control based on cutter
location data, is presented for lapping small metallic molds with a curved surface. The robot consists of three single-axis
devices with a high position resolution of 1 μm. A thin wooden stick tool with a ball-end shape is attached to the tip of
the z-axis. In order to improve the lapping performance, a novel stick-slip motion control method is developed in the control system.
The small stick-slip motion is orthogonally generated in the direction of the tool’s movement. The effectiveness of stick-slip
motion control is examined through an actual lapping test of an LED lens cavity. 相似文献