Role of Zinc (Zn) in Human Reproduction: A Journey from Initial Spermatogenesis to Childbirth

Zinc (Zn), the second-most necessary trace element, is abundant in the human body. The human body lacks the capacity to store Zn; hence, the dietary intake of Zn is essential for various functions and metabolism. The uptake of Zn during its transport through the body is important for proper development of the three major accessory sex glands: the testis, epididymis, and prostate. It plays key roles in the initial stages of germ cell development and spermatogenesis, sperm cell development and maturation, ejaculation, liquefaction, the binding of spermatozoa and prostasomes, capacitation, and fertilization. The prostate releases more Zn into the seminal plasma during ejaculation, and it plays a significant role in sperm release and motility. During the maternal, labor, perinatal, and neonatal periods, the part of Zn is vital. The average dietary intake of Zn is in the range of 8–12 mg/day in developing countries during the maternal period. Globally, the dietary intake of Zn varies for pregnant and lactating mothers, but the average Zn intake is in the range of 9.6–11.2 mg/day. The absence of Zn and the consequences of this have been discussed using critical evidence. The events and functions of Zn related to successful fertilization have been summarized in detail. Briefly, our current review emphasizes the role of Zn at each stage of human reproduction, from the spermatogenesis process to childbirth. The role of Zn and its supplementation in in vitro fertilization (IVF) opens opportunities for future studies on reproductive biology.     

Application of outranking methods to economic and financial justificaton of CIM systems

Traditional economic evaluation methods concentrate on maximizing or minimizing a single objective such as net present value and pay back period. In the last decade, there has been an increased awareness of the need to consider multiple attributes in the evaluation of advanced manufacturing systems. Various methods have recently been developed for the evaluation of CIM systems. This paper discusses multiattribute methods for justification of CIM systems and outranking methods including ELECTRE, ORESTE, and PROMETHEE.     

Influence of BaO on Pd/Al2O3-based catalysts in C2H4 and CO oxidation as well as in NO reduction

In this study, Pd/Al₂O₃ and Pd/BaO/Al₂O₃ metallic monoliths were used to investigate the effect of BaO in C₂H₄ and CO oxidation as well as in NO reduction. A FT-IR gas analyser was used to study the activity of the catalysts. Several activity experiments carried out with dissimilar feedstreams revealed that BaO enhances CO and C₂H₄ oxidation as well as NO reduction reactions in rich conditions. This effect is due to BaO, which causes a decrease in the ethene poisoning of palladium. In lean conditions BaO is present in the form of Ba(OH)₂ which reacts with oxidised NO releasing water. Therefore, NO was stored during the lean reaction.     

Influence of OSC material on the behaviour of metallic Pd catalysts in C2H4 and CO oxidation as well as in NO reduction

Topics in Catalysis - The interaction of CO, C2H4, O2, and NO reaction gas compounds over the metallic Pd/Al2O3 and Pd/OSC/Al2O3 monoliths was investigated in order to understand the behaviour of...     

Regulation of proteins mediating neurodegeneration in experimental autoimmune encephalomyelitis and multiple sclerosis

Multiple sclerosis is characterized by inflammatory demyelination and axonal loss as pathophysiological correlates of relapsing activity and progressive development of clinical disability. The molecular processes involved in this pathogenesis are still unclear as they are quite complex and heterogeneous. In this article we present protein expression analysis of brain and spinal cord tissues from different models of murine experimental autoimmune encephalomyelitis (EAE), the most commonly used animal model for multiple sclerosis. We observed a number of EAE-specific protein expression and PTM differences. Proteome analysis was extended to multiple sclerosis specimens in order to validate the EAE findings. Our findings suggest the regulation of a number of proteins that shed light on the molecular mechanisms of the disease processes taking place in EAE and multiple sclerosis. We found consistent modulation of proteins including serum amyloid P component, sirtuin 2, dihydropyrimidinase-related protein family proteins, stathmin 1, creatine kinase B and chloride intracellular channel protein 1. Functional classification of the proteins by database and the literature mining reveals their association with neuronal development and myelinogenesis, suggesting possible disease processes that mediate neurodegeneration.     

A new method using feature extraction for identifying paddy rice species for quality seed selection

The purpose of this work was to explore a new feature extraction method for classifying paddy seeds using a feature extraction algorithm to achieve the area ratio, horizontal–slant and front–rear angles and find whether the proposed features have high discriminating power. Another objective was to find the smallest feature set that can ensure highly accurate recognition of seeds. A total of a 100 image features were extracted, and features having significant discriminating power were identified based on the analysis of variance (ANOVA). From the 100 features, 14 features were found to have high discriminating power and from these features, six were selected as the proposed features. Experimental results show that the proposed features and removal of redundant features enhanced the discriminating power of the feature set, and that the proposed features have an excellent discriminating property for seeds. The presented features resulted in the highest classification accuracy (98.8%) when compared to other methods.     

Gendering the digital body: women and computers

As we live in a culture where “everything can be commodified, measured and calculated and can be put in the competitive market for sale, detached from its roots and purpose,” there is need to redefine our humanness in terms of the changing nature of science, technology, and their deeper impact on human life. More than anything else, it is Information Technology that now has tremendous influence on all spheres of our life, and in a sense, IT has become the destiny of our life. And this is where the real trauma lies. On the one hand, our being in the cyberspace opens up new and exciting horizons before us; on the other hand, we ourselves are changed and transformed in the process. The virtual world transforms human users to a problem-solver technocrat. The speed at which Information Technology is changing the way that youth around the world are socializing, playing, and researching, it is the common practice now for a 15-year old to go home and update their MySpace page, followed by playing online games, or looking up the new trendy YouTube video. These forms of technology are often the topic of adolescent conversations as YouTube, blogs, e-magazines, Face book, MySpace, iPhones, and iPods dominate the commercial and social networking market. Some researchers refer to this phenomenon as ubiquitous technology drawing attention to the fact that ubiquitous technology acknowledges the speedy adoption of day-to-day use of technology as a global phenomenon. In this background, this article aims at revisiting the question, “What is to be human in the era of Ubiquitous Technology?” From a feminist perspective, one can still redefine the boundaries between femininity and masculinity in the context of IT and its impact on our lifestyle and thought style. While examining the ways in which our definitions of “woman” and “man” are shifting in this new communication environment, Elizabeth Lane Lawley observes that we cannot fix a single center from which the experiences of women with computer and communication systems can be viewed and that such fixity would only serve to deepen inequities rather than exposing and removing them. She finally submits, “It is possible to use new theoretical perspectives on the shifting boundaries of gender definitions to rethink a previously deterministic view of the effect of new technologies on society, and particularly the effect of those technologies on women. While the gradual absence of the subject from the field of Artificial Intelligence leads to the invisibility of feminine care along with social and relational nature of man, some feminists dismiss the biological sex distinction on such issues and encourage females to ‘imitate man’ and to become more aggressive, assertive and dominating” (Lawley 1993). What are the possible impacts of this new technology on the so-called feminine traits of our human nature? How far our definitions of “woman” and “man” are shifting in this new communication environment? This is what this article seeks to explore.     

A design approach for systems based on magnetic pulse compression

A design approach giving the optimum number of stages in a magnetic pulse compression circuit and gain per stage is given. The limitation on the maximum gain per stage is discussed. The total system volume minimization is done by considering the energy storage capacitor volume and magnetic core volume at each stage. At the end of this paper, the design of a magnetic pulse compression based linear induction accelerator of 200 kV, 5 kA, and 100 ns with a repetition rate of 100 Hz is discussed with its experimental results.     

Green microalga Chlorella vulgaris as a potential feedstock for biodiesel

BACKGROUND: A major bottleneck in microalgal biodiesel production is lipid content, which is often low in microalgal species. The present study examines Chlorella vulgaris as a potential feedstock for biodiesel by identifying and evaluating the relationships between the critical variables that enhance the lipid yield, and characterizes the biodiesel produced for various properties. RESULTS: Factors affecting lipid accumulation in a green microalga, Chlorella vulgaris were examined. Multifactor optimization raised the lipid pool to 55% dry cell weight against 9% control. When C. vulgaris cells pre‐grown in glucose (0.7%)‐supplemented medium were transferred to the optimized condition at the second stage, the lipid yield was boosted to 1974 mg L^?1, a value almost 20‐fold higher than for the control. The transesterified C. vulgaris oil showed the presence of ～82% saturated fatty acids, with palmitate and stearate as major components, thus highlighting the oxidative stability of C. vulgaris biodiesel. The fuel properties (density, viscosity, acid value, iodine value, calorific value, cetane index, ash and water contents) are comparable with the international (ASTM and EN) and Indian (IS) biodiesel standards. CONCLUSION: C. vulgaris biomass with 55% lipid content and adequate fuel properties is potentially a renewable feedstock for biodiesel. Copyright © 2011 Society of Chemical Industry