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C Nishiyama M Fukada Y Usui N Iwamoto T Yuuki Y Okumura H Okudaira 《Canadian Metallurgical Quarterly》1995,32(14-15):1021-1029
Der f 2 is a major mite allergen composed of 129 amino acid residues. To determine the major epitopes on Der f 2 recognized by human IgE antibodies, artificial mutations were introduced to Der f 2 protein. The IgE-binding activity of Der f 2 was significantly decreased by deletion of 10 amino acids at the N-terminus or nine amino acids at the C-terminus. Site-directed mutagenesis with a single amino acid replacement by Ala or Leu in both N- and C-terminal regions as well as a central portion was performed to generate 42 single-site mutations. Amino acid replacement around a disulfide bond of Cys8-Cys119 caused a marked decrease in IgE-binding activity. Furthermore, a distinct decrease in IgE-binding was also caused by Ala-substitution close to a disulfide bond of Cys73-Cys78 and by mutations of a few charged residues. From these results, it was concluded that the two disulfide-forming regions of Der f 2 and several charged residues are important for forming major epitope structures recognized by human IgE antibodies. 相似文献
4.
Masahiro Baba Goh Itoh Haruhiko Okumura 《Journal of the Society for Information Display》2007,15(3):205-211
Abstract— In this paper, a software‐processed edge‐ and level‐adaptive overdrive (SELAO) method, which is a novel overdrive technique that utilizes not only a temporal change of gray levels but also a spatial edge intensity of motion pictures, is proposed. The SELAO method is a software video‐processing technology to improve motion‐picture quality rendered on LCDs more than is possible with a conventional SLAO method without edge‐adaptive overdrive, and it works in real time on commonly used personal computers (PCs). 相似文献
5.
A unique substrate MCPM (Mitsubishi Copper Polyimide Metal-base) technology has been developed by applying our basic copper/polyimide
technology.1 This new substrate technology MCPM is suited for a high-density, multi-layer, multi-chip, high-power module/package, such
as used for a computer. The new MCPM was processed using a copper metal base (110 × 110 mm), full copper system (all layers)
with 50-μm fine lines. As for pad metallizations for the IC assembly, we evaluated both Ni/Au for chip and wire ICs and solder
for TAB ICs. The total number of assembled ICs is 25. To improve the thermal dispersion, copper thermal vias are simultaneously
formed by electro-plating. This thermal via is located between the IC chip and copper metal base, and promotes heat dispersion.
We employed one large thermal via (4.5 mm?) and four small vias (1.0 mm?) for each IC pad. The effect of thermal vias and/or base metal is simulated by a computer analysis and compared with an alumina
base substrate. The results show that the thermal vias are effective at lowering the temperature difference between the IC
and base substrate, and also lowering the temperature rise of the IC chip. We also evaluated the substrate’s reliability by
adhesion test, pressure cooker test, etc. 相似文献
6.
Kiichi Oda Hirohide Yata Tetsuo Yoshio Kazuo O-Oka Kohei Oda 《Journal of Materials Science》1986,21(2):637-642
Ta100-x
B
x
alloy films were prepared by r.f.-sputtering in the chemical composition range 45 x 77. Ta100-x
B
x
(45 x 58) films consist of the amorphous phase, while the TaB2 crystal phase was observed in Ta100-x
B
x
(66 x 77) films. A remarkable preferred orientation with the (001) plane of TaB2 parallel to the film surface was observed in Ta34B66. The d.c. electrical conductivity of Ta100-x
B
x
(45 x 77) films decreases with increasing boron content in the range 6.7 × 103 to 1.3 × 103–1 cm–1. The micro-Vickers hardness of Ta100-x
B
x
(45 x 77) films was in the range 2200 to 2600 kg mm–2. 相似文献
7.
Co-N films in the wide compositional range can be prepared by reactive sputtering. Co-N sputtered films consist of one or two phases, such as CoN, Co2N, Co3N, Co4N and -Co. Co4N phase with a cubic unit cell is observed, and its lattice constant isa = 0.3586 nm. The preferred orientation is observed on the Co-N films, CoN (200) plane, Co4N (1 1 1) plane and -Co (002) plane parallel to the film surface, respectively. Saturation magnetization s of Co-N sputtered film decreases from 160 to 1.7 e.m.u. g–1 with increasing content of N from 0 to 21.7 at%, and coercive forceI
H
c is the range of 43 to 5000e at room temperature. 相似文献
8.
Poly(p-phenylene terephthalamide) (PPTA) was blended with poly(vinyl chloride) (PVC) by solution-blending method. PPTA was metalated for dissolving in dimethyl sulfoxide. Dimethyl sulfoxide was used as a common solvent. In PPTA/PVC composite, PPTA accelerated the thermal degradation of PVC. PPTA molecules are aggregated as microfibrillar form in PVC matrix. Such microfibrils are dispersed homogeneously in PVC matrix, according to polarizing microscopic observation. The average diameter of the microfibrils becomes smaller in the composite with lower content of PPTA. In the surface region of PPTA microfibrils the intermolecular hydrogen bonds between C? Cl of PVC and N? H of PPTA are formed. Young's modulus and the yield stress at room temperature were higher in the composites than those in PVC. The modulus of the composites was higher, especially at the high temperatures above their glass transition temperatures, than that in PVC. The temperature dependence of modulus can be calculated by using the mechanical model equivalent to the quasi-3-dimensional microfibrillar model which will be approximately applied to the composite structure. It becomes apparent that the modulus of the PPTA microfibrils evaluated by using the mechanical model is higher in the higher molecular weight PPTA. 相似文献
9.
Surface‐modified polypropylene (PP) films with thermally and photochemically sensitive copolymers consisting of N‐(2‐hydroxypropyl)methacrylamide (HPMA) and 4‐(4‐methoxyphenylazo)phenyl methacrylate (MPAP), poly(HPMA‐co‐MPAP)‐g‐PP (abbreviated g‐PP) film, were prepared by graft copolymerization with an Ar‐plasma postpolymerization technique. The surfaces of the g‐PP films were characterized by means of X‐ray photoelectron spectroscopy; the percentage grafting of poly(HPMA‐co‐MPAP) with a number‐average molecular weight of 3.28 × 104 was 7.12%, and the molar ratio of HPMA–MPAH in the copolymer was 0.75:0.25. The stimuli‐sensitive adsorption of albumin and polystyrene microspheres on the g‐PP film was also measured. © 2003 Wiley Periodicals, Inc. J Appl Polym Sci 90: 143–148, 2003 相似文献
10.
Yasuhiro Jimbo Yuki Tamatsukuri Minato Ito Kohei Yokoyama Yoshiharu Hirakata Shunpei Yamazaki 《Journal of the Society for Information Display》2015,23(7):313-318
To improve the reliability and mechanical durability of a flexible organic light‐emitting diode display, the entire flexible display is coated with an aluminum oxide film by atomic layer deposition (ALD). Because the step coverage of ALD is excellent, the AlOx film was deposited not only on the front and back surfaces but also on the side surfaces of the display. A high‐temperature and high‐humidity preservation test, repetitive bending tests, and a pencil hardness test were conducted on the flexible display with ALD‐AlOx coating. The display survived 500 h of a 65°C, 95% preservation test, endured a 100,000‐time repetitive bending test with a curvature radius of 4 mm, and was found to have a pencil hardness of 4H. 相似文献